738 research outputs found
L'Officiolo di Francesco da Barberino
No full textDescrizione codicologica e inquadramento storico-paleografico del ms. contenente l'Officiolo di Francesco da Barberino, testimone di grande importanza anche per gli studi danteschi
Atypical protein kinase C dysfunction and the metabolic syndrome.
No full textAtypical protein kinase C isoforms are crucial mediators of glucose uptake in insulin-sensitive tissues. In humans, decreased muscular atypical protein kinase C activity has been found in insulin-resistant states. In a recent report by Farese et al., a novel mouse model is described, featuring selective ablation of an atypical protein kinase C, protein kinase Clambda, in muscle. Phenotyping of these mice demonstrated systemic insulin resistance, reduced glucose tolerance, abdominal obesity and dyslipidemia, thus mimicking human metabolic syndrome. Intriguingly, therefore, atypical protein kinase Clambda deficiency might be sufficient to induce metabolic syndrome in mice
The role of protein kinase C isoforms in insulin action.
No full textInsulin action on target tissues is mediated by specific tyrosine kinase receptors. Upon ligand binding insulin receptors autophosphorylate and phosphorylate intracellular substrates on tyrosine residues. These early events of insulin action are followed by the activation of a number of enzymes, including protein kinase C (PKC). At least 14 PKC isoforms have been identified and cloned to date. PKCs appear to play dual roles in insulin signaling. For instance, they are involved in transduction of specific insulin signals but also contribute to the generation of insulin resistance. In this article, we will analyze the experimental evidence addressing the mechanism by which insulin might activate individual PKC isoforms as well as the role of single PKCs in insulin-induced bioeffects
The role of banks in the sustainable development of territory: an ecosystems view
No full textIn the last years, several issues, ranging from globalization to sustainable development, have increased the level of complexity in managing social and economic dynamics by underlying the need for a systems approach (Espejo, 1994; Barile, 2009; Golinelli, 2010; Espejo & Reyes, 2011; Olsson & Bosch, 2014). The progressive widening of the interconnectedness between phenomena makes apparent the complex nature of socioeconomic by highlighting their multi-dimensional dynamics (Akaka et al., 2012; Barile et al., 2015, 2016; Caputo, 2016).
In this context, the traditional view of territory as an objective area in which actors live has been surpassed by recognizing its irreducible systemic functioning (Barile et al., 2013b). This perspective has been progressively developed by researchers from different disciplinary domains leading to recognize the need for an ecosystems view in the study of social and economic dynamics (Akaka et al., 2013; Vargo et al., 2015).
A new vision of territory development in which actors are engaged in collaborative relationship to foster a sustainable development of territories is emerging (Cooke, & Lazzeretti, 2008). By embracing the ecosystems view, it becomes apparent that the territory development is an emerging outcome that requires the engagement of all the interested actors in a shared value co-creation logic (Barile & Saviano, 2013, 2014; Barile et al., 2013a; Lusch et al., 2016). Economic, social and environmental dynamics are intertwined in a complex adaptive systems functioning (Holland, 1992). Therefore, each actor need to harmonize his/her behaviour with social, economic, and environmental dynamics to contribute to trigger virtuous circles of development (Akaka & Vargo, 2015; Di Nauta et al., 2015; Saviano, 2016).
Among the key actors for territory development, banks are expected to play a relevant role (Formisano et al., 2016). Along the time, banks have progressively developed competitive logics based on a view of belonging to an autonomous economic sector in which to develop and maintain a competitive advantage (Hempel & Simonson, 1999). Although the banks’ willingness to pursue their survival is legitimate and correct, in many cases, the ways in which they have pursued this aim has weakened their traditional mission of serving and sustaining the development of territory (Rich, 2013) by contributing to trigger a vicious circle of stagnation (Palley, 2012). Conversely, as the ecosystems view highlights, banks are one of the numerous actors (from policy makers to the citizens themselves) that must be engaged to share the mission of territory development. Development must be economically, socially, and environmentally sustainable (Girard & Nijkamp, 2009; Denicoali et al., 2010; Hu & Scholtens, 2014; Golinelli et al., 2015; Ioppolo et al., 2016). These requirements are strongly interrelated and imply all the territorial actors be involved to ensure the sustainable development of territory (Kloot & Martin, 2000; Barile et al., 2014).
By analysing banks’ communication strategies, it is possible to note that they ever more explicitly express their attention to the issues of territory highlighting their role in promoting its sustainable development (Scholtens, 2009; Sansone & Formisano, 2016).
However, this approach appears generally inspired more by the banks’ willingness to build profitable relationships with the market in the light of the dominant competition logic than by a true co-creation view (Bouma et al., 2001). In other words, this orientation does not seem to substantially change the view of their role in territory development.
