1,251 research outputs found

    Livello sonoro allo interno dell'abitacolo dei mezzi di trasporto in presenza di rivestimento fonoassorbente

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    La memoria riferisce sui risultati della attivita di ricerca svolta nell' ambito del Progetto Finalizzato Trasporti (P.F.T.) del C.N.R., tendente a studiare il campo acustico dell' abitacolo dei mezzi di trasporto mediante tecniche numeriche agli elementi finiti e modelli in scala

    New enteric-coated high-lipase pancreatic extract in the treatment of pancreatic steatorrhea

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    We studied a new enteric-coated pancreatic extract with very high lipase content in 12 patients with steatorrhea due to chronic pancreatitis. Fecal fat was measured under standard dietary conditions (100 g lipid/day) with no enzyme supplementation and during treatment with 75,000, 150,000, or 225,000 IU of lipase per day. The median fecal fat output (g/day) was significantly (p < 0.005) lower after each increase in dosage: basal, 20.5 (range, 10.3-92.2); 3 cps/day at meals, 13.3 (6.4-38.2); 6 cps/day, 9.9 (4.8-31.4); 9 cps/day, 7.3 (2.6-17.3). For the five patients with a basal fecal fat output of < 15 g/day, steatorrhea was totally corrected by 3 cps a day. Of the seven patients with more severe steatorrhea, the fecal fat output of only two was not normalized with the highest dose of 9 cps/day: for one it was reduced to 13.3 g/day from a basal of 92.2 g/day and for the other to 17.3 g/day from 25.4 g/day. This pilot study demonstrates that the tested pancreatic extract very effectively corrects pancreatic steatorrhea in a simple low-dose regimen. Good compliance can be expected

    Purification and assay of secretory lithostathine in human pancreatic juice by fast protein liquid chromatography

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    Impaired secretion of lithostathine, a pancreatic glycoprotein capable of inhibiting the growth of CaCO3 crystals, has been reported in chronic calcifying pancreatitis. Controversial results were obtained, however, using immunoassays with different antibodies. The aim of this study was to purify and to measure juice lithostathine by a non-immunological method. Fast protein liquid chromatography (FPLC) on a cation exchange column eluted by a sodium chloride gradient, was used. The conditions appropriate to separate secretory (S) from hydrolysed (H) isoforms of immunopurified lithostathine were also used for juice analysis. Pancreatic juice was collected by endoscopic cannulation of the major pancreatic duct, after secretin stimulation, from eight patients with chronic pancreatitis (CP) and from eight controls. In all samples, S-isoforms of lithostathine (ranging from 16 to 19 Mr at SDS-PAGE) were the only constituent of two of the 15 peaks in which FPLC resolved the pancreatic proteins. The nature of these two peaks was confirmed by their coelution with immunopurified S-lithostathine and by immunoblot analysis with polyclonal anti-lithostathine antibodies. The ratio between the area of S-lithostathine peaks and the total area of proteic eluates, was always lower in CP patients (5.3 micrograms/mg of protein, median value; 0.2-15.4, range) than in controls (35.2 micrograms/mg; 16.6-55.9). It is concluded that lithostathine can be purified and measured in pancreatic juice by FPLC. Our results with a nonimmunological assay confirm a reduced secretion of lithostathine in patients with CP

    Letteratura e mezzi di trasporto

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    Il progetto si propone di organizzare un convegno e un percorso didattico multimediale finalizzato a un master professionalizzante per gli studenti che attivi risorse scientifiche internazionali e istituzioni culturali nazionali sul tema letteratura e mezzi di trasporto

    Mezzi didattici

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    Dai mezzi più tradizionali ieri e/o ancora oggi utilizzati nella prassi didattica a quelli della tecnologia moderna, audiovisiva e informatic

    Mezzi adeguati alle esigenze di vita e criteri di calcolo delle prestazioni previdenziali nella prospettiva costituzionale

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    Il saggio indaga la portata della formula “mezzi adeguati alle esigenze di vita”. A tal fine, il saggio ricostruisce le linee essenziali del dibattito dottrinale. In particolare, rileva l’inidoneità dell’art. 36 Cost a fornire un affidabile criterio di determinazione delle prestazioni adeguate e l’esito del dibattito, di semplice convalida e razionalizzazione ex post delle scelte legislative. Ripartendo dall’art. 38 Cost. e dai lavori preparatori prospetta una diversa configurazione dei mezzi adeguati, per quanto di difficile attuazione

    L'impiego dei mezzi di contrasto in Radiologia. Aspetti medico-legali.

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    Gli autori discutono i profili di responsabilità in radiodiagnostica, con particolare riguardo ai problemi della responsabilità professionale connessa all'uso dei mezzi di contrast
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