5,928 research outputs found
I Remember column in which author Eva LaPlante writes of her visits to sites a
No full textI Remember column in which author Eva LaPlante writes of her visits to sites associated with E. B. White and his book Charlotte\u27s Web
Eva Murray, author of Well Out to Sea , has been a resident of Matinicus Island
No full textEva Murray, author of Well Out to Sea , has been a resident of Matinicus Island since she moved there to teach at the island\u27s one-room schoolhouse in 1987. She discusses the differences between writing from an island and writing about an island as well as her efforts to dispel some stereotypes and myths about Matinicus through her writing
Generation of functional macrophages from adult mesenchymal stem cells
Full text linkvon Eva Freisinge
Different Behavior of the Histidine Residue toward Cadmium and Zinc in a Cadmium-Specific Metallothionein from an Aquatic Fungus
Full text linkMetallothioneins (MTs) are a large superfamily of ubiquitous cysteine-rich metalloproteins with main functions in metal ion homeostasis and detoxification. Neclu_MT1 is a metallothionein from the aquatic fungus Heliscus lugdunensis and so far the only known MT that is solely induced by CdII but not by ZnII or copper ions. In addition to eight cysteine residues, Neclu_MT1 also contains a less common single C-terminal histidine residue. To better understand the role of this histidine residue in metal ion binding, for the first time, potentiometric pH titrations are applied, revealing insights into the protonation and metal ion binding processes. Additional studies with absorption and NMR spectroscopy complement the finding that while the histidine residue is not crucial for the overall metal binding capacity, it does serve as a ligand in the ZnII but not in the CdII form of the protein
Obesity of Older School Age Children Based on Physical Activity and Eating Habits
Full text linkTITLE: Obesity of Older School Age Children Based on Physical Activity and Eating Habits AUTHOR: Bc. Eva Lamačová DEPARTMENT: Department of Education SUPERVISOR: PaedDr. Eva Marádová, CSc. ABSTRACT: This thesis deals with the obesity of older school age children and their dependence on eating and exercising habits. The theoretical part summarizes knowledge regarding overweight and obesity, disease diagnosis, epidemiological trends and complications related to obesity. Emphasis is put on the evaluation of reasons to why this problem occurs, such as disease prevention, dietary and exercise recommendations, its therapy and inclusion of the issue with the secondary school curriculum. The practical part contains research focused on the nutritional status, eating and exercise habits of pupils in secondary school. The survey results are designed for use in pedagogical practice. Usage is targeted for obesity prevention in this age group during Physical Education and Health Education subjects. KEYWORDS: Obesity, overweight, eating habits, exercising habit
ANALISIS PENDEKATAN ECONOMIC VALUE ADDED (EVA) TERHADAP KINERJA KEUANGAN PADA PERUSAHAAN MAKANAN DAN MINUMAN DI BURSA EFEK INDONESIA
Full text linkEconomic Value Added (EVA is one approach to measuring the financial performance of a company by focusing on the creation of value-added enterprises. EVA shows how big the resulting rate of return on the investment made by shareholders. In this paper, the object used by the author is wrong a company engaged in the food and beverage industry in Indonesia Stock Exchange. data used is the consolidated financial statements of the company in 2011-2012. purpose of this paper is to measure the financial performance of the EVA approach to food and beverage companies 2011-2012. Results analysis of the EVA calculation shows that by using the EVA approach, the financial performance of food and beverage companies can experience a volatile period 2011-2012. In 2011 the company's financial performance has improved food and beverage d in the presence of EVA is positive that the company has succeeded in achieving its goal create value-added enterprises. But in 2012 the company's food and beverage show poor financial performance since EVA generated negative worth. This means that in 2012, the company has not been able to create value for the rate of return expected by shareholders or the investment made. Keywords: Economic Value Added (EVA
Eva Urban. 'Lessing’s Nathan the Wise: from the Enlightenment to the Berliner Ensemble.'
No full textLessing's Nathan the Wise (1779), exemplary for its enlightenment and humanist ideals, assembles Jews, Christians, and Muslims in dialogue during the medieval crusades in Jerusalem. Their encounters allow them to transcend conflict, to recognize their common humanity, and to resolve their differences through dialectical discourse and group arguments. In this article Eva Urban looks closely at the representation of enlightenment in this play and examines the potential role of plays and theatre practice in developing autonomous citizenship and intercultural understanding. Particular reference is made to the 2013 Berliner Ensemble production of Nathan the Wise in relation to aesthetic debates about modern political drama. Eva Urban is a British Academy Postdoctoral Research Fellow at the Faculty of English, University of Cambridge, and an Associate of Clare Hall, Cambridge. She is the author of Community Politics and the Peace Process in Contemporary Northern Irish Drama (Peter Lang, 2010) and has published a number of articles on political drama and Irish studies
Metallo-drugs: development and action of anticancer agents/ edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel.
