2,278 research outputs found
Domain Names in Turkey
No full textTurkey faces both unique and common domain name regulatory issues. In this paper, the author focuses on the challenges ahead for Turkey, with especial focus on the regulation of IDNs
Plagiarism: concepts and contexts
No full textAfter outlining the key difficulties in modern literature on academic plaigarism, the author suggests that these may be resolved by a new model of plaigarism (whilst noting that this new model does raise additional uncertainties, e.g. as to the status of 'self plagiarism') that she has developed
Dictionary of Acoustics
No full textThe science and technology of acoustics embraces an unusually wide range of disciplines, from aircraft noise reduction to ultrasonics in medicine, from psychoacoustics to signal processing. The student of acoustics has to become familiar with a corresponding range of specialist terms in order to communicate with others and to understand the literature. Here, in one informative dictionary, for the first time, are listed accurate and helpful definitions to provide the student - or the specialist from another discipline - with a point of entry into the world of acoustics. The dictionary's 2,800 entries cover most of the essential concepts and terminology that the practicing acoustician needs to understand, outside the subfields of music and speech communication. The author has drawn on experience gained during a long career spent mostly at Southampton University's multidisciplinary Institute of Sound and Vibration Research, supplemented by the expertise and perspective of a team of subject specialists
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
Measuring Red Blood Cell Aggregation Forces Using Double Optical Tweezers
No full textClassic immunohematology approaches, based on agglutination techniques, have been used in manual and automated immunohematology laboratory routines. Red blood cell (RBC) agglutination depends on intermolecular attractive forces (hydrophobic bonds, Van der Walls, electrostatic forces and hydrogen bonds) and repulsive interactions (zeta potential). The aim of this study was to measure the force involved in RBC aggregation using double optical tweezers, in normal serum, in the presence of erythrocyte antibodies and associated to agglutination potentiator solutions (Dextran, low ionic strength solution [LISS] and enzymes). The optical tweezers consisted of a neodymium:yattrium aluminium garnet (Nd:YAG) laser beam focused through a microscope equipped with a minicam, which registered the trapped cell image in a computer where they could be analyzed using a software. For measuring RBC aggregation, a silica bead attached to RBCs was trapped and the force needed to slide one RBC over the other, as a function of the velocities, was determined. The median of the RBC aggregation force measured in normal serum (control) was 1 × 10-3 (0.1-2.5) poise.cm. The samples analyzed with anti-D showed 2 × 10-3 (1.0-4.0) poise.cm (p < 0.001). RBC diluted in potentiator solutions (Dextran 0.15%, Bromelain and LISS) in the absence of erythrocyte antibodies, did not present agglutination. High adherence was observed when RBCs were treated with papain. Results are in agreement with the imunohematological routine, in which non-specific results are not observed when using LISS, Dextran and Bromelain. Nevertheless, false positive results are frequently observed in manual and automated microplate analyzer using papain enzyme. The methodology proposed is simple and could provide specific information with the possibility of meansuration regarding RBC interaction. © 2013 Informa Healthcare.733262264Acronym; Sponsor: UM; National Science and Technology Development AgencyEylar, E.H., Madoff, M.A., Brody, O.V., Oncley, J.L., The contribution of sialic acid to the surface charge of the erythrocyte (1962) JBiol Chem, 237, pp. 1992-2000Jaime, J.C., Immune-medicated agglutination of cytoskeletonfree RBC microvesicles (2000) Transfusion, 40, pp. 566-570Van Oss, C.J., Absolon, D.R., Zeta potential van der walls forces and hemagglutination (1983) Vox Sang, 44, pp. 183-190Pollack, W., Hager, H.J., Reckel, R., Toren, D.A., Singher, H.O., Astudy of the forces involved in the second stage of hemagglutination (1965) Transfusion, 5, pp. 158-183Storry, J.R., Areview: Modifi cation of the red blood cell membrane and its application in blood group serology (2000) Immunohematology, 16, pp. 101-104Fernandes, H.P., Cesar, C.L., Barjas-Castro, M.L., Electrical properties of the red blood cell membrane