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An integrative developmental psychopathology approach to depression
This chapter aims to describe an integrative developmental psychopathology approach to the conceptualization and treatment of depression. Based on evolutionary and developmental psychopathology approaches, we discuss empirical findings concerning three biobehavioral systems that are central in depression: stress or emotion regulation, reward, and mentalizing or social cognition. We discuss interrelated disturbances in each of these biobehavioral systems and how they typically lead to developmental cascades involved in depression. We focus on the impact of these interacting impairments on normative developmental tasks that rely on capacities associated with each of the three biobehavioral systems. We highlight the importance of adolescence and early adulthood, as these developmental phases involve the need to establish a new balance between relatedness and agency/autonomy, capacities that rely heavily on the stress-regulation, reward, and mentalizing systems. We also discuss how this approach sheds a new light on the high comorbidity between depression and other psychiatric and (functional) somatic disorders. Finally, we consider the implications of these views for prevention and intervention approaches
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