1,716 research outputs found

    Partial Laryngeal Surgery in 2023

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    Open partial horizontal laryngectomies (OPHLs) have emerged as a pivotal strategy in the conservative treatment of intermediate to advanced stages of laryngeal cancer (LC). This review evaluates the evolution of surgical approaches, focusing on maintaining laryngeal function while ensuring oncological safety. Initially, total laryngectomy dominated the therapeutic landscape, prioritizing tumor control over organ preservation. However, with advancements in understanding LC’s natural history, patient selection and surgical techniques, there has been a paradigm shift towards organ-preserving surgical options like OPHLs. Modern OPHL techniques, backed by enhanced endoscopic and radiological assessments, allow for precise tumor assessment and surgical planning, increasing the likelihood of preserving crucial laryngeal functions such as speech and swallowing. High-definition videolaryngoscopy and magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) have improved the accuracy of pre-operative work-up, thereby refining patient eligibility for partial laryngectomy. The integration of modular surgical approaches and the adoption of new classification by the European Laryngological Society (ELS) further support the versatility of OPHLs in addressing diverse tumor localizations and extents. The review underscores the competitive oncological outcomes of OPHLs compared to non-surgical organ-preservation protocols, highlighting the significant rates of laryngectomy-free survival and the maintenance of laryngeal function. Despite these advances, the treatment of advanced LC remains challenging due to the complex nature of tumor biology and the critical need for precise clinical and pathological assessments. The necessity for a multidisciplinary approach in treatment planning is emphasized to balance oncological control with functional preservation effectively. In conclusion, OPHLs represent a robust option in the current armamentarium for treatment of LC, providing a substantial foundation for enhancing both patient survival and quality of life. The strategic integration of surgical innovations and comprehensive pre-operative assessments is crucial in optimizing treatment outcomes and advancing the field of laryngeal preservation

    Unravelling the risk factors that underlie laryngeal surgery in elderly

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    Older patients are not considered good candidates to undergo more challenging therapeutic treatments, e.g. highly invasive surgery and complex chemotherapy. However, their exclusion from standard therapeutic options is not justifiable. Herein, we reviewed 212 patients aged ≥ 70, affected with laryngeal squamous cell carcinoma, and treated with transoral laser microsurgery or open neck (partial / total) laryngectomy with radical intent. The main aim was to compare patient outcomes to identify predictive factors that can be used by surgeons to choose the most appropriate treatment option. In our cohort, patients affected with more advanced tumour and hence treated by invasive open neck surgeries (above all TL) are more prone to develop complications and undergo fatal outcome than those with early disease treated by laser microsurgery, independently of age at surgery. In conclusion, elderly patients affected by laryngeal cancer can be treated similarly to younger patients, keeping in mind that more invasive surgeries are associated with a higher risk of developing complications. The advantages of mini-invasive surgery make it a possible first choice treatment in very old and frail patients suffering from laryngeal cancer, especially considering the recent success in treatment of some advanced stage tumours. Furthermore, comorbidities, by themselves, should not be used as exclusion criteria for subjecting an elderly patient to a different treatment that is from standard therapy

    Long-term functional results after open partial horizontal laryngectomy type IIa and type IIIa : a comparison study

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    BACKGROUND: The purpose of this study was to compare long-term swallowing, voice results, and quality of life (QOL) after open partial horizontal laryngectomy (OPHL) type IIa and type IIIa. METHODS: Twenty-three patients after OPHL type IIa and 18 patients after OPHL type IIIa were involved. Swallowing skills and neoglottis' motility and vibrations were videoendoscopically assessed. Aerodynamic measures, spectrogram analysis, aspiration pneumonia, body weight variations, and voice perceptual assessment were performed. Generic voice-related and swallowing-related QOL were assessed. Data were statistically compared using Mann-Whitney U test or Fisher exact tests, as appropriate. RESULTS: Significant differences were found only for the residue with solids and for the intelligibility (I) parameter of the overall quality impression and intelligibility, additive and unnecessary noise, speech fluency, and presence of voiced segments scale with patients of the OPHL type IIIa group showing worse performances than the OPHL type IIa group. CONCLUSION: Patients who underwent OPHL type IIa and type IIIa show comparable long-term functional outcomes. OPHL type IIIa represents a valid surgical alternative to OPHL type II
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