3,690 research outputs found
Self-compression of 4.9 µm pulses to sub-40 fs with 2 mJ energy in Zinc Sulfide
No full textNonlinear self-compression of few-cycle multi-mJ pulses at 4.9 µm in ZnS is presented. 80 fs input pulses are compressed to 37 fs with 2.1 mJ energy at a 1 kHz repetition rate. © 2024 The Author(s
The hereditary angioedema burden of illness study in Europe (HAE-BOIS-Europe) : background and methodology
No full textBackground: Hereditary angioedema (HAE) is a rare but serious disease marked by swelling attacks in the extremities, face, trunk, airway, or abdominal areas that can be spontaneous or the result of trauma and other triggers. It can be life-threatening due to the risk of asphyxiation. While there have been major advancements in our understanding of the immunogenetics of HAE, there are significant gaps in the literature regarding understanding of the humanistic and economic impact of the disease, particularly in Europe. The purpose of the HAE Burden of Illness Study-Europe (HAE-BOIS-Europe), the development and methodology of which is described here, is to better understand the management and impact of HAE from the patient perspective in Europe.
Methods/Design: This is a cross-sectional study in which retrospective data were also collected being conducted in Denmark, Germany and Spain. The study is open to patients ages 12 and older with a diagnosis of HAE-I or HAE-II. Data collection includes: (i) a survey on individuals’ health care resource use, direct and indirect medical costs, impact on work and school, treatment satisfaction, and emotional functioning (via the Hospital Anxiety and Depression Scale); and (ii) one-on-one interviews to collect detailed descriptive data and patient testimonials on the impact of HAE on patients’ health-related quality of life.
Discussion: The present manuscript describes the development and plans for implementing a multi-country European study with the aim of characterizing the humanistic and economic burden of HAE from the patient perspective. This study will help raise awareness of HAE as a rare but debilitating condition with wide-ranging impacts
Almeida, MJ, Forjaz, MA, Almeida Aguiar, C. Um 100 número de Scientiae em objetos do dia a dia. SciCom 2017 - Objetos de Ciência. pp
No full textinfo:eu-repo/semantics/publishedVersio
Correction to: Chamoun et al., Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection
No full textChamoun MN, Blumenthal A, Sullivan MJ, Schembri MA, Ulett GC. 2018. Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology. https://doi.org/10.1080/1040841X.2018.1426556.
When the above article was first published online, the below three corrections were missed.
The author ‘Antje Blumenthal’ was wrongly affiliated to the affiliation “cSchool of Chemistry and Molecular Biosciences, and Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Australia”. Now this affiliation has been removed for this author.
The affiliation ‘bTranslational Research Institute, The University of Queensland Diamantina Institute, Woolloongabba, Australia’ of the author ‘Antje Blumenthal’ should read ‘bThe University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia’.
In Table 3, the sentence ‘Benefit of manipulating IL-17 levels to improve immunization strategies M. tuberculosis’ should read “Benefit of manipulating IL-17 levels to improve immunization strategies against M. tuberculosis”.No Full Tex
Generation of 22-mJ, 2.0-ps Pulses from a 1-kHz Ho:YLF Regenerative Chirped Pulse Amplifier
No full textWe report a CW-pumped Ho:YLF regenerative amplifier (RA) delivering pulses with 22.5-mJ energy and 2.0-ps duration at 1 kHz. The RA emitting at 2051 nm is broadband-seeded and implemented in a chirped pulse amplification system. © 2024 The Author(s
ICF-Based Disability Survey in a Rural Population of Adults and Older Adults Living in Cinco Villas, Northeastern Spain: Design, Methods and Population Characteristics
