30,408 research outputs found
Introduction to "Core-shell nanostructures for drug delivery and theranostics: Challenges, strategies, and prospects for novel carrier systems"
No full textNo abstract availabl
Dataset on biomimetic hierarchically arranged nanofibrous structures resembling the architecture and the passive mechanical properties of skeletal muscles: a step forward towards artificial muscles
No full textThe present database contains the data presented and discussed in the paper “Biomimetic hierarchically arranged nanofibrous structures resembling the architecture and the passive mechanical properties of skeletal muscles: a step forward towards artificial muscle” by Carlo Gotti, Alberto Sensini, Gianmaria Fornaia, Chiara Gualandi, Andrea Zucchelli and Maria Letizia Focarete, accepted for publication in the journal Frontiers in Bioengineering and Biotechnology (2020, doi 10.3389/fbioe.2020.00767). The paper describes an approach for the biomimetic design of engineered muscle, that makes use of an elastomeric polyurethane with suitable mechanical performances, processed with the electrospinning technology, to produce a hierarchically arranged nanofibrous structure resembling the architecture and passive biomechanical properties of skeletal muscles. Scaffolds morphology and physical properties are studied and a detailed analysis of material mechanical properties is performed, taking into account the different levels of increasing complexity, going from mats to bundles and finally the hierarchical nanofibrous electrospun structure (HNES). Data include the thermal characterization of the pristine PU pellets (thermogravimetric and differential scanning calorimetry analysis), force-displacement data obtained through mechanical tensile tests along with the different geometrical and physical characterization of the samples, the results of the mechanical characterization, data on the nanofibrous alignment and the outcome of a statistical analysis
Core-shell nanostructures for drug delivery and theranostics: Challenges, strategies, and prospects for novel carrier systems
No full textCore-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry
Advances in multidrug delivery from electrospun nanomaterials
No full textMultidrug delivery systems are attracting increasing interest nowadays given their great potential as a novel therapeutic combination for different diseases, including cancer. Many different approaches have been explored to create a library of multidrug systems with controlled release kinetics, able to fulfill most medical demands. In this context electrospinning, due to its versatility, represents a valuable technique to load multiple active agents into polymeric nano-microfibers. A broad range of synthetic and natural polymers can be processed into electrospun fibers, allowing the development of drug delivery systems with a broad spectrum of different chemical and physical properties. In this chapter three main methods, (1) monolithic electrospun fibers, (2) core-sheath fibers, and (3) electrospun fibers loaded with nanocarriers, will be discussed in detail, underlining the pros and cons of each technique and discussing the most representative examples reported in literature
Filtering media by electrospinning: Next generation membranes for separation applications
No full textThis book covers the state-of-the-art on electrospun materials for the use of filters for water remediation, ion-exchange membranes and affinity membranes for the capture of selected chemical and biochemical species, as well as filtering applications covering air treatment, defense and protective applications, and oil-water separation. The book also provides an overview of the landscape of marketed electrospun filters and of technical approaches for the large scale production of nanofibrous non-woven filter media. This is an ideal book for biomaterials and polymer researchers interested in the applications of filtering media by electrospinning. This book also: Covers the latest research on ion-exchange membranes and affinity membranes for capture of cells and biological substances. Broadens reader understanding of antimicrobial electrospun filters and sieving filters for liquid microfiltration. Reviews exhaustively the key recent research into electrospun filters for oil-water separation, heavy metals removal, and defense and protective applications
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