2,090,419 research outputs found

    Eksistensi Seni Pertunjukan Jipeng Grup Pusaka Tiga Saudara Kalisari Pasar Rebo Jakarta Timur

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    Penelitian ini dilakukan untuk mendapatkan hasil yang akurat mengenai keberadaan dan masalah-masalah yang dihadapi serta usaha yang dilakukan Grup Pusaka Tiga Saudara untuk mengatasi masalah yang dihadapi dalam mengembangkan kesenian Jipeng di Kalisari Pasar Rebo Jakarta Timur. Penelitian ini menggunakan metode kualitatif deskriptif sebagai teknik pengumpulan data yang berfokus pada Eksistensi Seni Pertunjukan Jipeng Grup Pusaka Tiga Saudara Kalisari Pasar Rebo Jakarta Timur. Dengan observasi, studi pustaka, dan wawancara sebagai teknik pengumpulan data. Proses observasi dilakukan pada bulan Oktober 2017 - Desember 2018 di Desa Kalisari, Kecamatan Cijantung, Jakarta Timur. Dari hasil penelitian diperoleh data bahwa eksistensi seni pertunjukan Jipeng grup Pusaka Tiga Saudara masih eksis walaupun frekuensi pementasannya mengalami penurunan. Dahulu tampil sebanyak 25 kali dalam sebulan namun sekarang hanya 2 kali dalam setahun dikarenakan ada beberapa masalah. Dalam penelitian ini ditemukan lagu-lagu yang digunakan dalam pertunjukan Jipeng yaitu bernama Mars Selamat Datang,Mars Jinekuda,Mars Porka,Mars dodoledet, Sirih kuning, Jali-jali, Kicir-kicir, Lenggang kangkung, Kacamata riben, Geboy, Kabupatenan, Tepangsono, Gaplek, Kidung selamat datang, dan Ucingucingan.Masalah yang dihadapi adanya persaingan dengan musik modern seperti dangdut, pop yang lebih banyak peminatnya, minimnya lahan juga membuat pertunjukan Jipeng sulit ditampilkan. Usaha yang dilakukan oleh grup Pusaka Tiga Saudara memperkenalkan dan melatih anak cucu mereka untuk regenerasi pemain, usaha dari pemerintah adalah mendukung kesenian Jipeng untuk terus dilestarikan dengan cara memberikan kesempatan mereka untuk tampil di daerahdaerah khususnya Jakarta. Masyarakat desa Kalisari Jakarta Timur juga mengharapkan kesenian Jipeng ini terus berkembang dan tidak mengalami kepunahan Implikasi penelitian ini yang menyatakan bahwa keberadaan Jipeng mengalami penurunan. Agar tidak punah maka peneliti berharap hasil penelitian ini bisa diimplementasikan dalam salah satu kegiatan ekstrakulikuler di sekolah dari tingkat dasar agar kesenian Jipeng tetap terjaga kelestariannya sehingga kesenian ini bisa diketahui dan dipelajari oleh generasi muda khususnya masyarakat Betawi.

    Kinetic modeling of 5-FU-loaded SLNs.

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    The present study aimed to prepare solid lipid-based nanoparticles (SLNs) using Precirol® ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant respectively, and SLNs-derived gel for sustained delivery, enhanced in-vitro cytotoxicity, enhanced cellular uptake of 5-FU and enhanced permeation of 5-FU across the skin. The 5-FU-loaded SLNs were prepared by the hot melt encapsulation method and converted into SLN-derived gel using a gelling agent (Carbopol 940). The 5-FU-loaded SLNs had a particle size in the range of 76.82±1.48 to 327±4.46 nm, zeta potential between -11.3±2.11 and -28.4±2.40 mV, and entrapment efficiency (%) in range of 63.46±1.13 and 76.08±2.42. The FTIR analysis depicted that there was no chemical interaction between 5-FU and formulation components. Differential scanning calorimetric analysis showed thermal stability of 5-FU in the nanoparticles and powdered X-ray diffraction analysis revealed successful incorporation of 5-FU in nanoparticles. The in-vitro release study of 5-FU-loaded SLNs showed biphasic release behavior with initial burst release followed by sustained release over 48 hr. The 5-FU-loaded SLNs showed a greater cytotoxic effect on skin melanoma (B16F10 cells) and squamous cell carcinoma (A-431 cells) as compared to free 5-FU drug solution after 48 hr. Flow cytometry and fluorescence microscopy displayed enhanced quantitative and qualitative cellular uptake of SLNs. The SLNs formulation showed acceptable safety and biocompatible profile after an acute toxicity study in Wistar rats. Moreover, ex-vivo permeation studies depicted 2.13±0.076 folds enhanced flux of 5-FU-loaded SLN derived gel compared to 5-FU plain gel, and skin retention studies revealed target efficiency (%) 2.54±0.03 of 5-FU-loaded SLN derived gel compared to 5-FU plain gel.</div

    Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial

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    Oral capecitabine (Xeloda&lt;sup&gt;&#174;&lt;/sup&gt;) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer. Oxaliplatin-based therapy is becoming standard for Dukes' C colon cancer in patients suitable for combination therapy, but is not yet approved by the UK National Institute for Health and Clinical Excellence (NICE) in the adjuvant setting. Adjuvant capecitabine is at least as effective as 5-fluorouracil/leucovorin (5-FU/LV), with significant superiority in relapse-free survival and a trend towards improved disease-free and overall survival. We assessed the cost-effectiveness of adjuvant capecitabine from payer (UK National Health Service (NHS)) and societal perspectives. We used clinical trial data and published sources to estimate incremental direct and societal costs and gains in quality-adjusted life months (QALMs). Acquisition costs were higher for capecitabine than 5-FU/LV, but higher 5-FU/LV administration costs resulted in 57% lower chemotherapy costs for capecitabine. Capecitabine vs 5-FU/LV-associated adverse events required fewer medications and hospitalisations (cost savings £3653). Societal costs, including patient travel/time costs, were reduced by &gt;75% with capecitabine vs 5-FU/LV (cost savings £1318), with lifetime gain in QALMs of 9 months. Medical resource utilisation is significantly decreased with capecitabine vs 5-FU/LV, with cost savings to the NHS and society. Capecitabine is also projected to increase life expectancy vs 5-FU/LV. Cost savings and better outcomes make capecitabine a preferred adjuvant therapy for Dukes' C colon cancer. This pharmacoeconomic analysis strongly supports replacing 5-FU/LV with capecitabine in the adjuvant treatment of colon cancer in the UK