No full textBackground: This article describes the methods of a door-to-door screening survey exploring the distribution of disability and its major determinants in northeastern Spain. This study will set the basis for the development of disability-related services for the rural elderly in northeastern Spain. Methods: The probabilistic sample was composed of 1,354 de facto residents from a population of 12,784 Social Security card holders (age: 6 50 years). Cognitive and disability screenings were conducted (period: June 2008-June 2009). Screening instruments were the MMSE and the World Health Organization Disability Assessment Schedule. Participants screened positive for disability underwent an assessment protocol focusing on primary care diagnoses, disability, lifestyle, and social and health service usage. Participants screened positive for cognitive functioning went through in-depth neurological evaluation. Results: The study sample is described. Usable data were available for 1,216 participants. A total of 625 individuals (51.4%) scored within the positive range in the disability screening, while 135 (11.1%) scored within the positive range of the cognitive screening. The proportion of positively screened individuals was higher for women and increased with age. Conclusions: Screening surveys represent a feasible design for examining the distribution of disability and its determinants among the elderly. Data quality may benefit from methodological developments tailored to rural populations with a low education level. Copyright (C) 2010 S. Karger AG, Base
Pure-rotational 1D-CARS spatiotemporal thermometry with a single regenerative amplifier system
No full textWe report spatiotemporal pure-rotational coherent anti-Stokes Raman spectroscopy (CARS) in a one-dimensional imaging arrangement obtained with a single ultrafast regenerative amplifier system. The femtosecond pump/Stokes photon pairs, used for impulsive excitation, are delivered by an external compressor operating on a ∼35% beam split of the uncompressed amplifier output (2.5 mJ/pulse). The picosecond 1.2 mJ probe pulse is produced via the second-harmonic bandwidth compression (SHBC) of the ∼65% remainder of the amplifier output (4.5 mJ/pulse), which originates from the internal compressor. The two pump/Stokes and probe pulses are spatially, temporally, and repetition-wise correlated at the measurement, and the signal generation plane is relayed by a wide-field coherent imaging spectrometer onto the detector plane, which is refreshed at the same repetition rate as the ultrafast regenerative amplifier system. We demonstrate 1 kHz cinematographic 1D-CARS gas-phase thermometry across an unstable premixed methane/air flame-front, achieved with a single-shot precision <1% and accuracy <3%, 1.4 mm field of view, and an excellent <20 µm line-spread function.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Flight Performance and Propulsio
Project: Establishing an accounting outsourcing company "MJ Grāmatvedība" Ltd
No full textProjekta ideja ir izveidot grāmatvedības ārpakalpojumu uzņēmumu SIA „MJ Grāmatvedība”, kurš sniegtu pilna vai daļēja cikla grāmatvedības pakalpojumus, sākot ar pirmreizējo dokumentu apstrādi un beidzot ar visu nepieciešamo atskaišu sagatavošanu, kā arī konsultāciju sniegšanu. Projekta mērķis ir ne tikai sniegt grāmatvedības pakalpojumus, bet arī analizēt uzņēmumu darbību un izstrādāt ieteikumus darbības uzlabošanai. Darba autore uzskata, ka nozares pārstāvjiem ir būtiski jāpierāda sava nozīme un to kādam jābūt mūsdienu grāmatvedim. Grāmatvedis nav tikai persona, kura izdara konkrētus darbus, nodos atskaites, tas ir cilvēks, kuram labi jāpārzina nodokļu sistēma, finanšu vadīšana, jāspēj sniegt padomus uzņēmuma finanšu vadības uzlabošanai, kā arī jāspēj pielāgoties tehnoloģiju radītajām izmaiņām. Maģistra darbs apjoms ir uz 105 lappusēm, kas sastāv no 7 nodaļām, 17 pielikumiem, 22 tabulām un 7 attēliem. Darba izstrādē izmantoti 70 informācijas avoti.The general project idea is to establish the accountancy firm MJ Accountancy Ltd., which would provide full or half-cycle accountancy services including the processing of primary documentation, reports’ preparation, and providing of the accountancy consultations. The aim of the project is not only to provide accountancy consultations but also to deal with firms activity analysis and developing suggestions on their activity improvement. The author of the project supports the idea that the field representatives must constantly sustain the status of the accountant’s profession in current times. The accountant is not only the person who executes one’s regular duties and submits reports, but also the person who is competent in the field of taxes, financial management, able to advise on improvements in financial management, and above all able to adapt to the technological changes. The volume of the project is 105 pages, which includes 7 chapters, 17 appendices, 22 tables, 7 figures. 70 sources of information were used in master’s thesis
