241 research outputs found

    ENDOMETRIOSIS OF THE ABDOMINAL WALL, TWO OBSERVATIONS AND LITERATURE REVIEW

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    Ouakasse Samira*, Erhaymini Khalil, Jeraf Narjiss, Aicha Driouech, Adib Filali, Mohammed Hassan Alami and Rachid Beza

    Samira Bellil: Dans l'enfer des tournantes - commented translation extended by analysis of translation complexities and reception of literature of the "beurs"

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    This master's thesis consists of a Czech language translation and commentary for selected chapters of Dans l'enfer des tournantes, an autobiography by Samira Bellil, a French author of Algerian descent. The commentary is divided into two parts: a presentation of literature written by French authors of Maghrebi descent, the so-called beurs, the language they use in literature and reception of their works; and an analysis of the source text and its reception, the problems encountered during the process of translation and their solutions as well as the chosen translation method. Key words: Samira Bellil, autobiography, beurs, translation, translation analysis, translation method, translation problem, translation shift, suburbs of Pari

    Social media and the Arab Spring

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    In late of 2010 and during 2011, the Arab countries saw a series of large scale political uprisings. Facebook, Twitter, YouTube, and other forms of social media have played a major role in the planning, acceleration, and even the preparation of some of the uprisings and revolutions that too place in the Middle East at this time. Social media was employed effectively to awaken the Arab people and to mobilize them to fight against repressive regimes in their drive for greater freedom and independence. This paper will discuss the cause of the uprisings. In addition, the role of social media in the Middle East before the revolutions and the impact it had on the uprisings and revolutions known as the Arab Springs will be examined.M.A.L.S.Includes bibliographical referencesby Samira F. Hassa

    Development and study of the efficacy of an innovative hospital preparation for the treatment of chronic articular diseases

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    Les synoviocytes jouent un rôle crucial dans la pathogénèse des maladies articulaires chroniques, et particulièrement dans la phase de destruction ostéoarticulaire en devenant résistants à l’apoptose. Une première étude a mise en évidence une efficacité antiproliférative du cadmium minéral sur ces synoviocytes. Une preuve de concept d’un nouveau produit thérapeutique intra-articulaire à base de cadmium a été élaborée. Cette préparation pharmaceutique innovante, développée pour éviter la dissémination du cadmium minéral dans l’organisme, contenait des nanoparticules à base de cadmium, administrable sous forme liquide à température ambiante et se gélifiait à la température corporelle, en formant des micelles contenant des nanoparticules, ne traversant ainsi pas la cavité synoviale. Initialement, la reproductibilité de l’effet antiprolifératif du cadmium entre la forme minérale et les nanoparticules a été vérifiée dans un modèle in vitro de synoviocytes humains atteints de polyarthrites rhumatoïdes. Une captation différente des nanoparticules selon l’environnement inflammatoire ou pathologique des synoviocytes a été ensuite expliquée par la modification accrue de leurs morphologies. Similairement, l’effet de l’inflammation sur les propriétés physiques des vésicules, sécrétées par les synoviocytes, ont consolidé le choix des caractéristiques de la formulation. Les essais sur des modèles d’arthrite chez le rat ont permis de démontrer l’efficacité de cette nouvelle préparation originale, facilement injectable en intra-articulaire, en réduisant les scores cliniques avec une unique injection. Cette thérapie locale peut être une technique rapide et réalisable en ambulatoireSynoviocytes play a crucial role in the pathogenesis of chronic joint diseases, particularly in the osteoarticular destruction phase by becoming resistant to apoptosis. A first study has demonstrated an antiproliferative efficacy of cadmium mineral on these synoviocytes. A proof of concept of a new intra-articular cadmium-based therapeutic product has been developed. This innovative pharmaceutical preparation, developed to prevent the spread of mineral cadmium in the body, contained cadmium-based nanoparticles, which can be administered in liquid form at room temperature and gelled at body temperature, forming micelles containing nanoparticles, thus crossing the synovial cavity. Initially, the reproducibility of the antiproliferative effect of cadmium between the mineral form and the nanoparticles was verified in an in vitro model of human synoviocytes with rheumatoid arthritis. A different uptake of nanoparticles according to the inflammatory or pathological environment of synoviocytes was then explained by the massive modification of their morphologies. Similarly, the effect of inflammation on the physical properties of the vesicles, secreted by synoviocytes, consolidated the choice of the characteristics of the formulation.Tests on arthritis models in rats have demonstrated the effectiveness of this new original preparation, easily injectable intra-articular, reducing clinical scores with a single injection. This local therapy can be a quick technique and achievable in outpatien

    Interactions entre cellules et facteurs solubles dans les maladies articulaires chroniques : compréhension et ciblage thérapeutique

