2,969 research outputs found
Fundamentals of Material Design Culture
No full textThis essay is published in the book Ideas and the Matter, edited by Marinella Ferrara and Giulio Ceppi. The book presents the founding research undertaken by the Politecnico di Milano’s Material Design Culture Research Centre (Madec). Founded in 2014, Madec obtained the Design Department’s support during its first year by being granted the Fondo di Ateneo per la Ricerca di Base (FARB 2013) for “Fundamental/Foundational/ Exploratory Researches that are strategically assessed for scientific growth in a research department”. In the third section of the book, scientific discourse focuses on the Material Design Culture and changing approach in term of the evolution of research methods. In the chapter "Fundamental of Material Design Culture", the author traces the fundamentals of Material Design based on the Italian design history and its relationship with global design discourse
Shifting to Design-driven Material Innovation
No full textThis essay is published in the book Ideas and the Matter, edited by Marinella Ferrara and Giulio Ceppi. The book presents the founding research undertaken by the Politecnico di Milano’s Material Design Culture Research Centre (Madec). Founded in 2014, Madec obtained the Design Department’s support during its first year by being granted the Fondo di Ateneo per la Ricerca di Base (FARB 2013) for “Fundamental/Foundational/ Exploratory Researches that are strategically assessed for scientific growth in a research department”. In the third section of the book, scientific discourse focuses on the Material Design Culture and changing approach in term of the evolution of research methods. In this chapter, the author analyses several changes in the design discipline and in the approaches to Material design and explores the new dimension of the contemporary trend of material innovation driven by design competences
El básquetbol como una estructura co-variante
No full textEsta presentación tiene como propósito presentar y compartir un conjunto de ideas que ayuden a pensar el básquetbol como una estructura co-variante. Por otra parte, trabaja los conceptos de dualidad destreza-habilidad dentro de las prácticas corporales en general y en el básquetbol en particular.Fil: Ferrara, Francisco. I.S.F.D N° 84
El básquetbol como una estructura co-variante
No full textEsta presentación tiene como propósito presentar y compartir un conjunto de ideas que ayuden a pensar el básquetbol como una estructura co-variante. Por otra parte, trabaja los conceptos de dualidad destreza-habilidad dentro de las prácticas corporales en general y en el básquetbol en particular.Fil: Ferrara, Francisco. I.S.F.D N° 84
El básquetbol como una estructura co-variante
No full textEsta presentación tiene como propósito presentar y compartir un conjunto de ideas que ayuden a pensar el básquetbol como una estructura co-variante. Por otra parte, trabaja los conceptos de dualidad destreza-habilidad dentro de las prácticas corporales en general y en el básquetbol en particular.Fil: Ferrara, Francisco. I.S.F.D N° 84
Ferrara città creativa
No full textIl saggio indaga il tema della creatività urbana a partire dall’illustrazione di tre pratiche locali sbocciate all’improvviso a Ferrara a partire dal 2012. Il recente fenomeno di creatività che si è manifestato a Ferrara viene messo in relazione con i risultati di trent’anni di politiche culturali e per il turismo promosse dalla città. In conclusione vengono sviluppate alcune considerazioni sia sulle pratiche illustrate, sia sulle condizioni generali per favorire questo tipo di sviluppiThe essay explores the theme of urban creativity from the illustration of three local practices suddenly blossomed in Ferrara from 2012. The recent phenomenon of creativity that is manifested in Ferrara is put in relation by the author with the results of thirty years of cultural and tourism policies promoted by the City. In conclusion, some considerations are developed both on the practices discussed, both on the general conditions to encourage this type of development
Amazonian plants from ethnomedicine to biotechnology through pharmaceutical biology approaches: a PhD experience in connecting forest with laboratory
No full textThe South american Natives, Shuar and Achuar people and their ethnomedical culture constitute the
background subject of the Phd research, performed both in Ecuador (Salesian Politechnic University,
Quito), and in Italy (Pharmaceutical biology labs, University of Ferrara). Based on ethnomedical
responses, Piper aduncum, Maytenus macrocarpa, Schinus molle, Tecoma stans and Eugenia hallii were
chosen as amazonian plant species subject of the research.
AIMS
The research has been focused on:
− checking the presence of endophytic fungi in plants;
− isolating and subculturing pure endophytic strains;
− checking the biotransformation capacity of the isolated endophytes on pure compounds; the most
performing endophytes were also tested on phytocomplexes and pure chemicals obtained by the
plant from which the fungi were isolated;
− phytochemical characterization and bioactivity assays of plant extracts: P. aduncum.
−
METHODS
Biotransformations. Fresh aerial plant parts were properly washed in sanitizing solutions and in vitro
cultured using adequate solid media to isolate endophytes. (+/-)-cis-bicyclo[3.2.0]hept-2-en-6-one,
acetophenone, 1-indanone, 2-furyl methyl ketone, 2-methylcyclopentanone, 2-methylcyclohexanone, 2-
methoxycyclohexanone were chosen as substrate model for biotransformations. The cultures were
sampled after 1, 3, 7, 10 days of culturing, and ethyl acetate extracted to verify by GC-MS the presence of
possible biotransformation products. Biotransformations were also checked on P. aduncum whole
essential oil and on dillapiol, cis-ocimene, piperitone, (-)-terpinen-4-ol as most abundant chemicals.
