163 research outputs found
Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Yang, Jinling, Fu, Wenwei, Xiang, Qian, Tang, Yuexun, Wu, Rong, Zheng, Changwu, Lu, Yue, Zhou, Hua, Xu, Hongxi (2020): Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha. Phytochemistry (112329) 174: 1-10, DOI: 10.1016/j.phytochem.2020.112329, URL: http://dx.doi.org/10.1016/j.phytochem.2020.11232
Fig. 2. Observed 1H–1H in Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha
Fig. 2. Observed 1H–1H COSY (blue lines) and Key HMBC (red arrows) correlations of 1–10. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Yang, Jinling, Fu, Wenwei, Xiang, Qian, Tang, Yuexun, Wu, Rong, Zheng, Changwu, Lu, Yue, Zhou, Hua & Xu, Hongxi, 2020, Cytotoxic xanthone derivatives from the twigs of Garcinia oligantha, pp. 1-10 in Phytochemistry (112329) 174 on page 3, DOI: 10.1016/j.phytochem.2020.112329, http://zenodo.org/record/829499
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Biomechatronics: Harmonizing Mechatronic Systems with Human Beings
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
Consumer preference and willingness to pay for red, high-antioxidant sweet corn
Developing environmentally sustainable and economically productive crop varieties is necessary to preserve the natural resources being steadily utilized in production agriculture. Moreover, these new varieties should be marketable to consumers to ensure their long-term fiscal viability and secure a position as combatants of environmental degradation. However, limited research has explored the correlation between sustainable corn production and consumers’ willingness to pay, especially regarding new varieties marketed for consumption. Using the double-bounded contingent valuation method and a binary logit model to analyze the results of a nationwide survey, this paper aims to determine (i) if consumers exhibit a willingness to pay for a new corn variety that is nutrient dense and has a unique color variation (ii) evaluate the characteristics associated with individuals who are willing to purchase the new variety, and how these consumers differ demographically, socioeconomically, and geographically, and (iii) determine if taste and texture of the new corn variety affects willingness to pay levels and the likelihood of purchase.Restricted until 06/2023. To request the author grant access, click on the PDF link to the left
IPRs, Public Health, and International Trade: An International Law Perspective on the TRIPS Amendment
This article critically examines the dynamics between public health, intellectual property, and international trade in the context of the TRIPS Amendment and its theoretical implications in international law. The article suggests that international efforts in the TRIPS 2003 Waiver and 2005 Amendment addressing public health concerns have not been very successful due to the birth defect of TRIPS, i.e., hoping a private-rights-in-nature regime could accommodate public interests in health concerns. TRIPS' birth defect further reveals itself in post-TRIPS development and contributed to the failure of the TRIPS Waiver and Amendment due to the resulting practice fragmentation and procedural hurdles in domestic compulsory licensing administration. Moreover, the TRIPS Amendment raised a fundamental theoretical issue, i.e., how the WTO as an international organization in public international law can regulate compulsory licensing of intellectual property rights as private rights - in particular the proprietary right to remuneration - while recognizing that TRIPS grants no positive rights. The paper suggests that the key to the issue is the treatment of private rights in public international law. It is submitted that the TRIPS Amendment has no legal basis in international law due to its unwarranted intrusion into members' domestic affairs and individuals' private proprietary rights. The article thus calls for alternative thinking about the TRIPS Amendment, in particular to leave administration of compulsory licensing fully with domestic authorities as it is in the Paris [email protected]
Adherence to dietary recommendations and chronic kidney disease : insights into disease onset and progression
