87,951 research outputs found

    Response to “Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanism”

    No full text
    Response to “Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanism

    Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanism

    No full text
    Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanis

    Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanism

    No full text
    Particle Size Is a Primary Determinant for Sigmoidal Kinetics of Nanoparticle Formation: A “Disproof” of the Finke–Watzky (F-W) Nanoparticle Nucleation and Growth Mechanis

    Asynchronous, parallel on-line classification of P300 and ERD for an efficient hybrid BCI

    No full text
    Riechmann H, Hachmeister N, Ritter H, Finke A. Asynchronous, parallel on-line classification of P300 and ERD for an efficient hybrid BCI. In: Neural Engineering (NER), 2011 5th International IEEE/EMBS Conference on. IEEE; 2011: 412-415

    Relativistic jets in narrow-line Seyfert 1 galaxies. New discoveries and open questions

    No full text
    Before the launch of the Fermi satellite only two classes of AGNs were known to produce relativistic jets and thus emit up to the γ-ray energy range: blazars and radio galaxies, both hosted in giant elliptical galaxies. The first four years of observations by the Large Area Telescope on board Fermi confirmed that these two are the most numerous classes of identified sources in the extragalactic γ-ray sky, but the discovery of γ-ray emission from 5 radio-loud narrow-line Seyfert 1 galaxies revealed the presence of a possible emerging third class of AGNs with relativistic jets. Considering that narrow-line Seyfert 1 galaxies seem to be typically hosted in spiral galaxy, this finding poses intriguing questions about the nature of these objects, the onset of production of relativistic jets, and the cosmological evolution of radio-loud AGN. Here, we discuss the radio-to-γ-rays properties of the γ-ray emitting narrow-line Seyfert 1 galaxies, also in comparison with the blazar scenario

    Fitting Yeast and Mammalian Prion Aggregation Kinetic Data with the Finke−Watzky Two-Step Model of Nucleation and Autocatalytic Growth

    No full text
    Recently, we reported 14 amyloid protein aggregation kinetic data sets that were fit using the “Ockham’s razor”/minimalistic Finke−Watzky (F−W) two-step model of slow nucleation (A → B, rate constant k1) and fast autocatalytic growth (A + B → 2B, rate constant k2), yielding quantitative (average) rate constants for nucleation (k1) and growth (k2), where A is the monomeric protein and B is the polymeric protein [Morris, A. M., et al. (2008) Biochemistry 47, 2413−2427]. Herein, we apply the F−W model to 27 representative prion aggregation kinetic data sets obtained from the literature. Each prion data set was successfully fit with the F−W model, including three different yeast prion proteins (Sup35p, Ure2p, and Rnq1p) as well as mouse and human prions. These fits yield the first quantitative rate constants for the steps of nucleation and growth in prion aggregation. Examination of a Sup35p system shows that the same rate constants are obtained for nucleation and for growth within experimental error, regardless of which of six physical methods was used, a unique set of important control experiments in the protein aggregation literature. Also provided herein are analyses of several factors influencing the aggregation of prions such as glutamine/asparagine rich regions and the number of oligopeptide repeats in the prion domain. Where possible, verification or refutation of previous correlations to glutamine/asparagine regions, or the number of repeat sequences, in literature aggregation kinetics is given in light of the quantitative rate constants obtained herein for nucleation and growth during prion aggregation. The F−W model is then contrasted to four literature mechanisms that address the molecular picture of prion transmission and propagation. Key limitations of the F−W model are listed to prevent overinterpretation of the data being analyzed, limitations that derive ultimately from the model’s simplicity. Finally, possible avenues of future research are suggested

    Variations on the Author

    No full text
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Visuelle Aufmerksamkeit und Dyslexie. Parameterbasierte Untersuchung von gestörten und intakten Komponenten visueller Aufmerksamkeit.

    No full text
    Egetemeir J, Finke K, Stenneken P. Visuelle Aufmerksamkeit und Dyslexie. Parameterbasierte Untersuchung von gestörten und intakten Komponenten visueller Aufmerksamkeit. In: Petermann F, Koglin U, eds. 47. Kongress der Deutschen Gesellschaft für Psychologie 26. bis 30. September 2010. Abstracts. Lengerich: Pabst; 2010: 135

    Le R. P. Ewald Miller, O. F. M. Das Konzil von Vienne (1311-1312). Seine Quellen und seine Geschichte. Münster, in Westfalen, Aschendorffsche Verlagsbuchhandlung, 1934. (Vorreformationsgeschichtliche Forschungen herausgegeben von Heinrich Finke, XII.)

    No full text
    Tessier Georges. Le R. P. Ewald Miller, O. F. M. Das Konzil von Vienne (1311-1312). Seine Quellen und seine Geschichte. Münster, in Westfalen, Aschendorffsche Verlagsbuchhandlung, 1934. (Vorreformationsgeschichtliche Forschungen herausgegeben von Heinrich Finke, XII.). In: Bibliothèque de l'école des chartes. 1934, tome 95. pp. 367-371

    [Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]

    No full text
    Newspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.
    corecore