1,720,971 research outputs found
Dal Laboratorio al paziente
No full textIl capitolo descrive l'iter di sviluppo di un farmaco antiepilettico nelle sue varie tappe in laboratorio e successivamente sul paziente
Improving comfort of a new city vehicle by means of parameter design in virtual environment
No full textOslo, Norwa
Improving comfort of a new city vehicle by means of parameter design in virtual environment
No full textOslo, Norwa
Le soste climatizzate
No full textIl contributo propone una esperienza progettuale di bioclimatica nell'area sorrentina
On the Crashworthiness Behaviour of Innovative Sandwich Shock Absorbers
No full textIncreasing the impact resistance properties of any transport vehicle is a real engineering challenge. This challenge is addressed in this paper by proposing a high-performing structural solution. Hence, the performance, in terms of improvement of the energy absorbing characteristics and the reduction of the peak accelerations, of highly efficient shock absorbers integrated in key locations of a minibus chassis have been assessed by means of numerical crash simulations. The high efficiency of the proposed damping system has been achieved by improving the current design and manufacturing process of the state-of-the-art shock absorbers. Indeed, the proposed passive safety system is composed of additive manufactured, hybrid polymer/composite (Polypropylene/Composite Fibres Reinforced Polymers—PP/CFRP) shock absorbers. The resulting hybrid component combines the high stiffness-to-mass and strength-to-mass ratios characteristic of the composites with the capability of the PP to dissipate energy by plastic deformation. Moreover, thanks to the Additive Manufacturing (AM) technique, low-mass and low-volume highly-efficient shock-absorbing sandwich structures can be designed and manufactured. The use of high-efficiency additively manufactured sandwich shock absorbers has been demonstrated as an effective way to improve the passive safety of passengers, achieving a reduction in the peak of the reaction force and energy absorbed in the safety cage of the chassis’ structure, respectively, up to up to 30 kN and 25%
A Feasibility Study on Innovative Reinforced Modular Frames for Automotive Applications
No full textVehicle frames can be considered the main stiffening component being, at the same time, functional hubs for all the other components assembly. Frames’ main goal is to absorb the static and dynamic loads acting on the vehicle, ensuring passengers’ safety. In this paper a feasibility study on an innovative modular frame concept is presented. An attempt has been made to design a modular frame by using customized additive manufacturable steel joints. Actually, standard frame structures are manufactured by welding separated tubes, making access to some internal areas of the vehicle very difficult where not impossible. Consequently, some maintenance operations become also challenging. The modular configuration solves these maintenance problems enabling, at the same time, to start thinking about multi-purposes vehicle configurations, which can be switched by simply changing the modules connected to a central cell. Reinforced panels have been, also, integrated into the modular frame, which contribute to torsional stiffness with an overall mass reduction. The concept of a modular frame with collaborating reinforced panels, has been preliminary demonstrated by means of numerical simulations within the ABAQUS FEM environment. Certification torsional loads have been applied to the modular reinforced frame and the obtained numerical results contributed to prove the feasibility and the effectiveness of the proposed design
IBIS PROJECT: THE INNOVATIVE, SUSTAINABLE AND INTEGRATED BUS
No full textThe paper presents the results of studies on sustainable mobility, conducted by a multidisciplinary research group. The aim of the activity is to design and assemble a totally modular and innovative bus. This vehicle, designed for sustainable mobility in Italian cities and sites of monumental artistic interest, is equipped with the latest generation of electric motors and batteries. It will therefore be made with environmentally friendly materials. The project aligns with the most recent European research lines on the theme “Building an integrated intelligent transport system”. The methodological approach used is oriented towards the creation of a “collaborative ecosystem” between re- searchers and companies for the definition of a working prototype. The work is in line with the European guide on eco-sustainability of products, the reduction of pollution in urban centers and the so-called “circular economy” that minimizes the risk of non-recyclable waste. The project includes the main specialized multidisciplinary sectors
On the Use of a Hybrid Metallic-Composite Design to Increase Mechanical Performance of an Automotive Chassis
No full textThanks to the introduction of high-performance composite materials, 'metal replacement' approaches are successfully gaining ground even in the most challenging engineering applications. Among these, one of the most recent application challenges is improving the driving range of Battery Electric Vehicles (BEVs) by adopting innovative materials to lighten the mass of structural components, thus reducing energy requirements and enabling the use of smaller and less expensive batteries. Hence, in the present work, the employment of laminated composite panels in an electric minibus chassis is investigated as an effective way to reduce the global mass of the chassis’ structure and, at the same time, to increase its structural performances in terms of torsional stiffness and crashworthiness. By replacing specific steel tubulars with carbon-fiber-reinforced polymer (CFRP) laminated composite structures, different chassis configurations were numerically developed and detailed simulations to compare both masses and mechanical responses were carried out. The paper proves that with this approach it is possible to lighten the chassis up to 9%, while achieving a 7% increase in torsional stiffness and a 9% increase in Specific Energy Absorption (SEA)
EEG discharges on awakening: A marker of idiopathic generalized epilepsy.
No full textIn a series of 24-hour ambulatory EEG recordings from
1,000 consecutive adult outpatients (44.5% with generalized and 55.5% with
partial epilepsy, one recording per patient), the authors found only 46 (4.6%)
activations of epileptiform discharges on awakening. All recordings came
from patients with idiopathic generalized epilepsy, predominantly with juvenile
myoclonic epilepsy and generalized tonic-clonic seizures on awakening. Multiple
spike discharges that develop with an unusually delayed onset after arousal
(more than 10 minutes) might help to discriminate juvenile myoclonic epileps
- …
