1,721,030 research outputs found

    Ultrasonography diagnosis

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    Fetal growth is a dynamic process determined by a combination of genetic, intrauterine, and environmental influences. However, assessment of fetal growth with a onetime measurement is standard clinical practice, despite recognition that a single measurement can only indicate size, not growth. For this purpose, the fetal biometric measurements commonly used are biparietal diameter, head circumference, abdominal circumference, and femur length. These measurements can be combined into an estimated fetal weight using various formulae to provide a more straightforward and clinically relevant estimate of fetal growth. There are many published fetal growth charts available, and the choice of chart used also requires careful consideration as several potentially confusing terms and concepts associated with fetal size and growth are reported in the literature: fetal growth “standards,” fetal growth “references,” customized charts, and growth velocity standards. The relative merits and disadvantages of each approach are discussed, although none has so far proved to be clearly superior to the others. As for the timing of third trimester ultrasound screening for term fetal growth restriction, which is not currently recommended in most countries, recent studies of high methodological quality suggest that ultrasound assessment at 35–37 weeks performs better than at 30–32 weeks

    Twin reversed arterial perfusion sequence: current treatment options

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    Twin reversed arterial perfusion (TRAP) sequence is a specific and severe complication of monochorionic multiple pregnancy, characterized by vascular anastomosis and partial or complete lack of cardiac development in one twin. Despite its rarity, interest in the international literature is rising, and we aimed to review its pathogenesis, prenatal diagnostic features and treatment options. Due to the parasitic hemodynamic dependence of the acardiac twin on the pump twin, the management of these pregnancies aims to maximize the pump twin’s chances of survival. If treatment is needed, the best timing of intervention is still debated, although the latest studies encourage intervention in the first trimester of pregnancy. As for the technique of choice to interrupt the vascular supply to the acardiac twin, ultrasound-guided laser coagulation and radiofrequency ablation of the intrafetal vessels are usually the preferred approaches

    Transabdominal uterine artery Doppler between 11 and 14 weeks of gestation for the prediction of outcome in high-risk pregnancies

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    Objective. To assess the value of early transabdominal uterine artery Doppler ultrasound for the prediction of gestational outcomes in pregnancies at high risk for preeclampsia. Methods. This was an observational study. Doppler ultrasound of the uterine arteries at 11-14 weeks of gestation was performed in 76 women at high risk for preeclampsia. Abnormal uterine Doppler was defined by the presence of bilateral notching or by a mean resistance index (RI) >0.80. Adverse outcomes evaluated were preeclampsia, fetal growth restriction, placental abruption, intrauterine death, and complications requiring delivery before 34 weeks of gestation. Results. Among 76 women, 30 (39%) had abnormal uterine Doppler and 46 (61%) had normal Doppler waveform configuration and RI. Abnormal uterine flow was related to a significantly higher incidence of preeclampsia (17% vs. 0%; p = 0.0041), fetal growth restriction (27% vs. 0%; p = 0.0002), intrauterine death (13% vs. 0%; p = 0.0109), and iatrogenic preterm delivery (20% vs. 2%; p = 0.0086). When the Doppler was normal, the negative predictive value for complications requiring delivery before 34 weeks was 98%. Conclusions. Normal impedance to flow in uterine arteries between 11 and 14 weeks of gestation is strongly related to a normal pregnancy outcome in women at high risk for preeclampsia. © 2008 Informa UK Ltd
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