132 research outputs found

    Seele, Verrücktheit, Intersubjektivität. Einige Überlegungen zu Hegels Anthropologie

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    The contribution aims at analyzing the first part of the Subjective Spirit, namely the Anthropology, trying to discover in the concept of Soul the first step of the Spirit, due to its intrinsic intersubjectivity. The first paragraph focuses on Hegel’s concept of the soul, which is characterized by immediacy and indeterminateness. These characteristics belong to the human being, as a spiritual being. The development of subjectivity is marked by negativity and contradiction. The highest contradiction is discussed in the second paragraph: insanity as an important moment for spiritual development. The soul, through insanity, as I try to argue in the third paragraph, recognizes partially the immanent and intersubjective relation that constitutes itself

    Seele, Verrücktheit, Intersubjektivität. Einige Überlegungen zu Hegels Anthropologie

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    Der Geist ist vom ersten Anfang an durch eine innere Intersubjektivität gekennzeichnet. Der erste Absatz zeigt die Hegelsche Konzeption der Seele: Unmittelbarkeit und Unbestimmtheit sind die ersten Merkmale einer Figur - der Seele -, die nicht mehr natürlich und nicht ganz geistig ist. Im zweiten Abschnitt geht es um die Rolle des Gefühls in der Bewegung der geistigen Selbstentwicklung, die zur Bildung des Subjekts führt. In diesem Satz zeigt sich die erste Form der Konzeptualisierung der Alterität. Im dritten Absatz geht es um die Hegelsche Konzeption des Wahnsinns und seine Rolle im geistigen Prozess. Der Wahnsinn erweist sich als "Symptom" der Intersubjektivität, die, obwohl von der Seele missverstanden, in der geistigen Welt grundlegend bleibt

    Nanostructured catalysts production through electrochemical methods: synthesis, characterization and possible applications

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    In this work a study of the electrochemical synthesis of TiO2 based nanostructured electrodes for photocatalytic and electrocatalytic applications is presented. The study on the electrochemical synthesis of TiO2 nanotubes (NTs) through anodization has been aimed to develop a novel “single-step” anodization method in symmetric electrochemical cells (i.e. both electrodes are Ti sheets), instead of traditional “double-step” processes, which include the sequence of two anodizations separated by the dissolution of the first formed TiO2 and are carried out in asymmetric cells with Pt electrocatalysts as counter electrodes. Besides the anodization, in relation to the specific applications discussed in this study, further electrochemical synthesis routes, employing the anodized TiO2 electrodes, were investigated. In photocatalytic applications, the electrodeposition of Cu2O nanoparticles over the surface of TiO2 NTs has been adopted as strategy to overcome the limited light absorption of the bare TiO2 photocatalyst (active only under UV irradiation). Here, in agreement with most of the studies among the available literature, under visible irradiation the TiO2/Cu2O based electrodes showed improved performances than the bare TiO2 (inactive under only visible light). These improved performances have been frequently claimed based on the only analysis of the photocatalytic performances under visible light, while in the present study it was found that, when the light source employed was UV + visible rather than only visible, the photo-catalytic performances of the composite electrodes were lower as compared to the bare TiO2 electrode. Furthermore, the bare TiO2 activity registered under UV + visible was higher than the composite electrode activity registered under only visible irradiation. To overcome this unexpected behaviour, at this stage the study has been aimed to the development of photo/electrochemical post-treatments, which allowed to improve the performances of the Cu2O based electrodes also under UV + visible light. Black TiO2 electrocatalysts were finally synthesized in the framework of the activities related to the e.THROUGH EU project (H2020-MSCA-RISE-2017-778045), which is aimed to the recovery of critical raw materials and sustainable remediation. Briefly, this goal would be achieved through the development of electrokinetic technologies for soil remediation, as in the case of the electrodialytic mine tailings remediation performed in this work. Electrodialytic remediation is generally carried out in symmetric cells which employ commercial Ti/MMO (Mixed Metal Oxides; Ir/Ru-based) electrodes, for both anode and cathode. Main limit for the real employment of these technologies are the energy costs related to the stirring and the power supply. Here, considering that the main reactions involved during the process are the water splitting reactions, one of the strategies to minimize the overall process cost is based on the recovery of the produced hydrogen. Considering that Ir-/Ru- based compounds are benchmark catalysts for the anodic reaction involved rather than the cathodic hydrogen evolution reaction, at this stage, the study has been aimed to the development of a non-commercial hydrogen evolution reaction (HER) electrocatalyst, namely the Black TiO2 based electrodes. These electrodes have been synthesized through the electrochemical reduction of the Ti/TiO2 electrodes resulting from the anodization, employing Ti sheets as counter electrodes

