228 research outputs found
Tecniche narrative nelle autobiografie italiane del Secondo Settecento
No full textThis Ph.D thesis analyses seven autobioraphies by italian writers, all born in in the Eighteenth century: Vittorio Alfieri, Carlo Goldoni, Lorenzo Da Ponte, Giacomo Casanova, Filippo Mazzei, Francesco Bal. It is divided in two parts: the first concerns with microtextuality aspects (incipit, explicit, dialogues, descriptions); the second deals with the macrotextuality ones (structures of time, structures of the plot). Besides evalutating in which ways the autobiographies organize their narration, the author compares them with Eighteenth Century italian novels and with other autobiographical works to see how much their structure is different
AUTHENTICITY CRITERIA IN CASTLES OF IVANO-FRANKIVSK REGION
No full text1- The information about castles can change during the time passing. It is important to verify what is authentic in the castles that are under research. 2-The author, based on the case studies about castles and after analyzing the best practices in Europe explores the verification of authenticity and define the fundamental criteria in conservation. Base of the found materials about castles in Ivano- Frankivsk region and taking into consideration the different interdisciplinary views on Conservation create a systematization of detected objects in Ivano – Frankivsk region by the time of their occurrence and the architectural and typological characteristics. It can help to define the authenticity criteria for Conservation of Castles in this area. 3- This criteria can help to define the method of preservation for each castle that was under this investigation. And set the authenticity criteria for Conservation of Castles in this region
Dolutegravir: clinical efficacy and role in HIV therapy.
No full textThe human immunodeficiency virus type-1 (HIV-1) integrase enzyme has recently emerged as a primary alternative target to block viral replication, and integrase strand transfer inhibitors (INSTIs) are now considered an alternative 'third agent' class of antiretroviral (ARV) drugs. Dolutegravir is the first next-generation INSTI showing some novel and intriguing characteristics: it has a favorable pharmacokinetic profile with a prolonged intracellular halflife, rendering feasible a once daily dosing without the need for pharmacokinetic boosting. Secondly, it is largely metabolized via uridine diphosphate glucuronosyltransferase-1A1 with a minor component of cytochrome P450 isoforms, thus allowing a low grade of drug-drug interactions, so that its metabolic profile consents co-administration with the majority of the other ARV drugs without dose adjustments. Lastly, but no less important, virological studies have clearly demonstrated that dolutegravir has a significant activity against HIV-1 isolates showing raltegravir and/or elvitegravir associated resistance mutations. The attributes of once daily administration and the potential to treat INSTI-resistant viruses make dolutegravir an interesting and promising new agent in the treatment of both naïve and experienced HIV-1 subjects. In this review, the main concerns on dolutegravir efficacy are focused through the analysis of the currently available data from clinical studies in naïve and experienced patients, evaluating its possible place within the anti-HIV-1 drug armamentarium. The development of newer once daily, single tablet coformulations improved drug adherence and maximized the success of ARV therapy. Pharmacokinetic studies and dose-ranging trials suggested that dolutegravir is a good candidate for a single tablet regimen in one or more new coformulated pills that will be available in the near future. © The Author(s), 2014
The Effect of Phacoemulsification on Intraocular Pressure in Eyes with Hyperfiltration Following Trabeculectomy: A Prospective Study
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Repository e front-end open-source per la conservazione di opere digitali
No full textCeris-CNR IT Office and Ceris-CNR Library are involved in a digitization project promoted by Bess (Electronic Library of Economic and Social Sciences in Piedmont Area) and commissioned to handle all the post-scan of the digitization.
This technical report analyzes the strategies adopted and the main open-source software used.