Background: CKD is becoming a major global health concern, marked by a gradual, permanent decline in kidney function, constrained treatment possibilities, and rising healthcare expenses. Dietary modifications play an important role in managing risk factors for CKD incidence and in slowing its progression, and these adjustments should be based on dietary guidelines. However, current guidelines predominantly rely on Western-based evidence, leaving critical gaps in protein types, dietary patterns, and cultural adaptability. Given the significant differences in food structure and dietary habits between China and many Western countries, it is essential to explore these aspects within the Chinese population.Aim: The thesis aims to evaluate diet quality and adherence to the Chinese 2017 Dietary Guide for Chronic Kidney Disease Patients (WS/T 557-2017) in Chinese patients and to provide evidence on how adherence to recommendations from dietary guidelines influences the onset and progression of CKD.Study I is a cross-sectional study to investigates the dietary quality and adherence to Chinese CKD-specific nutritional guidelines among 261 non- dialysis-dependent CKD (NDD-CKD) stages G3-G5 patients. Findings revealed that a significant number of patients exhibited poor adherence to dietary recommendations, particularly regarding protein, energy, fiber, and sodium intake. The overall dietary quality in these patients was moderate, though characterized by notably reduced consumption of whole grains, dairy products, and soybeans.Study II evaluates the association between plant protein ratio and CKD progression in 259 CKD G3-5 patients. After a median follow-up period of 2.3 years, our analysis identified a U-shaped relationship between plant protein ratio and CKD progression, with a turning point observed at 47%. Among patients with a plant protein ratio below 47%, each 5% increase in the ratio was associated with a 33% reduction in the risk of disease progression.Study III included 197 participants with CKD stages 3-4 to evaluate the association between adherence to three healthy dietary indices and CKD progression and kidney function decline. Our key findings demonstrate that higher adherence to the Chinese Healthy Eating Index (CHEI) was associated with reduced CKD progression. Greater adherence to the CHEI and the healthy Plant-based Dietary Index (hPDI) was linked to a slower annual decline in eGFR in a dose-response manner. The Diet Quality Index-International (DQI-I) was not significantly associated with CKD progression or decline in eGFR.Study IV was a systematic review and meta-analysis. Evidence from four cohorts comprising 219,132 participants was synthesized to examine the association between ultra-processed food (UPF) consumption and the risk of developing CKD. The results indicated that higher UPF intake was associated with an increased risk of incident CKD.Conclusion: Patients with CKD stages 3-5 in our clinic exhibit that some nutrients that deviates from national recommendations and moderate diet quality. A U-shape association between plant protein ratio and CKD progression was observed in patients with CKD stages 3-5, with an inflection point at 47%. Among patients with CKD stages 3-4, greater adherence to the Chinese Healthy Eating Index (CHEI) was associated with a lower risk of CKD progression and a slower decline in kidney function. In the general population, higher consumption of UPFs was linked to an increased risk of developing CKD.List of scientific papersI. Ouyang W, Xiao B, Chen H, Fu L, Tang F, Marrone G, Liu X, Wu Y and Carrero JJ. Dietary quality and adherence to dietary recommendations in Chinese patients with chronic kidney disease. Front Nutr. 2025;12:1547181. https://doi.org/10.3389/fnut.2025.1547181II. Ouyang W, Chen H, Fu L, Tang F, Carrero JJ, Marrone G, Stålsby Lundborg C, Eriksen J, Liu X and Wu Y. U-shape Association Between Dietary Plant Protein Ratio and Chronic Kidney Disease Progression. [Manuscript]III. Ouyang W, Fu L, Tang F, Marrone G, Chen H, Wen Z, Wu Y and Liu X. Adherence to Four Dietary Indices and Chronic Kidney Disease Progression and Kidney Function Decline: Findings from the SMP-CKD Study. [Manuscript]IV. Xiao B, Huang J, Chen L, Lin Y, Luo J, Chen H, FU L, Tang F, Ouyang W, Wu Y. Ultra-processed food consumption and the risk of incident chronic kidney disease: a systematic review and meta-analysis of cohort studies. Ren Fail. 2024;46(1):2306224. https://doi.org/10.1080/0886022X.2024.2306224</p
Author Correction: A machine learning model predicts stroke associated with blood cadmium level
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