1,721,142 research outputs found
Functional diversity of L-type calcium channels in rat cerebellar neurons
No full textSingle-channel recordings show that functionally different L-type Ca2+ channels coexist in rat cerebellar granules. Besides two different dihydropyridine (DHP)sensitive gating patterns with properties similar to those of cardiac L-type channels, cerebellar granules contain a third DHP-sensitive gating pattern with unusual voltage-dependent properties and slightly different conductance. This ''anomalous gating'' is characterized, on one hand, by rare, short openings with very low open probability even at high positive voltages and, on the other hand, by long openings with high open probability at negative voltages after a predepolarization. L-type channels with anomalous gating appear suited to generate a surge of Ca2+ influx following strong neuronal activity. The anomalous gating can be explained by a model in which voltage controls the equilibrium between two gating modes
Il "misterioso salto" dalla psiche al soma. Rassegna essenziale di concetti sull'approccio psicoanalitico al disturbo psicosomatico.
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Le Creme delle Streghe
No full textIl saggio (ri)scopre erbe e piante medicinali rintracciate nei manoscritti medievali come antichi rimedi tramandati per generazioni soprattutto dalle donne. Principali custodi di un incredibile patrimonio curativo, terapico e farmacologico, fondato su conoscenze naturali e senza basi scientifiche, furono avversate e perseguitate durante la famigerata "caccia alle streghe" proprio per questo. Il complesso lavoro di ricerca sui manoscritti ha permesso di scovare una quantità enorme di rimedi domestici, medici e veterinari di una modernità impressionante. Per esempio, si conoscevano già l'efficacia della bava di lumaca o delle lacrime di vite, un metodo per lo sbiancamento dei denti ed unguenti per le ustioni. Le ricette sono state tradotte, decifrate e studiate dagli autori, che rivedendo e modificando la composizione, gli ingredienti ed il procedimento botanico-farmaceutico, hanno dato nuova vita a rimedi naturali che conservano la forza di secoli di sapienza
Mechanisms of spontaneous miniature activity at CA3-CA1 synapses: evidence for a divergence from a random Poisson process
No full textRUTHENIUM-CATALYZED OXIDATION OF ALKYLAROMATICS BY MONOPERSULFATE WITH PREFERENTIAL OXIDATIVE FISSION OF THE BENZENE-RING
No full textEthylbenzene and a number of alkylbenzenes variously substituted at the alkyl chains, i.e. benzyl alcohol, benzaldehyde, benzoic acid, benzonitrile, benzyl chloride and benzyl bromide, undergo effective oxidative fission of the benzene ring to carbon dioxide and water when reacting at room temperature with aqueous persulfate in the presence of catalytic amounts of ruthenium derivatives
Misure di prevenzione e presunta pericolosità dei beni
No full textLa discplina delle misure di prevenzione patrimoniali e la pericolosità presunta del patrimonio del propost
Changes of N-Methyl-D-Aspartate activated channels of cerebellar granule cells with days in culture
No full textSound perception and its effects in plants and algae
No full textLife evolved in an acoustic world. Sound is perceived in different ways by the species that inhabit the Planet. Among organisms, also some algal species seem to respond to sound stimuli with increased cell growth and productivity. The purpose of this Short Communication is to provide an overview of the current literature about various organisms and sound, with particular attention to algal organisms, which, when subjected to sound applications, can change their metabolism accordingly
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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