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    Synoviocytes play a crucial role in the pathogenesis of chronic joint diseases, particularly in the osteoarticular destruction phase by becoming resistant to apoptosis. A first study has demonstrated an antiproliferative efficacy of cadmium mineral on these synoviocytes. A proof of concept of a new intra-articular cadmium-based therapeutic product has been developed. This innovative pharmaceutical preparation, developed to prevent the spread of mineral cadmium in the body, contained cadmium-based nanoparticles, which can be administered in liquid form at room temperature and gelled at body temperature, forming micelles containing nanoparticles, thus crossing the synovial cavity. Initially, the reproducibility of the antiproliferative effect of cadmium between the mineral form and the nanoparticles was verified in an in vitro model of human synoviocytes with rheumatoid arthritis. A different uptake of nanoparticles according to the inflammatory or pathological environment of synoviocytes was then explained by the massive modification of their morphologies. Similarly, the effect of inflammation on the physical properties of the vesicles, secreted by synoviocytes, consolidated the choice of the characteristics of the formulation.Tests on arthritis models in rats have demonstrated the effectiveness of this new original preparation, easily injectable intra-articular, reducing clinical scores with a single injection. This local therapy can be a quick technique and achievable in outpatientLes synoviocytes jouent un rôle crucial dans la pathogénèse des maladies articulaires chroniques, et particulièrement dans la phase de destruction ostéoarticulaire en devenant résistants à l’apoptose. Une première étude a mise en évidence une efficacité antiproliférative du cadmium minéral sur ces synoviocytes. Une preuve de concept d’un nouveau produit thérapeutique intra-articulaire à base de cadmium a été élaborée. Cette préparation pharmaceutique innovante, développée pour éviter la dissémination du cadmium minéral dans l’organisme, contenait des nanoparticules à base de cadmium, administrable sous forme liquide à température ambiante et se gélifiait à la température corporelle, en formant des micelles contenant des nanoparticules, ne traversant ainsi pas la cavité synoviale. Initialement, la reproductibilité de l’effet antiprolifératif du cadmium entre la forme minérale et les nanoparticules a été vérifiée dans un modèle in vitro de synoviocytes humains atteints de polyarthrites rhumatoïdes. Une captation différente des nanoparticules selon l’environnement inflammatoire ou pathologique des synoviocytes a été ensuite expliquée par la modification accrue de leurs morphologies. Similairement, l’effet de l’inflammation sur les propriétés physiques des vésicules, sécrétées par les synoviocytes, ont consolidé le choix des caractéristiques de la formulation. Les essais sur des modèles d’arthrite chez le rat ont permis de démontrer l’efficacité de cette nouvelle préparation originale, facilement injectable en intra-articulaire, en réduisant les scores cliniques avec une unique injection. Cette thérapie locale peut être une technique rapide et réalisable en ambulatoir

    The Poetics of Textual Thresholds in Ahcene El-Kharrat’s Collections of Poetry

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    Abstract: The aim of this study is to analyze the poetics of textual thresholds in the poetry of Ahcene El-Kharrat (1989-2019), to query their various dimensions, connotations and artistic features, based on the assumption that contemporary poetic text is no longer just a set of poems nicely written and collected in a book, but rather a mosaic of written texts, para (meta) texts, and thresholds related to their hypertext. The thresholds’ role is vital. Its importance cannot be ignored while formulating the general poetic context of the poem. The latter cannot reach completeness without its textual thresholds that opens up new poetic and artistic perspectives. We will shed light, in this analytical and intertextual research, on the thresholds of the poems in the collections of the Algerian poet Ahcene El-Kharrat entitled: Nabdh-al-faji’a (Pulse of Bereavement), Basar Al-Turab (Sight of the earth) and Shatah Al-darawishes (the Dervishes’ imagination). Keywords: Textual Thresholds; Paratext; Connotation; Author; Poetic

    Electron–hole superfluidity in strained Si/Ge type II heterojunctions

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    Excitons are promising candidates for generating superfluidity and Bose–Einstein condensation (BEC) in solid-state devices, but an enabling material platform with in-built band structure advantages and scaling compatibility with industrial semiconductor technology is lacking. Here we predict that spatially indirect excitons in a lattice-matched strained Si/Ge bilayer embedded into a germanium-rich SiGe crystal would lead to observable mass-imbalanced electron–hole superfluidity and BEC. Holes would be confined in a compressively strained Ge quantum well and electrons in a lattice-matched tensile strained Si quantum well. We envision a device architecture that does not require an insulating barrier at the Si/Ge interface, since this interface offers a type II band alignment. Thus the electrons and holes can be kept very close but strictly separate, strengthening the electron–hole pairing attraction while preventing fast electron–hole recombination. The band alignment also allows a one-step procedure for making independent contacts to the electron and hole layers, overcoming a significant obstacle to device fabrication. We predict superfluidity at experimentally accessible temperatures of a few Kelvin and carrier densities up to ~6 × 1010 cm−2, while the large imbalance of the electron and hole effective masses can lead to exotic superfluid phases.QCD/Scappucci La
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