1,673 research outputs found
Practical Equality: Discussion with Author Robert L. Tsai
No full textProfessor Timothy Zick discusses a new book titled Practical Equality: Forging Justice in a Divided Nation, with its author, Professor Robert L. Tsai of American University Washington College of Law. Timothy Zick is the John Marshall Professor of Government and Citizenship at William & Mary Law School. His scholarship has explored a wide variety of constitutional issues, with a special focus on the First Amendment. Robert L. Tsai is Professor of Law at American University and a prize-winning essayist in constitutional law and history. Recorded before a live audience at William & Mary Law School on March 14, 2019. The event was sponsored by the American Constitution Society. Professor Tsai was also a panelist during the annual Bill of Rights Journal Symposium on March 15 & 16, 2019
Exploiting Domain Knowledge in Making Delegation Decisions
No full text@inproceedings{conf/admi/EmeleNSP11, added-at = {2011-12-19T00:00:00.000+0100}, author = {Emele, Chukwuemeka David and Norman, Timothy J. and Sensoy, Murat and Parsons, Simon}, biburl = {http://www.bibsonomy.org/bibtex/20a08b683088443f1fd36d6ef28bf6615/dblp}, booktitle = {ADMI}, crossref = {conf/admi/2011}, editor = {Cao, Longbing and Bazzan, Ana L. C. and Symeonidis, Andreas L. and Gorodetsky, Vladimir and Weiss, Gerhard and Yu, Philip S.}, ee = {http://dx.doi.org/10.1007/978-3-642-27609-5_9}, interhash = {1d7e7f8554e8bdb3d43c32e02aeabcec}, intrahash = {0a08b683088443f1fd36d6ef28bf6615}, isbn = {978-3-642-27608-8}, keywords = {dblp}, pages = {117-131}, publisher = {Springer}, series = {Lecture Notes in Computer Science}, timestamp = {2011-12-19T00:00:00.000+0100}, title = {Exploiting Domain Knowledge in Making Delegation Decisions.}, url = {http://dblp.uni-trier.de/db/conf/admi/admi2011.html#EmeleNSP11}, volume = 7103, year = 2011
Marker-Based Paternity Test in Polycross Breeding of Timothy
No full textAlthough the polycross is a useful and cost effective mating design, a lack of paternal pedigree information is a major limitation for polycross breeding in forage grasses such as timothy (Phleum pratense L.). This study describes a paternity test for use in timothy breeding using polymorphic data on 27 genomic simple sequence repeat markers. The paternity test is a simple exclusion statistical test with a combination of maternal information. It successfully determined paternity (success rate = 97%) for 112 progeny plants derived from three polycross groups (A, B, and D). Indirectly selected paternal parents in polycrosses were inferior to maternal parents directly selected by polycross progeny tests mainly for forage yield. Chi-squared values (χ2) in goodness-of-fit tests of the frequency distribution of paternal parents compared with the expected probabilities revealed unbalanced selection in Polycrosses B and D (χ2 = 141.4*** and 82.7***, respectively). Significant differences among the maternal and paternal parents in breeding values for competitiveness toward legumes and low-digestibility fiber content indicate that unbalanced paternal selection would result from individual phenotypic selection for these traits. These results demonstrate that implementation of a marker-based paternity test in timothy polycross breeding could significantly improve the selection of superior paternal parents and redress problems of parental imbalance
Evaluating Research Impact through Open Access to Scholarly Communication
No full textScientific research is a competitive business – in order to secure funding, promotion and tenure researchers must demonstrate their work has impact in their field. To maximise impact researchers undertake high priority research, aim to get results first, and publish in the highest impact journals. The Internet now presents a new opportunity to the scholarly author seeking higher impact: s/he can now make their work instantly accessible on the Web through author self-archiving. This growing body of open access literature (coupled with new publishing models that make journals available for-free to the reader) maximises research impact by maximising the number of people who can read it, and making it available sooner. Open access also provides a new opportunity for bibliometric research. This thesis describes the relatively recent phenomenon of open access to research literature, tools that were built to collect and analyse that literature, and the results of analyses of the effect of open access and its effect on author behaviour. It shows that articles self-archived by authors receive between 50-250% more citations, that rapid pre-printing on the Web has dramatically reduced the peak citation rate from over a year to virtually instant and how citation-impact – now widely used for evaluation – can be expanded to include a new web metric of download impact
Clarinet quintet in A major, K. 581 ; Horn quintet in E-flat major, K. 407 ; Divertimento in D major, K. 251
No full textMore Author/Title Info: Mozart, Wolfgang Amadeus
Physical Description: 1 audio disc : digital ; 4 3/4 in.
