1,402 research outputs found
Beware of surrogate outcome measures
No full textSurrogate outcome measures may speed up clinical research if they can be measured earlier in a study than the primary outcome of interest. We review the justification for their use and conclude that reliance on them may be harmful. Results obtained with surrogates should therefore be regarded as preliminary. Large, definitive trials with clinically relevant outcomes should always be performed before new interventions are accepted
Academic authorship: who, why and in what order?
No full textWe are frequently asked by our colleagues and students for advice on authorship for scientific articles. This short paper outlines some of the issues that we have experienced and the advice we usually provide. This editorial follows on from our work on submitting a paper1 and also on writing an academic paper for publication.2 We should like to start by noting that, in our view, there exist two separate, but related issues: (a) authorship and (b) order of authors. The issue of authorship centres on the notion of who can be an author, who should be an author and who definitely should not be an author, and this is partly discipline specific. The second issue, the order of authors, is usually dictated by the academic tradition from which the work comes. One can immediately envisage disagreements within a multi-disciplinary team of researchers where members of the team may have different approaches to authorship order
Interview With P.C. Hodgell
No full textP.C. Hodgell, author of God Stalk and Dark of the Moon, was one of the many authors who attended Mythcon XIX in Berkeley last summer. She was good enough to meet with the Mythic Circle writers\u27 roundtable and share some of her experiences with us. The following is transcribed from a low-quality tape; when it was possible to recognize a speaker’s voice I have identified them - others are noted as ct. Hope you enjoy it
Nonequilibrium and classical dissipation scalings in DNS of homogeneous isotropic decaying turbulence
No full textWe present data from direct numerical simulations of homogeneous isotropic decaying turbulence showing both the non-equilibrium and the classical dissipation scalings reported in wind-tunnel experiments of both regular and fractal grid-generated turbulence, i.e. Cε ∼ (Re0/Reλ)n with n of order unity and Cε ∼ constant, respectively (Re0 and Reλ are global and local Reynolds numbers). These two dissipation behaviours lead to different power-law decay exponents in both regimes also in accord with the experiments. Finally, we show that in both regimes the maximum non-linear energy cascade flux, Π, reasonably satisfies the classical expectation that Π ∼ K3/2/l
The Strengthening the Reporting of Observational Studies in Epidemiology [STROBE] statement: guidelines for reporting observational studies
No full textMuch biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalisability. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) initiative developed recommendations on what should be included in an accurate and complete report of an observational study. We defined the scope of the recommendations to cover three main study designs: cohort, case-control, and cross-sectional studies. We convened a 2-day workshop in September, 2004, with methodologists, researchers, and journal editors to draft a che-cklist of items. This list was subsequently revised during several meetings of the coordinating group and in e-mail discussions with the larger group of STROBE contributors, taking into account empirical evidence and methodological considerations. The workshop and the subsequent iterative process of consultation and revision resulted in a checklist of 22 items (the STROBE statement) that relate to the title, abstract, introduction, methods, results, and discussion sections of articles. 18 items are common to all three study designs and four are specific for cohort, case-control, or cross-sectional studies. A detailed explanation and elaboration document is published separately and is freely available on the websites of PLoS Medicine, Annals of Internal Medicine, and Epidemiology. We hope that the STROBE statement will contribute to improving the quality of reporting of observational studies
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration
No full textSystematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users. Since the development of the QUOROM (QUality Of Reporting Of Meta-analysis) Statement-a reporting guideline published in 1999-there have been several conceptual, methodological, and practical advances regarding the conduct and reporting of systematic reviews and meta-analyses. Also, reviews of published systematic reviews have found that key information about these studies is often poorly reported. Realizing these issues, an international group that included experienced authors and methodologists developed PRISMA ( Preferred Reporting Items for Systematic reviews and Meta-Analyses) as an evolution of the original QUOROM guideline for systematic reviews and meta-analyses of evaluations of health care interventions. The PRISMA Statement consists of a 27-item checklist and a four-phase flow diagram. The checklist includes items deemed essential for transparent reporting of a systematic review. In this Explanation and Elaboration document, we explain the meaning and rationale for each checklist item. For each item, we include an example of good reporting and, where possible, references to relevant empirical studies and methodological literature. The PRISMA Statement, this document, and the associated Web site (http://www.prisma-statement.org/) should be helpful resources to improve reporting of systematic reviews and metaanalyses
