9,755 research outputs found
Charlie May Simon materials
No full textThis collection contains materials relating to Arkansas author Charlie May Simon
sj-docx-1-jic-10.1177_08850666231192371 - Supplemental material for Accuracy of International Classification of Disease Coding Methods to Estimate Sepsis Epidemiology: A Scoping Review
No full textSupplemental material, sj-docx-1-jic-10.1177_08850666231192371 for Accuracy of International Classification of Disease Coding Methods to Estimate Sepsis Epidemiology: A Scoping Review by Ashwani Kumar, Naomi Hammond, Sarah Grattan, Simon Finfer and Anthony Delaney in Journal of Intensive Care Medicine</p
Managing Patients Who Refuse Blood Transfusions: An Ethical Dilemma
No full textPatients who refuse blood transfusions after severe blood loss have a
poor prognosis but survival is possible. Below Simon Finfer and colleagues
describe how they managed two patients who presented after a car crash. We
asked an ethical expert, a former pathologist who is a Jehovah's Witness, and
a lawyer to comment on the issues that these cases raised
Simon Nyakot
No full textabstract: Simon Nyakot left his village when he was six years old.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 27Region: LakeThis picture and bio was donated to the Lost Boys Found project from The Arizona Lost Boys Cente
Pulmonary mechanical dysfunction in the critically ill
No full textModern ventilators employed in intensive care units (ICUs) display in real time and breath by breath flow (V̇), volume (V), and pressure (Paw) curves, both as a function of time and as a loop. Data obtained from curve analysis can help the physician to understand the interactions between the patient and the ventilator. The right interpretation of information provided from modern ventilators allows real time monitoring of the actual needs of the patient, ensuring a custom ventilatory support and reducing the risk of complications that can increase the mortality and prolong the ICU length of stay. In patients undergoing mechanical ventilation, measurements of respiratory mechanics can be performed at the bedside in dynamic (no flow interruption) or static (occlusion techniques) conditions. From these, it’s also possible to derive the values of pulmonary compliance and airway resistance
Cahiers Saint-Simon
No full texthttps://www.persee.fr/renderCollectionCover/simon.pngThe Société Saint-Simon was founded in 1972 in order to promote studies about the Duke of Saint-Simon (1675-1755), namely about the work, life, and thinking of the Mémoires’s author. Each year it issues a Cahier Saint-Simon. It contains the Acts of the annual Journée d’étude in Versailles, but also Notes and Documents, News of the Society and Book reviews.Fondée en 1972, la Société Saint-Simon a pour but de développer les études concernant l'oeuvre, la personne et la pensée du duc de Saint-Simon (1675-1755), l’auteur des Mémoires. Chaque année, paraît un numéro de Cahiers Saint-Simon contenant les actes de la journée annuelle de Versailles, ainsi que des Mélanges, des Notes et Documents et une Chronique bibliographique détaillée
Cahiers Saint-Simon
No full texthttps://www.persee.fr/renderCollectionCover/simon.pngThe Société Saint-Simon was founded in 1972 in order to promote studies about the Duke of Saint-Simon (1675-1755), namely about the work, life, and thinking of the Mémoires’s author. Each year it issues a Cahier Saint-Simon. It contains the Acts of the annual Journée d’étude in Versailles, but also Notes and Documents, News of the Society and Book reviews.Fondée en 1972, la Société Saint-Simon a pour but de développer les études concernant l'oeuvre, la personne et la pensée du duc de Saint-Simon (1675-1755), l’auteur des Mémoires. Chaque année, paraît un numéro de Cahiers Saint-Simon contenant les actes de la journée annuelle de Versailles, ainsi que des Mélanges, des Notes et Documents et une Chronique bibliographique détaillée
Management of tricyclic antidepressant poisoning
No full textAlthough a number of more recent substances with fewer side effects have become available for the treatment of depression, tricyclic antidepressants (TCA) are still commonly used. In addition, they are used for the treatment of neuropathic pain. The common basic mechanism of action is inhibition of reuptake of different neuromediators at the presynaptic terminal in both the central nervous system (CNS) and peripheral tissues, with the subsequent prolongation of their effect on the post-synaptic membrane. The earliest drug of this class was imipramine. Despite a phenothiazine-like structure it was not effective for the treatment of schizophrenia; quite unexpectedly, it improved depressive symptoms. Consequently, these substances and the derived TCAs became the first line of treatment for depression until the development of the selective serotonin reuptake inhibitors (SSRI). Although all TCAs share the same mechanisms of action, there are some differences in terms of the mediator involved. Whereas imipramine and some of its derivates, including amitriptyline and doxepin, block the reuptake of noradrenaline and serotonin at the presynaptic terminals, clomipramine has a more selective action on serotonin. After oral administration, TCAs are promptly absorbed and achieve peak blood concentrations in 2–6 hours; their absorption is reduced by antacids and drugs with anticholinergic effects. Being highly lipophilic, TCAs are rapidly taken up by the CNS. They are metabolized in the liver through oxidation and glucoronization. Although they undergo a relevant enterohepatic circulation, they are primarily eliminated through the kidney, with a half-life of 12–24 hours depending on the specific drug
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