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La carta dei sentieri della Comunità Montana Valtellina di Tirano. Il progetto pilota della val Grosina
No full textPeripheral nerve findings in hereditary coproporphyria. Light and ultrastructural studies in two sural nerve biopsies.
No full textIn spite of several cases reported in the literature, the exact pathogenetic mechanism of neuropathic changes in porphyric neuropathy remains uncertain. Various authors have ascribed the neuropathologic findings to either a dying-back axonal degeneration or segmental demyelination. In recent years, the hypothesis of an axonal and myelinic disorder has received support by the demonstration of a combined and simultaneous involvement of both these structures. Such different opinions are also a consequence of the reduced number of detailed bioptic observations in the different forms of acute porphyria not only during acute phases but also between attacks. In this paper we report the results of light- and electron-microscopic examination of two sural nerve biopsies from subjects with hereditary coproporphyria. The first was performed 6 months after an acute attack, the second specimen was obtained from a patient without acute attacks, who had clinical and electrophysiologic signs of a chronic progressive neuropathy. In both cases a dying-back axonal degeneration is considered the primary change. The pathogenetic mechanism of peripheral nerve lesions in porphyric neuropathy will be discussed finally
Anatomo-clinical correlations in normotensive hydrocephalus. Reports on three cases
No full textThe brains of 3 adult subjects suffering from normotensive hydrocephalus have been examined pathologically. The diagnosis of normotensive hydrocephalus was based on clinical symptoms, pneumoencephalography and isotope cisternography, in 1 case integrated with the results of the constant-infusion manometric test. Part of the neuropathological findings were common to the 3 patients: leptomeningeal non-obstructive fibrosis, ventricular ependymal disruption, subependymal glial reaction, periventricular demyelination and spongiosis. Other neuropathological abnormalities were peculiar to each patient: leptomeningeal signs of previous subarachnoid haemorrhage; arteriosclerosis and multiple brain cystic infarcts; Alzheimer's plaques in the gray matter. The possible pathogenetic significance of the neuropathological findings summarized above in relation to the development of normotensive hydrocephalus is discussed
[Brain malformations in a case of camptomelic syndrome]
No full textThe camptomelic syndrome is characterised by neonate dwarfism of micromelic type with multiple anomalies of the skeletal system and peculair facies (bridge of the nose flattened, jutting occiput, full forehead, low set ears and micrognathia) often associated with split palate. The incurving of the anterior convexity of the tibia is pathognomonic. Respiratory distress is frequently encountered both at birth and later. Death is almost early, occurring neonatally or in the first months of life. The etiology has been widely discussed with the genetic hypothesis the most widely held. Unlike other forms of neonate dwarfism associated malformations of the trachea, bronchi, kidneys, heart and brain tissues are often found. Cerebral malformations are fairly common, with agenesis of the olfactory nerves mentioned in several cases. The case described here has been observed from clinical and anatomopathological viewpoints. (Rush - Oxford
I DB topografici in Regione Lombardia: la sperimentazione del repertorio regionale ed il passaggio al repertorio nazionale
No full text[Shy-Drager's syndrome during a course of vascular arteriosclerotic disease and diabetes mellitus]
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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