1,460 research outputs found

    sj-docx-1-tae-10.1177_20420188221099349 – Supplemental material for Perioperative glycemic status is linked to postoperative complications in non-intensive care unit patients with type-2 diabetes: a retrospective study

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    Supplemental material, sj-docx-1-tae-10.1177_20420188221099349 for Perioperative glycemic status is linked to postoperative complications in non-intensive care unit patients with type-2 diabetes: a retrospective study by Takeshi Oba, Mototsugu Nagao, Shunsuke Kobayashi, Yuji Yamaguchi, Tomoko Nagamine, Kyoko Tanimura-Inagaki, Izumi Fukuda and Hitoshi Sugihara in Therapeutic Advances in Endocrinology and Metabolism</p

    Diaphragmatic excursion is correlated with the improvement in exercise tolerance after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease

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    近畿大学Kindai University博士(医学)主査:光冨徹哉 教授  学内授与番号:医第1377号 Masashi Shiraishi, Yuji Higashimoto, Ryuji Sugiya, Hiroki Mizusawa, Yu Takeda, Shuhei Fujita, Osamu Nishiyama, Shintarou Kudo, Tamotsu Kimura, Yasutaka Chiba, Kanji Fukuda, Yuji Tohda & Hisako Matsumoto "Diaphragmatic excursion is correlated with the improvement in exercise tolerance after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease" Respiratory Research volume 22, Article number: 271 (2021) https://doi.org/10.1186/s12931-021-01870-1 掲載application/pdfdoctoral thesi

    Constraints on the Level and Efficient Use of Labor in Japan

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    We examine a number of personnel practices, laws and regulations that lower the supply of labor in the Japanese economy. Broadly speaking, there are two kinds of impediments, those that restrict the movement of labor between firms, and those that discourage women from participating to a greater extent. Using other OECD countries and especially the United States as a benchmark, we estimate that removal of these barriers would increase the productive labor supply in Japan by some 13 to 18 percent and thus could raise the potential growth rate of the Japanese economy by roughly 1% per annum over a ten-year period.

    Abstract: New Seminar Series for Future Teachers (a series of 8 books)

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    Book Title: New Seminar Series for Future Teachers (a series of 8 books) Authors: ARAI, Yasuyuki; UENO, Kozaburo; SHIMIZU, Kazuhiko; KUBOTA, Shinji; TANAKA, Toji; OHTAKA, Izumi; ISHIKUMA, Toshinori; SHOJI, Ichiko; TSUKADA, Yasuhiko; IDA, Yoshiyasu; USHIRO, Yuji; SHIMIZU, Yoshinori; SAKURAI, Shigeo; MORO, Yuji; FUKUDA, Hiroshi; YOSHIDA, Takeo Publisher: Kyodo Shuppan Co., Ltd. Year: 2012, March - 2014, May 新教職教育講座 / 新井保幸, 上野耕三郎, 清水一彦, 窪田眞二, 大髙 泉, 田中統治, 石隈利紀, 庄司一子, 清水美憲, 櫻井茂男, 茂呂雄二, 福田 弘, 吉田武男編 2012年3月~2014年5月の英文アブストラクトである

    新教職教育講座

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    Book Title: New Seminar Series for Future Teachers (a series of 8 books) Authors: ARAI, Yasuyuki; UENO, Kozaburo; SHIMIZU, Kazuhiko; KUBOTA, Shinji; TANAKA, Toji; OHTAKA, Izumi; ISHIKUMA, Toshinori; SHOJI, Ichiko; TSUKADA, Yasuhiko; IDA, Yoshiyasu; USHIRO, Yuji; SHIMIZU, Yoshinori; SAKURAI, Shigeo; MORO, Yuji; FUKUDA, Hiroshi; YOSHIDA, Takeo Publisher: Kyodo Shuppan Co., Ltd. Year: 2012, March - 2014, May 新教職教育講座 / 新井保幸, 上野耕三郎, 清水一彦, 窪田眞二, 大髙 泉, 田中統治, 石隈利紀, 庄司一子, 清水美憲, 櫻井茂男, 茂呂雄二, 福田 弘, 吉田武男編 2012年3月~2014年5月の英文アブストラクトである。othe

    Human Capital and Economic Growth : Dynamic Implications of Insider-outsider Problem for Macroeconomics

