188 research outputs found

    The determinants of football attendance: new evidence from Italy and future lines of research.

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    This paper investigates the determinants of football attendance on the basis of a unique data set of all fixtures of Italian “Serie A” from season 2004/2005 to season 2010/2011, including a comprehensive list of sport, economic and socio-demographic variables. The paper provides important insights to sport and city managers in order to enhance the demand for football. Results indicate that the degree of competition between teams and the quality of players are important factors of attraction. The introduction of anti-violence measures also affects attendance but differently for committed and uncommitted fans. Moreover, the increase in attendance brought by the World Cup victory in 2006 is more than offset by the decrease induced by the “Calciopoli” scandal

    Orthodontic problems of pathological frenulum: importance of intercepted diagnosis and of timing treatment

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    Background: The frenula of the oral cavity are anatomical structures, histologically constituted by a fibromucosa, which join the inner surface of the upper and lower lip with the buccal mucosa of the alveolar process (frenula labial median and lateral) and the ventral surface of the tongue with the floor of the mouth (lingual frenulum). The oral frenula normally undergo changes in shape, size and position during the different stages of growth and development of the people. When they arise changes in morphological and structural characteristics, leading to pathological conditions of various kinds and severity, such frenula defining pathological. Objectives: In this work, analysis is performed of the etiophatogenesis, diagnostic elements and timing of therapeutic treatments toward these clinical cases, further into detail orthodontics problems. Methods: The intervention of the odontologist with a thorough clinical examination radiographic investigations and assisted by an early framing of the patient, are the best diagnostic and therapeutic approach. Results: The problems arising from late or non-intervention in the case of pathological frenula, may lead to significant morphological and structural of the patient. Discussion and Conclusions: The complex clinical and issues related to abnormalities of frenula of the oral cavity, require an adequate knowledge of the development processes of the organism and diagnostic procedures, in order to preserve structural and functional integrity of stomatognathic system, structures and organs connected to it

    Bucket-handle meniscal tears in children under the age of 10: a literature review

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    Traumatic meniscal tears are raising in skeletally immature patients due to increasing participation in sport activities. Nonetheless, meniscal tears remain a rare injury in children, with a lack of evidence regarding treatment and outcome. The aim of the study is to review the literature on BHMT in children aged under 10 years

    Return to competition after an Achilles tendon rupture using both on and off the field load monitoring as guidance: A case report of a top-level soccer player

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    OBJECTIVES: To describe the Return to competition after Achilles Tendon rupture (ATR) in an elite soccer player. DESIGN: Case report. SETTING: Return to sport (RTS) of a professional soccer player who suffered an ATR during a match. The RTS phase started 15 weeks after surgery and specific on-field activities were gradually introduced. Criteria used to monitor the transition through the different phases were strength and endurance of the calf muscle and ability to sustain specific on-field training loads (TL) monitored with Global Positioning System and heart-rate system. TLs were weekly compared to pre-injury values to evaluate recovery and to prescribe future sessions. PARTICIPANT: A 39-year-old (height 178 cm, weight 75 kg) elite soccer defender player, playing in Italian Serie-A league. RESULTS: Days of absence were lower compared to a cohort presented in UEFA study (119 versus 161 ± 65 days, respectively). External-TL and Internal-TL were organized to gradually increase during RTS and resulted in higher values prior to return to competition compared to pre-injury values. Concentric plantar flexion peak torque increased till 9th months after surgery. CONCLUSIONS: Monitoring of the field activities allowed comparison with pre-injury values and provided a useful and functional criteria to pass return to team activity and competition

    Complete Remission of Advanced Hepatocellular Carcinoma Treated with Sorafenib and Concomitant Appearance of IgG4- related Diseases. A Case Report

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    Sorafenib is currently the gold standard therapy for palliative treatment of advanced hepatocellular carcinoma (HCC) in patients with compensated liver disease. There are few cases reported in literature describing patients with HCC achieving a complete remission (CR) due to Sorafenib therapy. We report the case of a 62-year old patient who obtained CR despite single, long drug discontinuation and kept it without any maintenance therapy. Furthermore, this is the first case describing the onset of a likely IgG4-related retroperitoneal fibrosis and cholangitis during Sorafenib administration. Further studies are required to define the predictors of a good response to Sorafenib and to codify a therapeutic maintenance regimen for patients who achieve C

    Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term Cultures

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    Human Mesenchymal Stem Cells (hMSCs) undergo senescence in lifespan. In most clinical trials, hMSCs experience long-term expansion ex vivo to increase cell number prior to transplantation, which unfortunately leads to cell senescence, hampering post-transplant outcomes.Hydrogen peroxide (H2O2) in vitro represents a rapid, time and cost-effective tool, commonly used as oxidative stress tantalizing the stem cell ability to cope with a hostile environment, recapitulating the onset and progression of cellular senescence.Here, H2O2 at different concentrations (ranging from 50 to 400 mu M) and time exposures (1 or 2 hours - h), was used for the first time to compare the behavior of human Adipose tissue-derived Stem Cells (hASCs) and human Wharton's Jelly-derived MSCs (hWJ-MSCs), as representative of adult and perinatal tissue-derived stem cells, respectively. We showed timely different responses of hASCs and hWJ-MSCs at low and high subculture passages, concerning the cell proliferation, the cell senescence-associated beta-Galactosidase activity, the capability of these cells to undergo passages, the morphological changes and the gene expression of tumor protein p53 (TP53, alias p53) and cyclin dependent kinase inhibitor IA (CDKN IA, alias p21) post H2O2 treatments.The comparison between the hASC and hWJ-MSC response to oxidative stress induced by H2O2 is a useful tool to assess the biological mechanisms at the basis of hMSC senescence, but it could also provide two models amenable to test in vitro putative anti-senescence modulators and develop anti-senescence strategies
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