1,721,003 research outputs found
Comfort and environmental quality for school buildings: from energy audits to technological rehabilitation design
No full textNotizie sul consolidamento dei mosaici absidali di Torcello
No full textAtti del convegno ICCROM in Aquilei
Architettura fortificata e paesaggio: la destinazione museale per la valorizzazione della Fortezza di Cortona, in M. Fumo, G. Ausiello (a cura di), Riconoscere e far riconoscere i paesaggi fortificati. Recognizing and Making Known Fortified Landscapes, Edizioni Luciano, Napoli 2019, pp. 479-484 (ISBN: 978 88 6026 257 8; ISSN on-line editon: 2420 8213).
No full textIschia: da Castel Gerone a Castello Aragonese. Una fortificazione privata per la cultura
No full textIl cosiddetto Castello Aragonese di Ischia, le cui origini risalgono al V secolo a.C. - all’epoca di Gerone I, che fonda sull’isolotto la città di Geronda denominata anche Castel Gerone - costituisce l’isola nell’isola. Un maniero fortificato che per molti secoli ha rappresentato il nucleo delle attività non solo d’Ischia ma anche dell’intero territorio napoletano, per le sue valenze di “Forte” nel mare. Nei secoli è stato dimora privilegiata degli Angiò e degli Aragonesi, ospitando persino la Cattedrale e il palazzo Vescovile. Divenne il riparo per i profughi dei moti della repubblica Partenopea del 1799 e carcere durante le guerre d’indipendenza, e, nel 1860 monumento nazionale. Una storia articolata e complessa fino all’abbandono nel 1880 e alla vendita dallo Stato ai privati nel 1911. Al di là dei molteplici valori espressi dalle sue architetture di carattere difensivo militaresco, religioso-monastico, artistico-culturale, antropologico, l’intero complesso oggi rappresenta un caso virtuoso di bene culturale privatizzato. Il contributo si propone di offrire una lettura sintetica delle importanti stratificazioni storiche che costituiscono il palinsesto-Castello e il passaggio dallo Stato ai privati con la gestione dello stesso come modello esemplare per la conoscenza, la conservazione, la rifunzionalizzazione e la valorizzazione di un bene che per caratteristiche morfologiche, storiche, naturalistiche e paesaggistiche rappresenta un unicum. Il contributo, inoltre, vuole soffermarsi sulla procedura attivata nel 2009 dai proprietari, in collaborazione con associazioni culturali e professionali, per un concorso di idee - iniziativa che ha richiamato l’attenzione di personaggi da molte località europee - che aveva come scopo la riconfigurazione della antica Cattedrale di origine gotiche, con strutture aragonesi e barocche, oggi a stato di rudere dopo il bombardamento del 1809 da parte della flotta siculo-inglese guidata da Leopoldo di Borbone principe di Salerno
Leg ulcer in Werner syndrome (adult progeria): a case report
Full text linkWerner syndrome (WS; MIM#277700) or adult progeria, is a rare disease, associated with mutations of a single gene (RECQL2 or WRN), located on chromosome 8 (8p12). It codes a DNA-helicase, whose defects cause genomic instability. The highest incidences are reported in Japan and Sardinia (Italy). On this major island of the Mediterranean Basin, the WS cases have been observed in the northern areas. The authors describe the apparently first case reported in southern Sardinia, a 51-year-old woman, who was born in and resides in the province of Cagliari. She presented with a 9-year history of an intractable leg ulcer and other characteristic symptoms, including "bird-like" face, high-pitched voice, premature greying, short stature, abdominal obesity in contrast with thin body type, scleroderma-like legs, decreased muscle mass, diabetes, atherosclerosis, and premature menopause. A specialized genetic Institute of Research (IRCCS-IDI, Rome) confirmed the clinical diagnosis. There is no cure or specific treatment and patients must be periodically screened for an increased risk of cardiovascular and cerebrovascular disease and malignancies. Among the many findings, leg ulcers significantly affect the patient's quality of life. This problem may send the patient to the dermatologist, who finally suspects the diagnosis. Poor response to medical treatment may require aggressive repeated surgery, with poor or temporary results
Necrobiotic xanthogranuloma [XANTOGRANULOMA NECROBIOTICO] (1995) Giornale Italiano di Dermatologia e Venereologia, 130 (3), pp. 217-219
No full textDigital myxoid cysts: 12-year experience from two Italian Dermatology Units
No full textAIM AND METHODS:
Digital mucous cysts (DMCs) are benign, translucent, fluid-filled asymptomatic, slow-growing, dome-shaped nodules overlying a joint or tendon sheath on the distal dorsal side of the fingers or, more rarely, on the toes. They are degenerative in nature and are often associated with interphalangeal joint arthritis. Although DMCs are usually solitary, multiple cysts have been observed to develop simultaneously. They can sometimes be painful, confer a reduction in motility, and cause weakness and deformity in the nails. Spontaneous regression is rare, and intervention using surgical or non-surgical treatment is advisable. We analysed 53 DMCs of 51 patients treated in two Italian Dermatology Units between January 2004 and March 2015. The aim of this study was to evaluate the most salient clinical, histopathological and dermoscopic features, in addition to the response to treatment. We then compared the data to assess whether the histological type (ganglion-type or focal dermal mucinosis-type) or immunohistochemical phenotype of DMCs is correlated with the likelihood of relapse.
RESULTS AND CONCLUSIONS:
All the patients have been treated with simple surgical excision with a cure rate of 72.6% at a mean recurrence time of 160 days with a mean follow-up of 3.6 years. Histopathological examination, performed in 11 out of the 53 cysts, revealed seven cases of ganglion-type cysts and four cases of focal cutaneous mucinosis-type cysts. No correlation was detected between histopathological type and recurrence. Digital dermoscopy confirmed the pattern recently reported in the literature, providing confidence in the clinical diagnosis and reducing the need for pre-operative radiography or ultrasound imaging
A nose for trouble.
No full textA 63‐year‐old Caucasian non‐smoker presented with
purplish, firm, slowly growing plaques on the nose,
of 20 years duration. The bigger one involved the
upper part of the nose in its entirety [Figure 1], while
there were smaller ones on the left and right cheek. All
the plaques were asymptomatic and did not worsen
after sunlight exposure. His past medical history
was unremarkable. Hematological and biochemical
parameters were within normal limits. Histological
examination revealed a diffuse mid‐dermal cellular
infiltrate composed of neutrophils, eosinophils,
plasma cells, and lymphocytes. A narrow Grenz
zone was present. In the lower part of the reticular
dermis, the mixed infiltrate was intermingled with
a massive deposition of fascicled pattern collagen
fibers and spindle cell
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