1,720,996 research outputs found
Inhibitory activity of Lactobacillus plantarum P17630 against Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae
No full textBACKGROUND: The antimicrobial properties associated with lactic acid bacteria having probiotic activities have been confirmed by numerous studies. The urinary and urogenital tracts are often subjected to bacterial infections caused for about 80% by Escherichia coli, and for 20% by other bacteria including Proteus mirabilis and Klebsiella pneumoniae. The excessive use of antibiotics to eradicate these infections has contributed enormously to the development of antibiotic resistances. Therefore, the use of probiotics represents not only an important alternative but also an ethical and sustainable choice. METHODS: This study evaluated the antibacterial activity of the probiotic LAB Lactobacillus plantarum P17630 against Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae by means of the agar spot method and the agar plug diffusion test. RESULTS: Lactobacillus plantarum P17630 showed strong inhibitory activity against various strains of Escherichia coli with inhibition halos ranging between 3.80 cm and 5.09 cm, strong inhibitory activity against Klebsiella pneumoniae and intermediate against Proteus mirabilis, with average inhibition halos of 3.98 cm and 1.20 cm, respectively. CONCLUSIONS: These results confirmed the antimicrobial activity of Lactobacillus plantarum P17630 against Escherichia coli and its antibacterial activity against other bacteria implicated in urinary tract infections and vaginal infection, suggesting its wider therapeutic use in this field
Injectable scaffolds enriched with silver to inhibit bacterial invasion in tissue regeneration
No full text
Diverse effects of natural and synthetic surfactants on the inhibition of staphylococcus aureus biofilm
Full text linkA major challenge in the biomedical field is the creation of materials and coating strategies that effectively limit the onset of biofilm-associated infections on medical devices. Biosurfactants are well known and appreciated for their antimicrobial/anti-adhesive/anti-biofilm properties, low toxicity, and biocompatibility. In this study, the rhamnolipid produced by Pseudomonas aeruginosa 89 (R89BS) was characterized by HPLC-MS/MS and its ability to modify cell surface hydrophobicity and membrane permeability as well as its antimicrobial, anti-adhesive, and anti-biofilm activity against Staphylococcus aureus were compared to two commonly used surfactants of synthetic origin: Tween® 80 and TritonTM X-100. The R89BS crude extract showed a grade of purity of 91.4% and was composed by 70.6% of mono-rhamnolipids and 20.8% of di-rhamnolipids. The biological activities of R89BS towards S. aureus were higher than those of the two synthetic surfactants. In particular, the anti-adhesive and anti-biofilm properties of R89BS and of its purified mono-and di-congeners were similar. R89BS inhibition of S. aureus adhesion and biofilm formation was ~97% and 85%, respectively, and resulted in an increased inhibition of about 33% after 6 h and of about 39% after 72 h when compared to their chemical counterparts. These results suggest a possible applicability of R89BS as a protective coating agent to limit implant colonization
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Self-polymerizing DOPA as a functional layer for the development of antimicrobial coating on PTFE barrier membranes for GTR procedures
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