No full textIn English.Includes bibliographical references and index.Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.About the editors -- Historical development and perspectives of the series / Preface to volume 18 / Contributors to volume 18. -- 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. Subject index. Astrid Sigel, Helmut Sigel, Roland K.O. Sigel -- Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel -- Imogen A. Riddell, Stephen J. Lippard -- Viktor Brabec, Jana Kasparkova, Vijay Menon, Nicholas P. Farrell -- V. Venkatesh, Peter J. Sadler -- Nicholas P. Farrell, Anil K. Gorle, Erica J. Peterson, Susan J. Berners-Price -- Enzo Alessio, Luigi Messori -- Maria V. Babak, Wee Han Ang -- Angela Casini, Raymond Wai-Yin Sun, Ingo Ott -- Edit Y. Tshuva, Maya Miller -- Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang -- Christopher R. Chitambar -- Lucia Cardo, Michael J. Lucia -- Ramon Vilar -- Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger -- Ulrich Schatzschneider -- Frank Thévenod -- Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater -- Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor -- Cisplatin and oxaliplatin : our current understanding of their actions / Polynuclear platinum complexes : structural diversity and DNA binding / Platinum(IV) prodrugs / Metalloglycomics / The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Medicinal chemistry of gold anticancer metallodrugs / Coordination complexes of titanium(IV) for anticancer therapy / Health benefits of vanadium and its potential as an anticancer agent / Gallium complexes as anticancer drugs / Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Nucleic acid quadruplexes and metallo-drugs / Antitumor metallodrugs that target proteins / Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Iron and its role in cancer defense : a double-edged sword / Copper complexes in cancer therapy / Targeting zinc(II) signalling to prevent cancer /1 online resource (588 pages
Analisis Kinerja Keuangan Berdasarkan Metode economic value added (EVA) Pada PT. Surya Citra Media. Tbk
Full text linkThis study aims to measure and find out financial performance at PT. Surya Citra Media, Tbk using the method of Economic Value Added (EVA) for the period 2016 - 2020. This study uses this research using descriptive analysis method which aims to provide an overview of the actual financial performance of the company, where data collected, compiled, then analyzed and explained with existing theories and finally make conclusions and suggestions. Descriptive analysis method used in this study to describe in general PT. Surya Citra Media, Tbk, by describing the results of the analysis conducted in this study. The design of this study is to use a qualitative approach, where with this approach the author seeks to understand the analysis of financial performance using EVA methods.
The conclusion of this study shows that the financial performance of PT. Surya Citra Media, Tbk based on the analysis of Economic Value Added (EVA) from 2016 to 2020 is not good, where the value of EVA <0, ie for five consecutive years the company EVA shows a negative value. In 2016 the value of EVA - Rp. 788,228,366 and in 2017 the value of EVA again decreased significantly by -Rp. 2,101,912,330 and in 2018 amounting to Rp. 1,237,933,617 and decreased in 2019 to a figure of -Rp. 1,148,156,021 and in 2020 it fell to -Rp. 749,755,182. It is recommended for companies to increase EVA each year to reach a positive value by reducing or reducing the cost of capital while negotiating interest rates.
 
Definition, Epidemiologie und spezielle Pathophysiologie der der unteren Extremitäten
No full textDie akute Extremitätenischämie (ALI) ist eine Reduktion der arteriellen Perfusion mit potenzieller Bedrohung der Extremität und einer Symptomdauer von bis zu 14 Tagen. Die akute Extremitätenischämie (ALI) ist ein vaskulärer Notfall. Die Mortalitäts (10 %)- und Amputationsraten (6–8 %) während des stationären Aufenthaltes sind hoch. Die häufigsten Ursachen sind kardial embolisch oder ein lokal thrombotischer Verschluss (in-situ Thrombose). Die Differenzierung der dilatativ-aneurysmatischen Gefässkrankheit als Ursache der akuten Extremitätenischämie (ALI) ist wichtig, da sich die Therapie unterscheidet. Eine primär lebensbedrohliche Sonderform ist der akute Verschluss der Aorta abdominalis (Leriche Syndrom). Pathophysiologisch sind das Ausmass der Hypoxämie und die Dauer für die Entstehung von Gewebeuntergang prognostisch entscheidend. Der Grad der Gewebeschädigung hängt von der Reichweite des Kollateralzirkulation ab. Systemisch können komplizierend eine Rhabdomyolyse, akutes Nierenversagen sowie ein konsekutives Lungenödem hinzukommen
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