1,247 research outputs found
Correlation between Tumour Associated Macrophage (TAM) Infiltration and Mitotic Activity in Canine Soft Tissue Sarcomas†
No full textTumour-associated macrophages (TAMs) are an important part of the tumour microen-vironment but knowledge of their distribution in canine soft tissue sarcomas (STSs) is limited to absent. We analysed 38 STSs retrieved from the veterinary pathology archive; oral and visceral STSs, synovial cell sarcoma, tumours of histiocytic origin, haemangiosarcoma, carcinosarcomas, and undifferentiated tumours were excluded. Iba-1 positive, non-neoplastic tumour infiltrating cells (morphologically indicative of macrophages) were classified as TAMs and were counted in 10 consecutive tumours areas, where no necrosis or other inflammatory cells could be identified. Associations between numbers of TAMs and mitoses, differentiation, and necrosis scores or grade were investigated. TAMs were evident in all STSs and ranged between 6% to 62% of the cells in the microscopic field. The number of TAMs positively correlated with the STSs’ histologic grade. When the components of the grade were analysed separately, TAMs were statistically correlated with mitoses, but not with differentiation or necrosis score. The present findings suggest that TAMs are present in higher numbers when STS proliferation is the predominant feature that drives tumour grade. The abundant presence of TAMs in high-grade STSs may also increase the likelihood of a pathologist misdiagnosing STS for histiocytic sarcoma
Giulia Veronica Varisco
No full textThe headword explains the biography and the contribution of the author Giulia Varisco to the children's literatur
Outcomes of self-control plans on acrylamide levels in processed food
No full textIn 2002, researchers from Stockholm University discovered the presence of acrylamide (AA) in processed foods. This substance has been classified as “probably carcinogenic to humans” by the International Agency for Research on Cancer. In response to the alarming finding, the European Commission issued recommendations (2004/394/EC, 2010/307/EU, and 2013/647/EU), guiding food business operators, raising awareness, and promoting good manufacturing practices to minimize AA formation. These efforts laid the foundation for the comprehensive measures in Regulation (EU) 2017/2158. The Regulation implemented specific measures during production to reduce the amount of AA in food. This study monitored the AA levels in 15,674 samples from 12 processed food commodities. Potato-based products and coffee were found to be the main sources of AA exposure. The “baby foods” and “soft bread” food categories had the lowest contamination levels. The data were then compared to the information previously published by the European Food Safety Authority to assess the trend over time and the effectiveness of the mitigation measures. The results showed a decrease in AA contamination levels for most food categories, particularly for baby foods
Regenerating Iron via Electrolysis for CO2-Free Energy Storage and Carrier
No full textTo tackle the intermittency problem in renewable energy usage, it is necessary to develop sustainable energy storage and transportation technologies. One such solution is the use of iron powder as an energy carrier, which enables flexible energy usage. The combustion process releases the energy stored in iron powder while the solid product, i.e., iron oxide can be easily collected and then reduced to metallic iron, enforcing a recyclable iron fuel cycle (Fig.1). We investigate the use of electrochemical technique for iron regeneration in the context of the iron fuel cycle [1-4]. The laboratory-scale experiments with parallel plate electrolyzer using aqueous NaOH (50%wt, 18 M) suspended with micron-sized Fe2O3 (hematite) powder are conducted in the present work. We study the electrochemical performance and deposition behavior of the iron, exploring different parameters such as current density, iron oxide concentration, temperature, NaOH concentration, and powder size, with the aim of achieving optimal Faradaic efficiency. A high Faradaic efficiency (>90%) and high iron purity cathodic deposition have been achieved in relatively low electrical energy consumption (less than 6 kWh/kg). The metallic iron is deposited in the form of unique dendritic structures on the cathode. (Fig. 2). The dendrites are located primarily on the side and edge of the cathode, indicating a diffusion-controlled mechanism. This structure makes it easy for direct harvest of the iron powder. A new reactor design with a rotating disc as a cathode is proposed to realize continuous electrolytic iron powder production [4]. The obtained results open new perspectives for the completion of the iron fuel cycle, by enabling a sustainable regeneration of iron.References:[1] N.van Graefschepe, A.I. Majid, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. NPS 17 Delft.[2] A.I. Majid, N.van Graefschepe, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. 32nd ISE Topical Meeting.[3] A.I. Majid, N.van Graefschepe, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. In preparation.[4] A.I. Majid, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. US Provisional Patent, 63/363,627<br/
Regenerating Iron via Electrolysis for CO2-Free Energy Storage and Carrier
No full textTo tackle the intermittency problem in renewable energy usage, it is necessary to develop sustainable energy storage and transportation technologies. One such solution is the use of iron powder as an energy carrier, which enables flexible energy usage. The combustion process releases the energy stored in iron powder while the solid product, i.e., iron oxide can be easily collected and then reduced to metallic iron, enforcing a recyclable iron fuel cycle (Fig.1). We investigate the use of electrochemical technique for iron regeneration in the context of the iron fuel cycle [1-4]. The laboratory-scale experiments with parallel plate electrolyzer using aqueous NaOH (50%wt, 18 M) suspended with micron-sized Fe2O3 (hematite) powder are conducted in the present work. We study the electrochemical performance and deposition behavior of the iron, exploring different parameters such as current density, iron oxide concentration, temperature, NaOH concentration, and powder size, with the aim of achieving optimal Faradaic efficiency. A high Faradaic efficiency (>90%) and high iron purity cathodic deposition have been achieved in relatively low electrical energy consumption (less than 6 kWh/kg). The metallic iron is deposited in the form of unique dendritic structures on the cathode. (Fig. 2). The dendrites are located primarily on the side and edge of the cathode, indicating a diffusion-controlled mechanism. This structure makes it easy for direct harvest of the iron powder. A new reactor design with a rotating disc as a cathode is proposed to realize continuous electrolytic iron powder production [4]. The obtained results open new perspectives for the completion of the iron fuel cycle, by enabling a sustainable regeneration of iron.References:[1] N.van Graefschepe, A.I. Majid, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. NPS 17 Delft.[2] A.I. Majid, N.van Graefschepe, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. 32nd ISE Topical Meeting.[3] A.I. Majid, N.van Graefschepe, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. In preparation.[4] A.I. Majid, Y. Tang, G. Finotello, J.van der Schaaf, N.G. Deen. 2022. US Provisional Patent, 63/363,627<br/
Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure
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Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure
by Giulia Di Iorio,Laura Paglia *ORCID,Giulia PedrizzettiORCID,Virgilio GenovaORCID,Francesco MarraORCID,Cecilia BartuliORCID andGiovanni PulciORCID
INSTM Reference Laboratory for Materials and Surface Engineering, Sapienza University of Rome, Eudossiana 18, 00184 Rome, Italy
*
Author to whom correspondence should be addressed.
