1,720,960 research outputs found
Video laparoscopic cholecystectomy in a case of biliary lithiasis associated with gallbladder tuberculosis. Considerations and review of the literature [Videolaparocolecistectomia in un caso di litiasi biliare associata a tubercolosi della colecisti. Considerazioni e revisione della letteratura]
No full textThe authors report a case of gallbladder stones with tuberculosis of gallbladder, operated for laparoscopic cholecystectomy. From the review of the literature two basic data stand out: the exceptionality of gallbladder's tuberculosis with stones at the same time and the opportunity to make the diagnosis of tuberculosis of the gallbladder only by the histological examination after cholecystectomy
Panatrophy of Gowers associated with primary antiphospholipid syndrome: Description of an unusual case [Panatrofia di Gowers associata a sindrome da anticorpi antifosfolipidi primitiva: descrizione di un caso singolare]
No full textAn unusual case of Panatrophy of Gowers (PG) is here reported. PG is a rare disorder of skin and subcutaneous tissue, characterized by areas of atrophy in different parts of the integument, without any preceding inflammation. The etiopathogenesis is unknown, but the association of PG with multiple autoimmune diseases suggests an immunologic mechanism. A 49 years old woman, affected by PG since 1990, was admitted to our Institute in december 1993, because of a progressive development of arthralgias and myalgias, dyspnoea, vertigo, derangement and thrombophlebitis. The clinical features, the instrumental and biochemical investigations, in particular the positivity of antiphospholipid antibodies, allowed the diagnosis of primary antiphospholipid syndrome (APS). The term of primary APS has been introduced as a means of categorizing and studying these patients who do not have any feature of systemic lupus erythematosus or any other well defined disease. The feature of the antiphospholipid syndrome - arterial and venous thrombosis, livedo, strokes, migraine, recurrent abortions, occasional thrombocytopenia - have gradually expanded to embrance many specialities: nephrology (glomerular thrombosis), psychiatry (multi-infarct dementia), orthopedics (avascular necrosis), gastroenterology (Budd-Chiari Syndrome), endocrinology (Addison's disease), cardiology (valvular disease, pulmonary hypertension). The association of APS and PG is not reported in literature; so this case appears particulary interesting and suggests the possibility that PG can represent a clinical manifestation of a systemic vasculitis
Cerebrotendinous xanthomatosis. A case report [Xantomatosi cerebrotendinea. Presentazione di un caso]
No full textWe describe a patient with cerebrotendinous xanthomatosis (CTX) who saw a Rheumatologist because of joint and muscle pain in the lower limbs. Clinical examination did not reveal any classic joint disease; however, tendon lesions and clumsy gait were noted. The patient presented with a swollen Achilles tendon bilaterally and a parapareto-spastic gait; Babinski sign was positive on the right side, and hyperreflexia of both lower limbs could be demonstrated. As bilateral cataracts were present, we have interpreted the aforementioned signs as CTX with spinal involvement; mean plasma cholesterol was increased, thus confirming the diagnosis. The primary biochemical abnormality of this disease is a defect in the synthesis of bile acids; therefore, chenodeoxycholic acid (CDCA) has been tried, and beneficial effects following CDCA treatment, especially in the early stages of CTX, have been reported in the literature. We report this case because of the severity and the rarity of this disease, and also because of its hereditary transmission. Our aim is to underline the need of a precocious diagnosis, in order to prevent a further progression of the disease; this therapeutic goal can now be achieved, thanks to the therapeutic regimens recently develope
Epstein-Barr virus infection in sinonasal non-Hodgkin's lymphomas
No full textSinonasal non-Hodgkin's lymphomas (SNHLs) of B- or T-cell immunophenotype have been associated with Epstein-Barr virus (EBV) infection of neoplastic lymphoid tissue. Nine SNHLs were investigated using immunohistochemistry, the polymerase chain reaction (PCR) for EBV genome and in situ hybridization (ISH) for EBV encoded RNAs (EBER), immunoglobulin (CI-gHR) and clonal T-cell receptor (CTC beta R) gene rearrangements. Eight cases were diagnosed as peripheral pleomorphic T-cell lymphomas (pPTCL). PCR showed the presence of EBV genome in eight cases; ISH for EBER led to the detection of positive cells in five cases. Late membrane protein (LMP) immunostaining was observed in three cases. No EBV positivity has been detected in control cases. The frequent association with EBV infection in the cases illustrated confirms the previous suggestions that EBV may have a role in the genesis of lymphomas of the sinonasal region
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Epstein-Barr virus and gastric cancer: data and unanswered questions
No full textSixty‐five unselected cases of gastric cancer have been analysed for EBV DNA by polymerase chain reaction, in situ hybridization and immunohistochemistry for CD21 antigen expression. Four cases were found EBV‐positive by PCR, while ISH yielded positive results in 3 of these cases, demonstrating EBV in the nuclei of cancerous cells. CD21 antigen was expressed in cancerous cells in all 3 ISH‐positive cases. All the EBV‐positive cancers of the present series were poorly to moderately differentiated adenocarcinomas with prominent lymphoid infiltration. These results are discussed also on the basis of the literature. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Compan
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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