    PENERAPAN BLENDED LEARNING DALAM PEMBELAJARAN TARI JIPENG UNTUK MENINGKATKAN KEMAMPUAN SISWA BERKREASI TARI

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    Kemajuan teknologi menuntut sekolah dan guru melaksanakan kegiatan pembelajaran dengan memadukan pembelajaran tatap muka dan pemanfaatan teknologi yang disebut blended learning. Tujuan penelitian ini ialah untuk meningkatkan kemampuan siswa dalam berkreasi tari pada kelas XI MIPA 1 di SMA Negeri 1 Jampangkulon. Pendekatan yang digunakan dalam penelitian ini adalah mix method exploratory sequensial, yaitu penelitian kualitatif diikuti dengan pendekatan kuantitatif. Penelitian kualitatif menggunakan metode deskriptif analisis untuk meneliti tari Jipeng. Penelitian kuantitatif menggunakan pre-experimental design, untuk meneliti pembelajaran tari. Teknik pengumpulan data dilakukan dengan cara wawancara, observasi, studi dokumentasi dan tes. Teknik analisis data dalam penelitian kualitatif menggunakan uji-t. Hasil penelitian tentang tari Jipeng menggambarkan gerak yang spontan, namun memiliki struktur sajian yang jelas, diiringi musik gamelan dan tanji yang dipertunjukan pada ritual ngaseuk yang fungsingnya untuk hiburan. Tari Jipeng ini diterapkan dalam pembelajaran tari dengan menggunakan blended learning yang menghasilkan peningkatan kemampuan siswa dan berkreasi tari. Hal ini dibuktikan dengan uji t, dengan hasil peningkatan berkreasi siswa yang signifikan thitung 5.111˃ ttabel 2.037. Penelitian ini memiliki implikasi dalam perubahan strategi pembelajaran dari yang konvensional ke blended learning dengan pemanfaatan teknologi. Advances in technology require schools and teachers to carry out learning activities by combining face-to-face learning and the use of technology, which is called blended learning. The purpose of this research is to increase the ability of students in creating dance in class XI MIPA 1 at SMA Negeri 1 Jampangkulon. The approach used in this study is a sequential exploratory mix method, namely qualitative research followed by a quantitative approach. Qualitative research uses descriptive analysis method to examine Jipeng dance. Quantitative research uses a pre-experimental design, to examine dance learning. Data collection techniques were carried out by means of interviews, observation, documentation studies and tests. Data analysis techniques in qualitative research use the t-test. The results of research on the Jipeng dance describe spontaneous movements, but have a clear presentation structure, accompanied by gamelan music and tanji which are performed in the ngaseuk ritual whose function is for entertainment. This Jipeng dance is applied in dance learning using blended learning which results in increased student ability and dance creation. This is evidenced by the t test, with the results of a significant increase in student ability tcount 5.111˃ ttable 2.037. This research has implications for changing learning strategies from conventional to blended learning with the use of technology

    O kung Fu e o desenvolvimento infantil : desenvolvimento motor

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    Este trabalho busca elementos para verificar a ligação do Kung Fu, uma arte marcial chinesa, com o desenvolvimento motor infantil, baseando-se no conceito do desenvolvimento motor de GALLAHUE, D. L.; OZMUN, J. C e MEINEL, K., e assim poder associar estes conceitos a pratica desta, que atualmente é uma das artes marciais mais praticadas no mundo. Mas antes de apresentar o desenvolvimento motor, passa-se por uma revisão da história do Kung Fu, e uma revisão sobre o desenvolvimento, para que se possa desenvolver com clareza a idéia da ligação das duas coisas. Durante a pesquisa foi realizado como forma de busca de dados, um sistema de diário de observação de alunos praticantes de Kung Fu em diversos níveis de aprendizagem e treinamento, respeitando a faixa etária proposta pelo trabalho, para poder apresentar conclusões consistentes. Sem aprofundar-se no tipo de treinamento realizado e nos estilos existentes da modalidade esportiva, mas se atentando exclusivamente as crianças no treinamento, com os dados coletados, foi possível observar uma grande relação entre o Kung Fu e a melhora do desenvolvimento de capacidades como coordenação motora geral, equilíbrio, lateralidade, noção de direita e esquerda, posição e sentido.This paper searches for elements to verify the connection of Kung Fu, a Chinese martial art, with the motor development of children, based on the concept of motor development of GALLAHUE, D. L.; OZMUN, J. C e MEINEL, K., and this way be able to associate these concepts to it, which is currently one of the most practiced martial arts in the world. But before presenting the motor development, it will go through a review of the history of Kung Fu, and a review about the development, so that it can develop a clear idea of the connection of both things. During the research it was conducted as a way of data searching, a system of observation journal of students practicing Kung Fu at different levels of learning and training, respecting the age proposed for the work, to present consistent conclusions. Without going too deep into the kind of training conducted and in the different existing styles of the sport, but exclusively paying attention to the children in training, with the collected data, it was possible to observe a strong relation between Kung Fu and the improvement of capacities as general motor coordination, balance, laterality, sense of right and left, position and direction

    Kung-Fu Exhibition program, May 5, 1984

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    1984Established in 1963, the Seattle Kung Fu Club offers traditional martial arts classes for adults and children in Seattle's International District neighborhood. The program pictured here is from a Kung-Fu exhibition presented by the club on May 5, 1984, at the Seattle Center Arena (now KeyArena)"Caption information source: https://www.seattlekungfuclub.com.1 program (28 p." 8.5 x 11 in
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