1,720,986 research outputs found
Confronto di alcuni caratteri biometrici tra le aree di allevamento del bovino Podolico. I. Rilievi infra vitam
Il sottosistema agricolo-zootecnico nelle comunità montane del Fortore, sub-appenino Dauno meridionale, Lambro e Mingardo.
Attività del Laboratorio di Meccanica Del Volo dell’Università di Bologna, nell’ambito dei Sistemi Avionici
La presente memoria riporta una descrizione delle attività di ricerca e dei sottosistemi sviluppati presso il Laboratorio di Meccanica del Volo dell’ Università di Bologna. La ricerca, nel primo anno di attività del Laboratorio, ha riguardato principalmente problematiche di modellazione, simulazione e controllo del volo atmosferico, con particolare riferimento alle applicazioni nell’ambito dei velivoli non abitati (UAV), e nella memoria si riporta una sintesi delle attività di ricerca riguardanti la progettazione, la prototipazione, e la sperimentazione di sistemi di bordo per velivoli abitati e non abitati in corso di svolgimento presso il Laboratorio di Meccanica del Volo dell’ Università di Bologna. In particolare vengono descritti un sistema per un velivolo non abitato ed un sistema di ausilio al pilotaggio rivolto sia a velivoli abitati che pilotati in remoto da una stazione di terra. Sono infine presentati i principali risultati sperimentali ottenuti con i suddetti sistemi
Sostituzione valvolare aortica in pazienti con stenosi aortica e comprommissione della funzione ventricolare sinistra: follow-up a medio e lungo termine
Longitudinal study of endothelial function in children with familial hypercholesterolemia.
Endothelial function (EF) is impaired in diseases associate with vascular complications, such as diabetes and familialhypercholesterolemia (FH). The impairment of EF assessed as flow mediated dilation (FMD) of brachial artery can predict futurecardiovascular disease. To assess the alteration of EF, we longitudinally evaluate FMD in prepubertal patients with geneticallyconfirmed FH. Twelve children (7 M, 5 F; 8.19±2.90 yr.) with FH and 20 control subjects entered the study. Subjects withdiabetes, obesity or other metabolic disorders were excluded. In all FH patients lipid values and FMD were determined at thebeginning of the study and after 32.8±9.55 mo. of diet low in saturated fat and cholesterol. FMD function was assessed bymeasurement of endothelium-dependent vasodilation of the brachial artery using an ultrasound system. FMD was expressed aspercentage change of diameter following reactive hyperemia from baseline. The lower FMD values obtained in our control patientwas 7% so we considered it as cut-off. The baseline evaluation showed that FMD in FH children was not significantly different thancontrol peers (20.9±23.3 vs 12.5±7.28%; p=0.143). According to sex, M were significantly older than F and had a longer followup (38.1±7.52 vs 25.5±7.09 mo.; p = 0.015). At the end of the study, despite T-CH, LDL, HDL, and TG levels were unmodified,FMD values significantly decreased (20.9±23.3 vs 2.75±9.07%; p=0.034) resulting significantly lower than in normal subjects(p=0.002). The impairment was shown in 75% vs. 25% of children found at the start. No correlation was demonstrated betweenFMD and lipid levels, age and duration of the follow-up. Our data show that after few years patients with FH have a decrease ofFMD values not apparently related to lipid control or to duration of diet. This difference, more evident in males, suggests that furtherstudies are needed to better understand which factors are involved in functional changes of endothelial dysfunction
Comparing real-time PCR and bacteriological cultures for Streptococcus agalactiae and Staphylococcus aureus in bulk-tank milk samples
For more than 30 yr, a control plan for Streptococcus agalactiae and Staphylococcus aureus has been carried out in more than 1,500 dairy herds of the province of Brescia (northern Italy). From 2010 to 2011, the apparent prevalence of Strep. agalactiae has been relatively stable around 10%, but the apparent prevalence of Staph. aureus has been greater than 40% with an increasing trend. The aim of this paper was to estimate and compare the diagnostic accuracy of 3 assays for the detection of Strep. agalactiae and Staph. aureus in bulk-tank milk samples (BTMS) in field conditions. The assays were a qualitative and a quantitative bacteriological culture (BC) for each pathogen and a homemade multiplex real-time PCR (rt-PCR). Because a gold standard was not available, the sensitivities (Se) and specificities (Sp) were evaluated using a Bayesian latent class approach. In 2012 we collected one BTMS from 165 dairy herds that were found positive for Strep. agalactiae in the previous 2-yr campaigns of eradication plan. In most cases, BTMS collected in these herds were positive for Staph. aureus as well, confirming the wide spread of this pathogen. At the same time we also collected composite milk samples from all the 8,624 lactating cows to evaluate the within-herd prevalence of Strep. agalactiae. Streptococcus agalactiae samples were cultured using a selective medium Tallium Kristalviolette Tossin, whereas for Staph. aureus, we used Baird Parker modified medium with added Rabbit Plasma Fibrinogen ISO-Formulation. In parallel, BTMS were tested using the rt-PCR. Regarding Strep. agalactiae, the posterior median of Se and Sp of the 2 BC was similar [qualitative BC: Se = 98%, posterior credible interval (95%PCI): 94–100%, and Sp = 99%, 95%PCI: 96–100%; quantitative BC: Se = 99%, 95%PCI: 96–100%, and Sp = 99%, 95%PCI: 95–100%] and higher than those of the rt-PCR (at 40 cycle threshold, Se = 92%, 95%PCI: 85–97%; Sp = 94%, 95%PCI: 88–98%). Also in case of Staph. aureus, the posterior medians of BC were generally higher than those of rt-PCR. In fact, although the Se of BC was slightly lower (rt-PCR at 40 cycle threshold, median Se = 99%, 95%PCI: 97–100%, and qualitative BC, median Se = 94%, 95%PCI: 87–99%), the Sp was much higher (rt-PCR at 40 cycle threshold, median Sp = 67%, 95%PCI: 38–97%; qualitative BC, median Sp = 95%; 95%PCI: 76–100%). Our study confirms that BC and rt-PCR are reliable diagnostic tools to detect Strep. agalactiae and Staph. aureus, and rt-PCR results should be confirmed by BC carried out on BTMS and possibly on composite milk samples
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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