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    This paper considers a dynamic model with human capital accumulation, for which both firm-specific skills and general skills are sources of growth. We analyze how the existence of firm-specific skills changes the effects of productivity shocks on economic growth. It is well known that the insider-outsider problem can cause employment inertia in the macro economy because workers with firm-specific skills (insiders) face the hold up problem. However, most previous studies have been static in nature, so that they have paid little attention to dynamic interactions between firm-specific skills and general skills during the adjustment to the new steady state. This paper considers dynamic models that involve creation of human capital from both firm-specific skills and general skills. We show that the insider-outsider problem that is generated through the creation of firm-specific skills can cause a dramatic decline in the youth labor force during a transition path to the steady state. We also show that the problem may result in a temporary economic downturn even if the shock is positive. In Japan, since the mid-1990s, there has been a dramatic increase in the unemployment rate and a substantial decrease in the working population ratio together with increased irregular employment among young people. By analyzing firm-specific human capital as an engine of economic growth, this paper shows that these trends are consistent with our dynamic model. It also demonstrates that the productivity shocks might explain recent dramatic declines in youth employment and temporary declines in growth rates.firm-specific human capital, labor markets, insider-outsider problem

    Hematopoietic stem and progenitor cells integrate microbial signals to promote post‐inflammation gut tissue repair

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    Bone marrow (BM)-resident hematopoietic stem and progenitor cells (HSPCs) are often activated following bacterial insults to replenish the host hemato-immune system, but how they integrate the associated tissue damage signals to initiate distal tissue repair is largely unknown. Here, we show that acute gut inflammation expands HSPCs in the BM and directs them to inflamed mesenteric lymph nodes through GM-CSFR activation for further expansion and potential differentiation into Ly6C(+)/G(+) myeloid cells specialized in gut tissue repair. We identified this process to be mediated by Bacteroides, a commensal gram-negative bacteria that activates innate immune signaling. These findings establish cross-organ communication between the BM and distant inflamed sites, whereby a certain subset of multipotent progenitors is specified to respond to imminent hematopoietic demands and to alleviate inflammatory symptoms.

    Author response image 1.

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    Neurotransmitter is released at synapses by fusion of synaptic vesicles with the plasma membrane. To sustain synaptic transmission, compensatory retrieval of membranes and vesicular proteins is essential. We combined capacitance measurements and pH-imaging via pH-sensitive vesicular protein marker (anti-synaptotagmin2-cypHer5E), and compared the retrieval kinetics of membranes and vesicular proteins at the calyx of Held synapse. Membrane and Syt2 were retrieved with a similar time course when slow endocytosis was elicited. When fast endocytosis was elicited, Syt2 was still retrieved together with the membrane, but endocytosed organelle re-acidification was slowed down, which provides strong evidence for two distinct endocytotic pathways. Strikingly, CaM inhibitors or the inhibition of the Ca2+-calmodulin-Munc13-1 signaling pathway only impaired the uptake of Syt2 while leaving membrane retrieval intact, indicating different recycling mechanisms for membranes and vesicle proteins. Our data identify a novel mechanism of stimulus-and Ca2+-dependent regulation of coordinated endocytosis of synaptic membranes and vesicle proteins

    N=2 supersymmetric dynamics for pedestrians

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    Understanding the dynamics of gauge theories is crucial, given the fact that all known interactions are based on the principle of local gauge symmetry. Beyond the perturbative regime, however, this is a notoriously difficult problem. Requiring invariance under supersymmetry turns out to be a suitable tool for analyzing supersymmetric gauge theories over a larger region of the space of parameters. Supersymmetric quantum field theories in four dimensions with extended N=2 supersymmetry are further constrained and have therefore been a fertile field of research in theoretical physics for quite some time. Moreover, there are far-reaching mathematical ramifications that have led to a successful dialogue with differential and algebraic geometry. These lecture notes aim to introduce students of modern theoretical physics to the fascinating developments in the understanding of N=2 supersymmetric gauge theories in a coherent fashion. Starting with a gentle introduction to electric-magnetic duality, the author guides readers through the key milestones in the field, which include the work of Seiberg and Witten, Nekrasov, Gaiotto and many others. As an advanced graduate level text, it assumes that readers have a working knowledge of supersymmetry including the formalism of superfields, as well as of quantum field theory techniques such as regularization, renormalization and anomalies. After his graduation from the University of Tokyo, Yuji Tachikawa worked at the Institute for Advanced Study, Princeton and the Kavli Institute for Physics and Mathematics of the Universe. Presently at the Department of Physics, University of Tokyo, Tachikawa is the author of several important papers in supersymmetric quantum field theories and string theory

    Seven connection patterns between the author research areas.

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    Seven connection patterns between the author research areas.</p
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