    ANIMA, FOLLIA, INTERSOGGETTIVITA: ALCUNE RIFLESSIONI SULL'ANTROPOLOGIA HEGELIANA

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    The article aims at analyzing the first part of the Subjective Spirit, namely the Anthropology, trying to discover the first step of the Spirit in the concept of soul, due to its intrinsic intersubjectivity. The first paragraph describes Hegel’s concept of soul, which is characterized by immediacy and indeterminateness. These characters belong to the human being as a spiritual being. The second paragraph concerns the concept of sensibility, which is connected to the Nature-Spirit gap. Sensibility is the first form of conceptualization of alterity. Through sensibility, soul begins to develop itself as subjectivity. This development is marked by negativity and contradiction. The highest contradiction is discussed in the third paragraph: insanity as an important moment for the spiritual development. In the fourth paragraph the author demonstrates that through insanity soul partially recognizes the immanent and intersubjective relation that constitutes itself

    «L’indicibile confusione». Carestia, pratiche e mercantilismi visti da Trieste (1764 e dintorni)

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    Nel 1763 e 1764, per cercare di affrontare la paventata crisi alimentare che si prospettava, il Regno di Napoli si rivolse a Trieste come via per rifornirsi dei cereali provenienti dall’Europa centrale e orientale. Il fallimento di questo tentativo fu una delle cause della carestia che colpì Napoli. L’autore, dal punto di vista di Trieste, ricostruisce le vicende di tale tentativo, cercando di far emergere gli interessi in campo, gli attori che ne furono protagonisti e le pratiche e le strategie da essi attuate. In tal modo la carestia diventa una “finestra eccezionale” che da un lato consente la narrazione degli eventi “in sé”, dall’altro permette di indagare sui meccanismi del mercato dei cereali e sulle relazioni esistenti tra il mondo del commercio e della finanza, quello dello stato e della burocrazia, quello dell’aristocrazia, quello della produzione, quello dell’applicazione e della creazione delle norme e quello dell’elusione e trasgressione. In 1763 and 1764, in the approach of the feared food crisis that lay ahead, the Kingdom of Naples turned to Trieste as a way to obtain cereals from Central and Eastern Europe. The failure of this attempt was one of the causes of the famine that struck Naples. From the point of view of Trieste, the author reconstructs the events of this attempt, trying to bring out the different interests confronting each other, the actors who were the protagonists and the practices and strategies implemented by them. In this way the famine becomes an "exceptional window". On the one hand it allows the analysis of the specific events. On the other it allows us to investigate the mechanisms of the cereals market and the relationships between the world of commerce and finance, that of the state and of the bureaucracy, that of the aristocracy, that of production, that of the application and creation of norms, and that of circumvention and transgression

    Evaluation of ultraviolet irradiation efficacy in an automated system for the aseptic compounding using challenge test

