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J. J. Crosetti: Pajaro Valley Agriculture, 1927 to 1977
.J. Crosetti was the founder of the J.J. Crosetti lettuce growing company in the Pajaro Valley, California, which is still in operation today under his son, J.J. Crosetti, Jr. Crosetti began his career in California agriculture as a contract buyer for the T.J. Horgan Company during the late 1920s and early 1930s, and then worked as a buyer for A. Levy and Sentner Distributors in San Francisco. In 1936 Crosetti founded his own company, growing and shipping lettuce, tomatoes, broccoli, apples and other crops primarily in the Pajaro Valley, but also in Arizona and the Imperial Valley of California. Crosetti describes labor operations and packing and shipping methods, including the details of the development of vacuum cooling. He discusses the Bracero Program and ethnic changes in the agricultural labor force from the 1930s to the 1970s. He describes the development of labor organizing in Central California and his own involvement in union contract negotiations. Crosetti was also active in the Grower Shipper Vegetable Association of Central California for many years, and served on the State Board of Agriculture as an appointee of Governor Edmund G. Brown from 1962-1969. He concludes the volume with a discussion of economic and technological changes in California agriculture and the increasing trend away from family farmers towards conglomerates
Molecular markers as conservation tools in a marine stock enhancement program aiming at the restoration of the endangered dusky grouper, Epinephelus marginatus
Partial Laryngeal Surgery in 2023
Open partial horizontal laryngectomies (OPHLs) have emerged as a pivotal strategy in the conservative treatment of intermediate to advanced stages of laryngeal cancer (LC). This review evaluates the evolution of surgical approaches, focusing on maintaining laryngeal function while ensuring oncological safety. Initially, total laryngectomy dominated the therapeutic landscape, prioritizing tumor control over organ preservation. However, with advancements in understanding LC’s natural history, patient selection and surgical techniques, there has been a paradigm shift towards organ-preserving surgical options like OPHLs. Modern OPHL techniques, backed by enhanced endoscopic and radiological assessments, allow for precise tumor assessment and surgical planning, increasing the likelihood of preserving crucial laryngeal functions such as speech and swallowing. High-definition videolaryngoscopy and magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) have improved the accuracy of pre-operative work-up, thereby refining patient eligibility for partial laryngectomy. The integration of modular surgical approaches and the adoption of new classification by the European Laryngological Society (ELS) further support the versatility of OPHLs in addressing diverse tumor localizations and extents. The review underscores the competitive oncological outcomes of OPHLs compared to non-surgical organ-preservation protocols, highlighting the significant rates of laryngectomy-free survival and the maintenance of laryngeal function. Despite these advances, the treatment of advanced LC remains challenging due to the complex nature of tumor biology and the critical need for precise clinical and pathological assessments. The necessity for a multidisciplinary approach in treatment planning is emphasized to balance oncological control with functional preservation effectively. In conclusion, OPHLs represent a robust option in the current armamentarium for treatment of LC, providing a substantial foundation for enhancing both patient survival and quality of life. The strategic integration of surgical innovations and comprehensive pre-operative assessments is crucial in optimizing treatment outcomes and advancing the field of laryngeal preservation
Le cisti mucoidi del vestibolo nasale: esperienza su 3 casi e revisione della letteratura.
Unravelling the risk factors that underlie laryngeal surgery in elderly
Older patients are not considered good candidates to undergo more challenging therapeutic treatments, e.g. highly invasive surgery and complex chemotherapy. However, their exclusion from standard therapeutic options is not justifiable. Herein, we reviewed 212 patients aged ≥ 70, affected with laryngeal squamous cell carcinoma, and treated with transoral laser microsurgery or open neck (partial / total) laryngectomy with radical intent. The main aim was to compare patient outcomes to identify predictive factors that can be used by surgeons to choose the most appropriate treatment option. In our cohort, patients affected with more advanced tumour and hence treated by invasive open neck surgeries (above all TL) are more prone to develop complications and undergo fatal outcome than those with early disease treated by laser microsurgery, independently of age at surgery. In conclusion, elderly patients affected by laryngeal cancer can be treated similarly to younger patients, keeping in mind that more invasive surgeries are associated with a higher risk of developing complications. The advantages of mini-invasive surgery make it a possible first choice treatment in very old and frail patients suffering from laryngeal cancer, especially considering the recent success in treatment of some advanced stage tumours. Furthermore, comorbidities, by themselves, should not be used as exclusion criteria for subjecting an elderly patient to a different treatment that is from standard therapy
Long-term functional results after open partial horizontal laryngectomy type IIa and type IIIa : a comparison study
BACKGROUND:
The purpose of this study was to compare long-term swallowing, voice results, and quality of life (QOL) after open partial horizontal laryngectomy (OPHL) type IIa and type IIIa.
METHODS:
Twenty-three patients after OPHL type IIa and 18 patients after OPHL type IIIa were involved. Swallowing skills and neoglottis' motility and vibrations were videoendoscopically assessed. Aerodynamic measures, spectrogram analysis, aspiration pneumonia, body weight variations, and voice perceptual assessment were performed. Generic voice-related and swallowing-related QOL were assessed. Data were statistically compared using Mann-Whitney U test or Fisher exact tests, as appropriate.
RESULTS:
Significant differences were found only for the residue with solids and for the intelligibility (I) parameter of the overall quality impression and intelligibility, additive and unnecessary noise, speech fluency, and presence of voiced segments scale with patients of the OPHL type IIIa group showing worse performances than the OPHL type IIa group.
CONCLUSION:
Patients who underwent OPHL type IIa and type IIIa show comparable long-term functional outcomes. OPHL type IIIa represents a valid surgical alternative to OPHL type II
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