Coatings 2023, 13(9), 1602; https://doi.org/10.3390/coatings13091602
Original submission received: 10 August 2023 / Revised: 31 August 2023 / Accepted: 11 September 2023 / Published: 13 September 2023
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Abstract
SiC/SiC ceramic matrix composites (SiCf/SiC CMCs) are regarded as the new materials for the hot-section components of aircraft gas turbine engines, since they have one-third of the density of metallic superalloys, a higher temperature capability, good mechanical strength, and excellent thermal shock resistance. However, high-temperature water-vapor-rich combustion gases can induce severe surface recession phenomena in SiC/SiC leading to component failure. For this reason, it is necessary to design protective coatings, i.e., environmental barrier coatings (EBCs), able to protect the SiC/SiC surface in combustion environments. In the present work, ytterbium monosilicate (Yb2SiO5), stable when exposed to water vapor at high temperatures, and ytterbium disilicate (Yb2Si2O7), characterized by a thermal expansion coefficient closer to that of the substrate, were selected for a multilayer EBC system. EBCs were processed using the atmospheric plasma spray (APS) technique. A set of deposition parameters were tested, varying the power of the torch, and the composition and microstructure of the deposited coatings were studied in terms of porosity, crack density, and post-deposition phase retention by performing SEM, EDS, and XRD analysis. The results allow for the definition of the influence of deposition parameters on the final properties of multilayer EBC coatings
Correction to: Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review
No full textThe second author name was incorrectly published as Giula Maria Smylie. The correct name is Giulia Marie Smylie. The original article has been corrected
Scrivere senza anestesia. La chiarezza di Giulia Niccolai
No full textIl saggio colloca storicamente la narratrice e poetessa Giulia Niccolai nel canone del Novecento letterario italiano discutendone poetica e cifre stilistiche. L'ampia analisi proposta tocca tutte le opere dell'autrice evidenziandone i legami intertestuali, anche tra poesia e narrativa, e i progressivi sviluppi in un arco cronologico esteso, tra anni Sessanta e primi anni Duemila. Lo studio coglie anche l'importanza dei riferimenti alle arti visive, in particolare alla fotografia, che Giulia Niccolai ha praticato in prima persona negli anni della Neoavanguardia, e alla pittura americana.The essay places the narrator and poet Giulia Niccolai in the canonical twentieth century Italian literary discussing her poetics and stylistic figures. The wide analysis proposed touches all the works of the author highlighting the intertextual links, also between poetry and narrative, and the progressive developments in an extended chronological period, between the Sixties and early Twenties. The study also captures the importance of references to the visual arts, especially photography, which Giulia Niccolai has practiced in the years of the Neo-avant-garde, and to American painting
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L'afrofuturismo tra Stati Uniti e Italia. Dalla memoria storica ai viaggi intergalattici per re-immaginare futuri postumani
No full textIn this article the author explores the cultural movement called Afrofuturism, tracing its origins, features, simbology, and its historical and political meanings. Starting from the (supposed) discoursive gap between African and African American people on one side and technology and science fiction on the other, this paradigm addresses themes related to the intersection of African Diaspora and African cultures with technology and science fiction, with the aim to recover the history of slavery and racism through the projections into alternative space-time contexts. In particular, the author explores the feminist afrofuturism perspective in order to examine the specific oppression and cultural production of African and African American women. In doing so, the author analyzes the development of afrofuturism in Italy, focusing on the work of the singer and beatmaker Karima 2G
BDC-Decomposition for global influence analysis
No full textIn biochemical networks, the steady-state input-output influence is the sign of the output steady-state variation due to a persistent positive input perturbation; if the sign does not depend on the value of the strictly positive system parameters, the influence is structural. As recently shown for small perturbations, when the linearized system approximation is valid, steady-state input-output influences can be structurally assessed, for biochemical networks with m unknown parameters, by means of a vertex algorithm with complexity 2m. This letter shows that the structural input-output influence of a biochemical network is a global property, which does not require any small-perturbation assumption. It also shows that, using a new algorithm, the complexity can be reduced down to 2m-n , where n is the system order, thus drastically reducing the computation time. Finally, when the uncertain parameters belong to known intervals, non-conservative bounds are given for the steady-state ratio between output and input, allowing for sensitivity analysis.Accepted Author ManuscriptTeam Tamas Keviczk
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