Chemical fingerprinting of P. aduncum essential oil. Steam distillation was adopted to obtain the essential
oil, then characterized by GC-MS, NMR analyses.
In vitro bioassays of P. aduncum essential oil. Antimicrobial activities were checked in vitro using proper
agarized media to reach MIC. Antioxidant capacities were checked through DPPH test, ABTS and
photochemiluminescence assays. Born's turbidimetric method and Writhing test were respectively
adopted to check platelet-aggregation and anti-nociceptive properties. Mutagenic, antimutagenic
properties and toxicity were assayed using classical and modified Ames test.
MAIN RESULTS
364 fungal strains were in vitro isolated. Among all, 5 strains performed biotransformations on
acetophenone to (S)-1-phenylethanol, with important yields (78-97%) and enantiomeric excess (78-
100%). Three strains gave also phenols probably by enzymatic reactions (Baeyer-Villiger oxidations). 15
fungal strains gave the lactones (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one and (-)-(1R,5S)-3-
oxabicyclo[3.3.0]oct-6-en-2-one from (+/-)-cis-bicyclo[3.2.0]hept-2-en-6-one, probably as result of
monooxygenase activation. Phytochemical characterization of P. aduncum essential oil has evidenced
dillapiol as the most abundant terpene, followed by cis-ocimene, piperitone and terpinen-4-ol. Only cisocimene
and piperitone gave several biotransformation products through dehydrogenation and
hydroxylation reactions. The essential oil has evidenced non-mutagenic properties and interesting
antifungal and antioxidant activities.
CONCLUSIONS
Several endophytic fungal strains from Amazonian plants were isolated and checked for
biotransformations on pure chemicals and on P. aduncum essential oil. Data obtained will be useful for
possible following patents about micro-organisms able to transform pharmaceutically interesting
chemicals. Taxonomical characterization of the most performing fungal strains is still in progress. P.
aduncum essential oil can be considered genotoxically safe and provides interesting antifungal and
antioxidant properties, supporting its ethnomedical use as cicatrising and disinfectant crude drug and
suggesting an extension of its employ as preservative ingredient
«Cronologia»
No full textIl contributo chiude il catalogo della mostra organizzata dalla Fondazione Ferrara Arte e dal Centre for Fine Arts di Bruxelles e dedicata al pittore spagnolo Francisco de Zurbarán (Ferrara, Palazzo dei Diamanti, 14 settembre 2013 – 6 gennaio 2014); traccia la biografia dell'artista, considerato il "Caravaggio spagnolo", fornendo inoltre informazioni storiche sul periodo in cui visse e operò
CARATTERIZZAZIONE ELETTRICA E SPETTROSCOPICA AD IMPEDENZA DI OSSIDI METALLICI NANOSTRUTTURATI PER IL RILEVAMENTO DI ALCANI VOLATILI
No full textChemoresistive gas sensors using semiconductor metal-oxides have proven to be excellent in important characteristics such as sensitivity, long-term stability, robustness and price. Solid solutions of mixed Sn and Ti oxides have shown promising results in combining the properties of the separate components. Basic science of these mixed oxides is far from being satisfactorily elucidated. Further progress in basic understanding is required to establish the principles to operate them as gas sensors.
Knowledge of the space charge width of the nanostructured powder grains is needed for the comparison of the mean grain radius to determine sensing properties of the nanostructure. A new method has been addressed using impedance spectroscopy technique to estimate the electric permittivity of these Sn and Ti oxides, which is fundamental for the determination of the space charge width and capacitive response.
A study of the sensing properties of chemoresistive metal-oxides vs. light alkanes has been undertaken under dry and wet conditions and even in presence of ethanol. Screen-printed films of pure Sn and Ti oxides and solid solutions of mixed Sn and Ti oxides have been selected for the purpose. It has been demonstrated that the films are capable of detecting 500ppm of methane or 100ppm of other light alkanes under either dry or wet condition, i.e. concentrations two levels by far lower than the alarm thresholds for such gases. Information about the working mechanism of chemical reactions on the surface has been discussed under either dry or wet condition. Ethanol is known to be a harmful interfering gas, though its concentration can be reduced to values lower than 10ppm by proper activated carbon filtering. It has been shown that, even in presence of 10ppm of ethanol, the films steadily responded to alkanes
Correction to: Curve of Spee modification in different vertical skeletal patterns after clear aligner therapy: a 3D set-up retrospective study (Progress in Orthodontics, (2024), 25, 1, (5), 10.1186/s40510-023-00503-1)
No full textCorrection to: Prog Orthod.25, 5 (2024) https://doi.org/10.1186/s40510-023-00503-1. Following publication of the original article [1], the authors identified an error in the author names of the author group as the given name and family name were erroneously transposed. The incorrect author names are: Ciavarella Domenico, Fanelli Carlotta, Suriano Carmela1, Campobasso Alessandra, Lorusso Mauro, Ferrara Donatella, Maci Marta, Esposito Rosa and Tepedino Michele The correct author names are: Domenico Ciavarella, Carlotta Fanelli, Carmela Suriano, Alessandra Campobasso, Mauro Lorusso, Donatella Ferrara, Marta Maci, Rosa Esposito and Michele Tepedino The author group has been updated above and the original article [1] has been corrected
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