Performers: Stanley Drucker, clarinet (1st work) ; Joseph Robinson, oboe (3rd work) ; L. William Kuyper (2nd & 3rd works), R. Allen Spanjer (3rd work), horns ; Timothy Cobb, double bass (3rd work) ; Elysium String quartet (Jennifer Tiboris, Gary Levinson, violins ; Veronica R. Salas, viola ; Lutz Rath, violoncello).
Event Details: Recorded at the American Academy of Arts and Letters, New York City, Sept. 21, Dec. 2 and 6, 1998
Roma, magistra mundi. Itineraria culturae medievalis. Mélanges offerts au Père L.E. Boyle à l\u27occasion de son 75e anniversaire
No full textR. James Long (with Timothy B. Noone) is a contributing author, Fishacre and Rufus on the Metaphysics of Light: Two Unedited Texts , Volume 2, pp. 517-548
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
Use of molecular marker diversity to increase forage yield in timothy (Phleum pratenseL.)
No full textMolecular marker technologies may provide a tool to overcome the forage yield plateau in timothy (Phleum pratense L.). Therefore, a study was designed to investigate the relationship between marker-based genetic distance (GD) estimates and yield. Genetic distances were estimated using Dice coefficients framed by 28 simple sequence repeat markers. In Experiment 1, parents with high general combining ability (GCA) from two contrasting first-generation synthetic strains (exhibiting high and low yields) were compared. Average GDs of each strain were 0.74 (high) and 0.68 (low). These differences indicated that GD may be partially the basis for contrasting yields. In Experiment 2, GDs among 40 parents of a polycross were used for calculating general genetic distance (GGD), which is indicative of their allelic complementation. Analyses revealed a significant (P < 0.01) moderate correlation (r) between GGD and GCA for yield (r = 0.45) and a significant (P < 0.01) residual mean square for the regression of yield on GGD, suggesting that considerable non-additive effects were associated with GCA. The results are indicative of the potential use of GD estimation for yield improvement in timothy
A Note on Isomorphisms Between Canonical Frames
No full textThis paper looks at the question of what kinds of automorphisms and isomorphisms can exist within and between canonical frames for modal logics. Specifically, this paper is able to partially answer the question posed by the author in [7] of whether F L ! ¸ = F L !1 in the presence of the extra-ZFC axiom "2 ! = 2 !1 ." We answer the question in the negative for all logics below S5 and for all logics satisfying a natural condition. In addition we look at automorphisms and show that while canonical frames for S5 in particular, and logics of bounded alternative in general, have many non-standard automorphisms, the logics satisfying the aforementioned natural condition have none. A Note on Isomorphisms Between Canonical Frames Timothy J. Surendonk January 1, 1997 Abstract This paper looks at the question of what kinds of automorphisms and isomorphisms can exist within and between canonical frames for modal logics. Specifically, this paper is able to partially answer the question ..
Increasing Distributed Generation Penetration using Soft Normally-Open Points
No full textThis paper considers the effects of various voltage control solutions on facilitating an increase in allowable levels of distributed generation installation before voltage violations occur. In particular, the voltage control solution that is focused on is the implementation of `soft' normally-open points (SNOPs), a term which refers to power electronic devices installed in place of a normally-open point in a medium-voltage distribution network which allows for control of real and reactive power flows between each end point of its installation sites. While other benefits of SNOP installation are discussed, the intent of this paper is to determine whether SNOPs are a viable alternative to other voltage control strategies for this particular application. As such, the SNOPs ability to affect the voltage profile along feeders within a distribution system is focused on with other voltage control options used for comparative purposes. Results from studies on multiple network models with varying topologies are presented and a case study which considers economic benefits of increasing feasible DG penetration is also given
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