1,721,793 research outputs found
[Amnesty Letter ID092] / [Freeman, Michael B.
No full textThis letter was written by Michael B. Freeman to President Andrew Johnson in response to the President's Amnesty Proclamation of 29 May 1865. The writer indicates his county of residence as Rutherford Co. (North Carolina) and states his occupation as Farmer
A study of road transport development during the Industrial Revolution : Southern Hampshire, 1750-1850
No full textThe road transport developments in Britain during the period 1750-1850 have long been recognised as a vital element in the Industrial Revolution, yet, paradoxically, there have been few scholarly and detailed examinations of the nature and significance of these developments. A wide variety of sources is drawn upon - Parliamentary records, turnpike trust documentation, newspapers and directories, principal among them, while considerable use is made of graph theory as an aid to describing and analysing the region's developing transport system. Road transport in Southern Hampshire during the earlier eighteenth century was at a point of crisis: roads were in a poor condition, the mechanisms for maintaining them were ineffective and inadequate, and as a result, traffic expansion was much impeded. The solu- tion came with the widespread adoption of the turnpike concept from 1750. By the 1770s, a comprehensive and well-integrated system of turnpike roads was in existence and development continued up to 1841. Under the auspices of the region's turnpike trusts, far greater funds were devoted to road maintenance than ever before, and concerted efforts were made to stream- line the road system through widening, construction of 'cut-offs' and lowering of hills. The significance of these various changes is clearly reflected in the remarkable growth of traffic during the period, especially in the public transport sector. The traffic expansion was accompanied by a considerable improvement in rates of travel, often at no great advance in costs in relative terms. Viewed as a whole, such transport developments formed a highly important permissive, and at times positive, force in the movement towards greater regional urbanisation, in regional agricultural expansion and improvement, and in the decline of traditional industries and crafts. Preliminary comparison with the Yorkshire West Riding suggests that the experience of Southern Hampshire was more than repeated in the developing industrial regions.</p
Conformational rearrangements enable iterative backbone -methylation in RiPP biosynthesis
No full textR Code:
Supplementary Data 1. Code for running kinetics simulations
File name: Supplementary Data 1.R
Mass Spectrometry .raw files:
Supplementary Figure 4a-c. Mass spectrometric analysis of split borosin coexpressions.
File name: 20200110_FSM1167_SonA+SonM_24.5min.raw
Supplementary Figure 4d-j. Mass spectrometric analysis of split borosin coexpressions.
File name: 20200909_KC1063_StrA+StrM_15min_redalk_18pm4.raw
Supplementary Figure 16. SonM in vitro reactions analyzed by LC-MS/MS and
compared to kinetic model simulations.
File names:
20200220_FSM1178_kineticmodeling_t=2.raw
20200220_FSM1179_kineticmodeling_t=2.raw
20200220_FSM1180_kineticmodeling_t=8.raw
20200220_FSM1181_kineticmodeling_t=8.raw
20200220_FSM1182_kineticmodeling_t=20.raw
20200220_FSM1183_kineticmodeling_t=20.raw
20200220_FSM1184_kineticmodeling_t=40.raw
20200220_FSM1185_kineticmodeling_t=40.raw
20200220_FSM1186_kineticmodeling_t=60.raw
20200220_FSM1187_kineticmodeling_t=60.raw
Supplementary Figure 25a. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190701_kc1007_His-SonA_Y93F.raw
Supplementary Figure 25b. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190515_fsm1155_his-SonA-sonMT-R67K.raw
Supplementary Figure 25c. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190515_fsm1154_his-sonA_sonMTR67A.raw
Supplementary Figure 25d. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190701_kc1008_His-SonA_Y58F.raw
Supplementary Figure 25e. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190515_fsm1156_his-sonA-SonMT-Y71F.raw
Supplementary Figure 25f. Mass spectrometric analysis of SonM mutant in vitro
reactions.
File name: 20190701_kc1009_His-SonA_DBLMUT.rawThe data deposited here are raw files, R code and mass spec, associated with the results presented in the paper, "Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis." These data have been made publicly available in keeping with the journal's data availability policy.National Institutes of Health (R35 GM133475 to M.F.F.) and the University of Minnesota along with the BioTechnology Institute (M.F.F., M.H.E., W.A.H.)Miller, Fredarla S.; Crone, Kathryn K.; Jensen, Matthew R.; Shaw, Sudipta; Harcombe, William R.; Elias, Mikael H.; Freeman, Michael F.. (2021). Conformational rearrangements enable iterative backbone -methylation in RiPP biosynthesis. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/y8ry-gm18
Traffic Injury Investigation
No full textCausal analysis in traffic crash–related injury and death investigation is a common application of epidemiologic concepts and data. In combination with medical, biomechanical, and crash reconstruction principles, forensic epidemiology (FE) methods are used to quantify the efficacy of vehicle safety devices such as seat belts and air bags. This application of FE is demonstrated with several case study examples in this chapter. Additional case studies illustrate how FE methods are used to evaluate the probability of causation of injuries observed following lower speed collisions. The final case study illustrates an analysis of the most probable cause of a death following two high speed collisions, occurring within seconds of each other. Other examples in the chapter are used to demonstrate fallacious pitfalls commonly observed in causal evaluations of crash-related injury
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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