Reinforcing glass with glass: Application of transport reinforcement in structural glass beams
No full textDue to the increasing demand of transparency in buildings, it is no longer unusual to apply transparent elements into the bearing structure. Glass is a strong but very brittle material, which means safety is rather problematic should it break. Safety is an issue that has to be improved before glass can be considered suitable for structural elements. Earlier studies have shown that reinforcing glass beams will provide reasonable residual load-bearing capacity, which could provide this safety. Glass fibre is suitable as reinforcement material when the transparency is regarded as important. In February 2009 at the Faculty of Architecture at Delft University of Technology, P.C. Louter designed and tested a laminated glass beam with embedded glass fibre rods. The bonding interlayer consisted of SentryGlas foil, developed by DuPont and often applied for lamination in hurricane-resistant windows. The results were promising and the concept showed high potential for further research. The study of this thesis project is focussed on improving the concept of embedding reinforcement in laminated glass beams.Design and ConstructionCivil Engineering and Geoscience
Foreign Direct Investment. The key determinants of foreign direct investment in Poland. Case company: ArgusPack P.C.
No full textThe aim of this thesis was to provide a better understanding of the determinants of foreign direct invest-ment (referred to hereafter as “FDI”). The company ArgusPack P.C. is a flexible packaging manufacturer located in Greece which decided to engage using FDI in Poland. Thus, the factors that favors FDI into the selected region had to be determined.
This thesis was a qualitative research, an empirical non-numerical data research. For primary data a series of interviews was conducted by the author and for secondary data peer-reviewed articles and literatures that fully-describe the determinants of FDI were utilized. There are numerous theories that define the FDI, such as Vernon’s product life cycle (Vernon, 1966), Buckley and Casson’s internalization theory (P. Buckley, 1976) and Dunning’s eclectic paradigm (Dunning J. , 2001). In this project, the Dunning’s eclectic paradigm theory was selected and applied, aiming to provide a better understanding of the factors that motivates a company or an organization to become involved using FDI. Through a research study the primary data were collected and through excessive academic research the secondary data were collected as well. In conclu-sion, an analysis of the primary data in combination with the secondary data was done mainly focusing on the participants’ point of view and the way it aligns with the theoretical aspect given by this thesis. In the end a conclusion and recommendation were formed based on all data mentioned and the personal belief of the author.
Finally, since the key determinants have been identified and examined. Foreign direct investment seems to be an adequate business strategy for ArgusPack P.C. in Polan
The Quest for Citations: Drivers of Article Impact
No full textWhy do some articles become building blocks for future scholars, while many others remain unnoticed? We aim to answer this question by contrasting, synthesizing and simultaneously testing three scientometric perspectives – universalism, social constructivism and presentation – on the influence of article and author characteristics on article citations. To do so, we study all articles published in a sample of five major journals in marketing from 1990 to 2002 that are central to the discipline. We count the number of citations each of these articles has received and regress this count on an extensive set of characteristics of the article (i.e. article quality, article domain, title length, the use of attention grabbers and expositional clarity), and the author (i.e. author visibility and author personal promotion). We find that the number of citations an article in the marketing discipline receives, depends upon “what one says†(quality and domain), on “who says it†(author visibility and personal promotion) and not so much on “how one says it†(title length, the use of attention grabbers, and expositional clarity). Our insights contribute to the marketing literature and are relevant to scientific stakeholders, such as the management of scientific journals and individual academic scholars, as they strive to maximize citations. They are also relevant to marketing practitioners. They inform practitioners on characteristics of the academic journals in marketing and their relevance to decisions they face. On the other hand, they also raise challenges towards making our journals accessible and relevant to marketing practitioners: (1) authors visible to academics are not necessarily visible to practitioners; (2) the readability of an article may hurt academic credibility and impact, while it may be instrumental in influencing practitioners; (3) it remains questionable whether articles that academics assess to be of high quality are also managerially relevant.Impact;Citation Analysis;Referencing;Scientometrics;Cite
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