Ceris-CNR had to provide for the management of large volumes of data with the availability of space storage for the digitized works with characteristics of stability, versatility and dynamism. Ceris-CNR has deployed the software and server platforms of the repository, in a virtualized and redundant infrastructure. Ceris–CNR also take care of the design, development and management of the web portal (front-end) for the presentation, research and consulting data of the digitalized item
FABB Repository dal progetto al prototipo. Nuove forme di conservazione, condivisione e valorizzazione di opere digitali
No full textRT 03; FABB project (Famine and Feast, Fame e Abbondanza) has been committed by Fondazione CRT. This technical report analyzes the strategies adopted and the main open-source software used. Ircres-CNR has deployed the software and server platforms of the repository, in a virtualized and redundant infrastructure, it also take care of the design, development and management of the web portal (front-end) for the presentation, research and consulting data of the digitalized items (lyrics, lyrics text, interviews, books, poems)
Theodor W. Adorno e il concetto di seconda natura nel Doktor Faustus di Thomas Mann
No full text“Doktor Faustus” of Thomas Mann, as explained by its author, is a novel on German civilization in which music plays the role of paradigm. Nevertheless the author grasps a lot of quotations from different disciplines and topics, ― e.g., theology, policy, philosophy, music, chemistry ― with the aim of depicting the creation of a second nature in music according the rules of twelve-note composition established by Arnold Schoenberg. The starting point of this complicated narrative is the reinterpretation of Theodor W. Adorno’s “Philosophie der neuen Musik”, a book that inspired Mann in tracing the idea of “second nature” created by the composer Adrian Leverkühn. The article focuses on some keywords used in the famous novel, and taken from inorganic chemistry and geology, working as metaphors on the thin line between nature and nurture. This analogy is retraceable in the biography of Adrian Leverkühn, whose music is the result of a demiurgic, daemonic power he gained after his deal with the devil
Translations Facing Inwards: James VI/I’s Basilikon Doron
No full textFirst published in 1599, and thereafter subjected to very careful revision on the part of its author, and destined to become the protagonist of a most adventurous editorial history, the Basilikon Doron has always presented a serious puzzle to editors and textual critics. James VI of Scotland, a king with no little experience of writing, attempted with this treatise the impossible task of exerting total control on his published work, and this, coupled with the extraordinary political circumstances surrounding the appearance of this text, triggered its fascinating textual history. This results in a text with many variants and translations, and the first is the work of its author, who transposes the original, heavily Scottish text into a wholly Anglicized version, ready for a publication that would be associated with the new King of England. The text immediately became the subject of discussion in Europe, and unauthorised new editions and translations began to appear, much to James’s annoyance.
The present chapter analyses two translations that are deeply embedded in James’s own preoccupation with the circulation of his political work: one is the King’s own transposition of the text from Middle Scots to English; the other is the Italian translation undertaken by John Florio, and surviving in manuscript. Obsessively faithful to the 1603 printed version, Florio’s translation does not look outward, at a possible Italian readership of the treatise; it rather attempts to reflect further glory on James’s text, closely imitating all its characteristics and explicitly proposing itself as a homage to a king that subsumes in himself all political thought: the centre towards which all advice writing converges, and from which it will spring again in different idioms
Quantum enhanced non-interferometric quantitative phase imaging
No full textQuantum entanglement and squeezing have significantly improved phase
estimation and imaging in interferometric settings beyond the classical limits.
However, for a wide class of non-interferometric phase imaging/retrieval
methods vastly used in the classical domain e.g., ptychography and diffractive
imaging, a demonstration of quantum advantage is still missing. Here, we fill
this gap by exploiting entanglement to enhance imaging of a pure phase object
in a non-interferometric setting, only measuring the phase effect on the
free-propagating field. This method, based on the so-called "transport of
intensity equation", is quantitative since it provides the absolute value of
the phase without prior knowledge of the object and operates in wide-field
mode, so it does not need time-consuming raster scanning. Moreover, it does not
require spatial and temporal coherence of the incident light. Besides a general
improvement of the image quality at a fixed number of photons irradiated
through the object, resulting in better discrimination of small details, we
demonstrate a clear reduction of the uncertainty in the quantitative phase
estimation. Although we provide an experimental demonstration of a specific
scheme in the visible spectrum, this research also paves the way for
applications at different wavelengths, e.g., X-ray imaging, where reducing the
photon dose is of utmost importance.Comment: arXiv admin note: text overlap with arXiv:2109.1009
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