610 research outputs found

    Transcription dynamics of rice GIGANTEA modeled using GenomeBasedModel

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    This is an analysis example of the R package GenomeBasedModel. The package has been developed by the author for estimating parameters of arbitrary biological statistical models and effects of genome-wide SNPs on the parameters simultaneously by building prior distributions based on the SNPs for the parameters. Here transcription dynamics of rice GIGANTEA is modeled using the package. See also https://github.com/Onogi/GenomeBasedModel/ for the package

    Transcription dynamics of rice GIGANTEA modeled using GenomeBasedModel

    No full text
    This is an analysis example of the R package GenomeBasedModel. The package has been developed by the author for estimating parameters of arbitrary biological statistical models and effects of genome-wide SNPs on the parameters simultaneously by building prior distributions based on the SNPs for the parameters. Here transcription dynamics of rice GIGANTEA is modeled using the package. See also https://github.com/Onogi/GenomeBasedModel/ for the package

    Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

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    博士論文本文Full 以下に掲載:Plos ONE 7(9) pp.e43056-e43056 2012. Plos ONE. 共著者:Yuki Kita, Toshinari Takamura, Hirofumi Misu, Tsuguhito Ota, Seiichiro Kurita, Yumie Takeshita, Masafumi Uno, Naoto Matsuzawa-Nagata, Ken-ichiro Kato, Hitoshi Ando, Akio Fujimura, Koji Hayashi, Toru Kimura, Shuichi Kanek

    Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice

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    博士論文 要旨Abstract/本文Full 以下に掲載:Molecular Metabolism 49 pp.1-13 2021. Elsevier. 共著者:Nazmul Hasan,Naoto Nagata,Jun-Ichi Morishige,Md Tarikul Islam,Zheng Jing,Ken-Ichi Harada,Michihiro Mieda,Masanori Ono,Hiroshi Fujiwara,Takiko Daikoku,Tomoko Fujiwara,Yoshiko Maida,Tsuguhito Ota,Shigeki Shimba,Shuichi Kaneko,Akio Fujimura,Hitoshi And

    Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

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    金沢大学博士(医学)博士論文本文Full 以下に掲載:Plos ONE 7(9) pp.e43056-e43056 2012. Plos ONE. 共著者:Yuki Kita, Toshinari Takamura, Hirofumi Misu, Tsuguhito Ota, Seiichiro Kurita, Yumie Takeshita, Masafumi Uno, Naoto Matsuzawa-Nagata, Ken-ichiro Kato, Hitoshi Ando, Akio Fujimura, Koji Hayashi, Toru Kimura, Shuichi Kanekodoctoral thesi

    REVIEW OF: "Kawauchi Akio, Splitting a 4-manifold with infinite cyclic fundamental group, revised, J. Knot Theory Ramifications 22, No. 14, Article ID 1350081, 9 p. (2013)". [DE062730205]

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    In [Osaka J. Math. 31(3), 489-495 (1994; Zbl 0849.57018 )], the author stated that every closed connected orientable 4-manifold M with infinite cyclic fundamental group is TOP-split, i.e. it is homeomorphic to the connected sum (S1 × S3)#M1, M1 being a closed simply connected 4-manifold. However, in [Manuscr. Math. 93(4), 435-442 (1997; Zbl 0890.57034)], Hambleton and Teichner obtained a counterexample to the above general statement. In the paper under review, the author makes a revision and proves that TOP-splittability holds under the additional hypothesis that a finite covering of M is TOP-split. In particular, the original statement turns out to be true in the case of indefinite intersection form, as well as for any smooth spin 4-manifold (with infinite cyclic fundamental group). The proof of the revised statement makes use of notions developed in [Knots in Hellas 98, Ser. Knots Everything. 24 (World Scientific Publishing), 208-228 (2000; Zbl 0969.57020)] and [Atti Semin. Mat. Fis. Univ. Modena 48(2), 405-424 (2000; Zbl 1028.57019)], together with the key result - proved in [Osaka J. Math. 31(3), 489-495 (1994; Zbl 0849.57018 )] - that every closed connected orientable 4-manifold M with infinite cyclic fundamental group is homology cobordant to (S1 × S3)#M1. Consequences about surface-knots in S4 are also considered (see [J. Knot Theory Ramifications 4(2), 213-224 (1995; Zbl 0844.57020)])

    Environmental Taxes and Productivity: Lessons from Canadian Manufacturing

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    https://www.grips.ac.jp/list/jp/facultyinfo/yamazaki-akio/This paper investigates how environmental taxes affect manufacturing productivity by examining British Columbia’s revenue-neutral carbon tax. I develop a new hypothesis, the “Productivity Dividend Hypothesis,” to show that environmental taxes can positively affect productivity by recycling tax revenues to reduce corporate income taxes. This revenue-recycling increases investment and could raise productivity more than environmental taxes lower productivity by diverting resources from production. I evaluate this hypothesis using detailed confidential plant-level data. I find that the carbon tax lowers productivity, although this is offset to some extent by the revenue-recycling. For some plants, the policy generates a net gain in productivity.JEL Classification Codes: D22, H23, L6, Q5The author acknowledges generous funding from Productivity Partnership (PP) and Smart Prosperity Institute (SPI), supported by the Social Sciences and Humanities Research Council of Canada.technical repor

    Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice

    No full text
    金沢大学博士(医学)博士論文 要旨Abstract/本文Full 以下に掲載:Molecular Metabolism 49 pp.1-13 2021. Elsevier. 共著者:Nazmul Hasan, Naoto Nagata, Jun-Ichi Morishige, Md Tarikul Islam, Zheng Jing, Ken-Ichi Harada, Michihiro Mieda, Masanori Ono, Hiroshi Fujiwara, Takiko Daikoku, Tomoko Fujiwara, Yoshiko Maida, Tsuguhito Ota, Shigeki Shimba, Shuichi Kaneko, Akio Fujimura, Hitoshi Andodoctoral thesi

    Selenoprotein P as a diabetesassociated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

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    金沢大学博士(医学)博士論文本文Full 以下に掲載:Diabetologia 57(9) pp.1968-1976 2014.Springer. 共著者:Kazuhide Ishikura, Hirofumi Misu, Masafumi Kumazaki, Hiroaki Takayama, Naoto Matsuzawa-Nagata, Natsumi Tajima, Keita Chikamoto, Fei Lan, Hitoshi Ando, Tsuguhito Ota, Masaru Sakurai, Yumie Takeshita, Kenichiro Kato, Akio Fujimura, Ken-ichi Miyamoto, Yoshiro Saito, Satomi Kameo, Yasuo Okamoto, Yoh Takuwa, Kazuhiko Takahashi, Hiroyasu Kidoya, Nobuyuki Takakura, Shuichi Kaneko, Toshinari Takamuradoctoral thesi

    Selenoprotein P as a diabetesassociated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

    No full text
    博士論文本文Full 以下に掲載:Diabetologia 57(9) pp.1968-1976 2014.Springer. 共著者:Kazuhide Ishikura, Hirofumi Misu, Masafumi Kumazaki, Hiroaki Takayama, Naoto Matsuzawa-Nagata, Natsumi Tajima, Keita Chikamoto, Fei Lan, Hitoshi Ando, Tsuguhito Ota, Masaru Sakurai, Yumie Takeshita, Kenichiro Kato, Akio Fujimura, Ken-ichi Miyamoto, Yoshiro Saito, Satomi Kameo, Yasuo Okamoto, Yoh Takuwa, Kazuhiko Takahashi, Hiroyasu Kidoya, Nobuyuki Takakura, Shuichi Kaneko, Toshinari Takamur
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