With the aim of reinterpreting the traditional banks’ ‘service’ mission of sustaining the economic development of territories, in the light of a new ecosystems view, this work proposes an exploratory study directed to investigate the role of banks in promoting the sustainable development of territory also from a social and an environmental perspective (Hu & Scholtens, 2014). More specifically, the paper analyses the relevance of social development and environmental protection for a sample of Italian banks and its impact on territory development. Moreover, the paper investigates the propensity of banks to adopt a collaborative approach in favouring the emergence of a shared ecosystems view of territory development (Válek & Jašíková, 2013)
Flexible Measures in Magnetic Active Shielding
No full textBrowse Conference Publications > Electromagnetic Field Computa ...
Flexible measures in magnetic Active Shielding .This paper appears in:
Electromagnetic Field Computation (CEFC), 2010 14th Biennial IEEE Conference on
Date of Conference: 9-12 May 2010
Author(s): Formisano, A.
Dip. Ing. dell'Inf., Seconda Univ. di Napoli, Aversa, Italy
Lupoli, M.C. ; Martone, R.
Page(s): 1
Product Type: Conference Publications
5481633 searchabstract .Abstract
The reduction in protected regions of low frequency magnetic fields is a complex problem when the sources are not known. The paper proposes a procedure able to choose the best currents able to mitigate the disturbance field. The magnetic field is represented by suitable series of eigenfunctions in the domain of interest. The procedure includes a field identification step starting from a set of measurements and a current design step, possibly based on a preliminary design of specialized shimming coils sets
Tratti evolutivi della società della conoscenza: il contributo degli studi sulle reti nella prospettiva sistemica
No full textIl lavoro analizza l’evoluzione nella gestione della conoscenza al fine di individuare modelli e prospettive utili a consentire un miglioramento dell’efficienza nei processi di management. Il contributo offerto dalla letteratura è analizzato in considerazione delle logiche individuate dagli studi sulle Reti Sociali rilette alla luce del contributo interpretavo offerto dall’Approccio Sistemico Vitale (ASV) quale modello capace di evidenziare variabili e processi coinvolti nell’interazione tra le varietà informative di diversi sistemi. La sistematizzazione dei contributi in tema di gestione della conoscenza agevola la lettura e la comprensione dei modelli di management prevalenti delineando tratti e peculiarità della società della conoscenza – quale costrutto incentrato sulla relazione tra sistemi vitali – che gli approcci e gli strumenti tradizionali faticano a comprendere
Quaderni di Filologia romanza della Facoltà di Lettere e Filosofia dell'Università di Bologna (QFR).
No full textLa rivista occupa una posizione apprezzabile tra quante in Italia sono dedicate alla Filologia romanza, rispetto alle quali si contraddistingue per un' ampia apertura interdisciplinare, anzitutto nei confronti della Filologia germanica e della Storia medievale. Nel 2007 sono stati pubblicati i nn. 19 e 20: il primo (ufficialmente datato 2006) raccoglie gli Atti del Convegno (Bologna, 1-2 dicembre 2005) su "La traduzione è una forma. Trasmissione e sopravvivenza dei testi romanzi medievali" (a cura di Giuseppina Brunetti e Gabriele Giannini), cui si aggiungono tre saggi di romanistica; il secondo, raccoglie gli "Studi interdisciplinari di Filologia germanica" di GianGabriella Buti, a cura di Francesco Benozzo
Le imprese turistiche tra difficoltà e prospettive di sviluppo
No full textIl presente contributo1 si pone l’obiettivo di analizzare il fenomeno
turistico alla luce della chiave metodologica fornita dall’approccio
sistemico vitale, per verificare quali siano le condizioni ed i fattori che contribuiscono alla competitività degli operatori economici del settore.
Tra questi ci si riferirà, in particolare, alle imprese di minori dimensioni e si descriverà come l’impresa turistica, al pari delle altre imprese, dovrebbe essere propensa a fenomeni aggregativi che stimolano la interazione stabile tra operatori economici e dunque, dovrebbe considerare la propensione verso forme organizzative di tipo network tra imprese del territorio. In tale contesto si propone di individuare tre fattori critici a supporto della competitività delle imprese turistiche, proponendo una matrice concettuale di ausilio per la valutazione dei differenti pesi da attribuire ai fattori a seconda dei casi specifici. Il lavoro, infine, indaga sulle condizioni di vitalità del network tra imprese turistiche, ricercando i fattori determinanti che ne possano imprimere dinamiche competitive e favorire la fluidificazione dei processi di creazione del valore su base locale
Incremental Forming of Polycarbonate Sheets
No full textThe influence of the contact conditions at the tool-workpiece interface and the toolpath strategy on the quality of incremental formed parts made by polycarbonate sheets is investigated. To this end, different experimental tests were conducted involving different tool types (with fixed and rotating end) and toolpaths (unidirectional and alternate), to determine their influence on the material formability, twisting, elastic springback, forming forces, sheet thinning and surface roughness. The alternate toolpath enabled achieving the highest formability and minimum twisting, as compared to that observed when the unidirectional toolpath was used. On the other hand, the adoption of the tool with fixed end enabled reducing the springback, while the tool type showed negligible influence on the other quality parameters
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