Initial state and transition-state solvation effects in the cobaltotungstate oxidation of iodide in binary aqueous solvent mixtures
No full textPT: J; CR: AMJAD Z, 1977, CAN J CHEM, V55, P3581 BAKER LCW, 1956, J AM CHEM SOC, V78, P4503 BECK MT, 1968, COORDIN CHEM REV, V3, P91 BLANDAMER MJ, UNPUB CAN J CHEM BLANDAMER MJ, 1978, J CHEM SOC CHEM COMM, P963 BLANDAMER MJ, 1979, PURE APPL CHEM, V51, P2087 BLANDAMER MJ, 1980, COORDIN CHEM REV, V31, P93 BLANDAMER MJ, 1980, J CHEM SOC DA, P1 BLANDAMER MJ, 1980, J CHEM SOC DA, P2442 BRODOVITCH JC, UNPUB BURGESS J, 1968, J CHEM SOC A, P2571 BURGESS J, 1970, J CHEM SOC A, P2111 BURGESS J, 1970, J CHEM SOC A, P2351 BURGESS J, 1972, INORGANIC REACTION M, V2, P127 BURGESS J, 1973, J CHEM SOC A, P825 BURGESS J, 1974, INORGANIC REACTION M, V3, P142 BURGESS J, 1977, INORGANIC REACTION M, V5, P158 BURGESS J, 1979, INORGANIC REACTION M, V6, P168 COX BG, 1974, ANN REP CHEM SOC A, V71, P249 COX BG, 1979, J CHEM SOC F1, V75, P1780 COX BG, 1979, J CHEM SOC FARAD T 1, V75, P86 DELIGNY CL, 1965, RECL TRAV CHIM PAY B, V84, P81 ELLIS KJ, 1973, J CHEM SOC DA, P1533 GRUNWALD E, 1948, J AM CHEM SOC, V70, P846 KANEMAQUIRE LAP, 1975, J CHEM SOC DA, P1890 KEPERT DL, 1978, J CHEM SOC DA, P137 MARCUS RA, 1968, J PHYS CHEM-US, V72, P891 PELIZZETTI E, 1976, INORG CHEM, V15, P2898 SUBHANI MS, 1978, REV ROUMAINE CHIM, V23, P719 UDOVENKO VV, 1977, RUSS J INORG CHEM, V22, P168 WELLS CF, 1973, J CHEM SOC FARAD T 1, V69, P984 WELLS PR, 1968, LINEAR FREE ENERGY R, CH4; NR: 32; TC: 14; J9: TRANSIT METAL CHEM; PG: 4; GA: NG073Source type: Electronic(1
An extension of the weighted sum of gray gases non-gray gas radiation model to a two phase mixture of non-gray gas with particles
No full textA great deal of efforts has been exercised to date to accurately model the non-gray behavior of the gases. Among others, the weighted sum of gray gases model (WSGGM), which replaces the non-gray gas behavior by an equivalent finite number of gray gases, is a simplified model yielding reasonable results. However, a discussion on the weighting factors required for an estimation of radiation in a mixture of non-gray gas/gray particulate is not yet established for WSGGM, since they are dependent on the particle number density, particle size distribution: local temperature and partial pressure. Consequently, the relation between the weighting factors used in the WSGGM for a mixture of non-gray gas and gray particles with scattering in the thermal non-equilibrium has been discussed here, which has not been done before to the author's best knowledge. Weighting factors for the particles, of which temperature is different from that of the gas, were evaluated analytically for the WSGGM. The results were, then, validated for the problem of isothermal gas containing soot particulates between two parallel slab walls. For further application, the approach derived here was implemented to examine the non-gray radiative effects of the two phase mixture in an axisymmetric cylinder by changing such various parameters as the particle temperature, non-gray gas composition and particle concentration. The effects of thermal non-equilibrium in a mixture of gas and particles were also discussed in parallel with scattering effects by particles. Parametric study showed that a variation in the gas concentration yielded a noticeable change in the radiative heat transfer when the suspended particle temperature was different from the gas temperature. New contribution of this study consisted in an extension of applicability of the WSGGM non-gray model to two phase radiation. (C) 2000 Elsevier Science Ltd. All rights reserved.The authors wish to acknowledge the financial support of the Korea Research Foundation made in the program year of 1998 under the contract 1998-018-E00016
- …
