1,720,963 research outputs found
Instrumental and clinical assessment of the efficacy and tolerability of a topical product with benzoyl peroxide combined with a detergent for acneic skin
No full textBackground. Benzoyl peroxide (BP) has been widely used in the therapy of acne for its antimicrobial and keratolytic properties. Data on its efficacy and observations on its irritant effects have been reported in the literature. Moreover, the use of detergents which are often associated in the treatment of acne, promotes in some cases the appearance of irritant phenomena. The aim of this study was to evaluate the efficacy and tolerability of a topical product containing benzoyl peroxide (BP), used in combination with a detergent for acneic skin, by means of clinical evaluation and instrumental methods assessing biophysical parameters. Methods. Thirty volunteers with polymorphic acne of the face were enrolled in the study. Fifteen of them used a topical gel with BP and a detergent, whereas the other 15 applied only the BP preparation for 45 days. In both groups the cutaneous biophysical parameters of hydration, pH and sebum level were investigated at three different areas (forehead, cheek and mediofacial zone). Moreover, the number and type of lesions at a selected skin area were counted and described, and the objective and subjective tolerability were assessed. Evaluations were carried out before treatment and after 20 and 45 days. Results. The total number of the acneic lesions appeared significantly decreased in all subjects, especially in those who had used the BP preparation and the detergent in combination. In both groups we observed an increase in hydration and a decrease in pH after 20 and 45 days of treatment, whereas sebum levels were unaffected. Conclusion. The results obtained confirm that BP is a valid molecule for the treatment of acne. Its use in combination with a detergent enhances its action. Moreover, no alterations of pH, hydration and sebum levels are induced by its use, and this underlines its good tolerability
Efficacy of two lenitive and restorative topical products: Assessment of biophysical skin perameters
No full textBackground. The aim of this study was to evaluate visually and by means of non invasive measuring techniques the efficacy of two topical products, a spray and a gel, considered as lenitive and restorative after plastic surgery. Methods. Twelve healthy subjects entered the study. For each subject 3 test sites on the left volar forearm (areas 1, 2, 3) were treated for 30′ with 40 μl of 70% glycolic acid solution, whereas 3 test sites on the right (areas 4, 5, 6) were treated with 5% of SLS solution for 30′. Immediately after removal and after each assessment, 20 mg of gel and 40 ml of spray were applied on sites 2 and 5 and on sites 3 and 6, respectively. Clinical and instrumental evaluation (TEWL, capacitance, colorimetry and echography) were performed prior to the first application and at different times. Results. Visual scoring and colorimetry didn't show significant variations respect to baseline. TEWL assessment showed a rapid and persistent increase which was less evident on the areas treated with glycolic acid and gel. This product could also significantly contrast the capacitance decrease caused by SLS. Ultrasonographic evaluation showed superficial hypoechogenicity and edema. Gel and spray applications induced slighter variations with respect to baseline in the extension of hyperreflecting dermal areas. Conclusions. In conclusion, these products showed a fairly good protective and barrier restoring action together with a slight antiedematous effect
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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