1,720,981 research outputs found
Bullous Pemphigoid and Neurologic Diseases: Toward a Specific Serologic Profile?
No full textBACKGROUND: The association of bullous pemphigoid (BP) and neurologic disease (ND) has been proven. OBJECTIVE: To investigate the presence of specific markers for the association between BP and ND. METHOD: A total of 47 patients with PB, at the onset of the disease, were retrospectively recruited from January 2015 to October 2017 in a single center (Dermatology Unit, University of Bari "Aldo Moro", Bari, Italy). RESULTS: We have found an association between BP, ND and specific serologic profile characterized by higher levels of anti-BP180 and anti-BP230 (t(45)=2.319, p=0.025 and t(45)= 2.486, p=0.017, respectively), as compared to BP patients without ND. Furthermore, the univariate analysis revealed a significant association between ND and anti-BP230 positivity (P= 0.043). In detail, we observed a 4-time increased risk to have ND in BP patients showing anti-BP230 positivity. CONCLUSION: BP230 (BPAG1) is a member of the plakine family that links hemidemosomes to keratin filaments, being expressed at neuronal level. Thus, we hypothesized that alterations induced in ND could lead to the impairment of the "immune privilege", thus provoking the exposition of BP230 neuronal isoform
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Espressione di una proteina della famiglia delle catenine, p120cat, in linee cellulari di carcinoma del cavo orale.
No full textCadherins expression as a tool to detect cancer progression towards a metastatic phenotype
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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