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    Objective: Ultraviolet (UV) irradiation efficacy in the intravenous compounding robot APOTECAchemowas evaluated to define the best operative conditions in terms of sterility and time optimization. Design: The challenge test was used against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis spores and Candida albicans. Inoculated plates were placed inside the robot and irradiated for different times. Microbial air and surface quality inside the equipment were monitored utilizing settle and contact plates, swabs. Results: After 4 h, no microorganisms were viable with killing rates ranging from 5-to 7-log for different microorganisms after 1 h of exposition. In confirmation of the efficacy of the UV irradiation program adopted, the microbial monitoring inside the equipment always gave negative results. Conclusions: This is the first exhaustive investigation of UV irradiation efficacy in the aseptic pharmaceutical production. We demonstrated that UV irradiation plays an essential role in maintaining the sterility condition of the workplace inside the APOTECAchemo and assuring the standards for aseptic manufacturing of medicinal drugs, as required for Class A clean areas. A 4-h UV irradiation also ensures sterility in the case of very resistant microorganisms and in the presence of high microbial charge (108 CFU/ml), but a killing rate of 5 or more is already recorded after the first hour of exposition. The results provide useful information for the best operative conditions in terms of both sterility and time optimization, not only for the automated compounding, but also for the traditional aseptic manufacturing processes. © The Author 2015. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved

    Hypersensitivity reactions to food and drug additives: problem or myth?

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    BACKGROUND AND AIM OF THE WORK: The possibility of an allergic reaction or an intolerance to additives is frequently suspected by parents, especially for chronic illness with frequent exacerbations such as atopic dermatitis or chronic urticaria. For more than 50 years, potential adverse reactions to additives have been suggested, but to date data are conflicting. The purpose of this article is to provide the clinicians with general information about additives and adverse reactions to them and to suggest a practical approach to children suspected to have reactions to food additives. METHODS: We performed an extensive research on all English-language Medline articles, case reports and reviews published online until December 2018. Used search terms were: food additives, food dye, adverse reactions, food allergy, food hypersensitivity, intolerance, drugs, children. RESULTS: There are only few case reports of adverse reactions in childhood with a clear involvement of additives. In this review article we reported the associations between additives and adverse reactions described in literature, in order to inform the pediatrician about the potential clinical manifestations. CONCLUSIONS: Prior to suspect an adverse reaction to additives, it is important to rule out other possible causes: the diagnostic process is complicated and rarely conclusive. The gold standard is the double-blind placebo controlled oral challenge after an exclusion diet

    VEGFA gene locus (6p12) amplification and colorectal cancer : implications for patients' response to therapy

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    The aims of this study was to assess the presence of VEGFA genomic alterations in colorectal cancer (CRC) and clarify how these genomic alterations can modulate CRC patients’ response to BV treatment in addition to first line therapy (5fluorouracil, leucovorin, capecitabine, oxaliplatin, mephedrone). Among our goals we aim to find out predictive biomarkers to improve anti-angiogenic therapy efficacy and possibly to develop new therapeutic approaches by setting out new rational drug combinations. Of importance, this study allowed us to contribute to the improving patient’s treatment efficiency as well as reducing the economic cost of ineffective therapy. To conclude, we believe that CRC patients will greatly benefit from our research activities. Altogether, our study helped the setting of personalized therapeutic strategies by: i) identifying those patients who really will profit of BV treatment, ii) sparing unnecessary side effects and costs for the non-responder CRC patients especially and iii) planning future alternative and/or combination treatments for CRC patients based on the functional results

    3D Dental Reconstruction with Photogrammetry Technology

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    In the dental field, the use of digital technologies for scanning of the hard and soft tissues of the mouth is becoming more and more widespread. The availability of digital 3D models of the dental arches allows to plan treatments and to show the results in advance, increasing patient confidence. However, currently in clinical practice, the accuracy of digital models, although very satisfactory, does not reach that of traditional impressions. It also requires the use of technologies that simplify the hardware structure, making the intraoral acquisition device more manageable and comfortable. The purpose of this study is to evaluate how photogrammetry technology, commonly and widely used and very effective in other sectors, can be adapted to the dental field, starting from the reconstruction of a dental plaster cast. By comparing the 3D model obtained with the proposed technology with a 3D model obtained using the leading top player intraoral scanners on the market, comparable results were obtained in terms of reconstruction performance. Both from the comparison of the spatial alignment and from the comparison of the shape, a certain overlap and equality between the two 3D models emerge. These results suggest that this technology could represent a valid solution for the 3D models reconstruction also in the dental field, overcoming the limitation of technologies currently used on the market in this field
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