and immunohematological investigation (2011) Rev Bras Hematol Hemoter, 33, pp. 297-301Neu, B., Wemby, R., Meiselman, H.J., Effects of Dextran molecular weight on red blood cell aggregation (2008) Biophys J, 95, pp. 3059-3065Silva, D.C., Jovino, C.N., Silva, C.A., Fernandes, H.P., Filho, M.M., Lucena, S.C., Costa, A.M., Fontes, A., Optical tweezers as a new biomedical tool to measure zeta potential of stored red blood cells (2012) PLoS One, 7, pp. e317781-e317786Brandão, M.M., Fontes, A., Barjas-Castro, M.L., Barbosa, L.C., Costa, F.F., Cesar, C.L., Saad, S.T., Optical tweezers for measuring red blood cell elasticity: Application to the study of drug response in sickle cell disease (2003) Eur J Haematol, 70, pp. 207-211Fontes, A., Fernandes, H.P., Thomaz, A.A., Barbosa, L.C., Barjas-Castro, M.L., César, C.L., Measuring electrical and mechanical properties of red blood cells with double optical tweezers (2008) J Biomed Opt, 13, pp. 0140011-0140016Fontes, A., Fernandes, H.P., Thomaz, A.A., Barbosa, L.C., Barja-Castro, M.L., Cesar, C.L., Studying red blood cell agglutination by measuring electrical and mechanical properties with a double optical tweezers (2007) European Conferences on Biomedical Optics, , Munich. Biophotonics 2007 : Opt Life Sci 200766330R.1-10(2011) American Association Of Blood Banks (AABB, , Technical Manual 17th Edition. Bethesda MA USA: AABBHochmuth, R.M., Worthy, P.R., Evans, E.A., Red cell extensional recovery and the determination of membrane viscosity (1979) J Biophys, 26, pp. 101-11
Modelling of turbulent jets and wall layers: extensions of Lighthill's acoustic analogy with application to computational aeroacoustics
No full textTwo extensions to Lighthill’s aeroacoustic analogy are presented. First, equivalent sources due to initial conditions are derived that supplement those due to boundary conditions, as given by Ffowcs Williams & Hawkings. The resulting exact inhomogeneous wave equation is then reformulated with pressure rather than density as the wave variable, and the right-hand side is rearranged using the energy equation with no additional assumptions. Applications to computational aeroacoustics are discussed, and illustrated with examples based on 2D and 3D simulations
Coauthor prediction for junior researchers
No full textResearch collaboration can bring in different perspectives and generate more productive results. However, finding an appropriate collaborator can be difficult due to the lacking of sufficient information. Link prediction is a related technique for collaborator discovery; but its focus has been mostly on the core authors who have relatively more publications. We argue that junior researchers actually need more help in finding collaborators. Thus, in this paper, we focus on coauthor prediction for junior researchers. Most of the previous works on coauthor prediction considered global network feature and local network feature separately, or tried to combine local network feature and content feature. But we found a significant improvement by simply combing local network feature and global network feature. We further developed a regularization based approach to incorporate multiple features simultaneously. Experimental results demonstrated that this approach outperformed the simple linear combination of multiple features. We further showed that content features, which were proved to be useful in link prediction, can be easily integrated into our regularization approach. © 2013 Springer-Verlag
Optimised search heuristic combining valid inequalities and tabu search
No full textThis paper presents an Optimised Search Heuristic that combines a tabu search method with the verification of violated valid inequalities. The solution delivered by the tabu search is partially destroyed by a randomised greedy procedure, and then the valid inequalities are used to guide the reconstruction of a complete solution. An application of the new method to the Job-Shop Scheduling problem is presented.Optimised Search Heuristic, Tabu Search, GRASP, Valid Inequalities, Job Shop Scheduling
Studying Red Blood Cell Agglutination By Measuring Membrane Viscosity With Optical Tweezers
No full textThe red blood cell (RBC) viscoelastic membrane contains proteins and glycoproteins embedded in a fluid lipid bilayer that are responsible for cell agglutination. Manipulating RBCs rouleaux with a double optical tweezers, we observed that the cells slide easily one over the others but are strongly connected by their edges. An explanation for this behavior could be the fact that when the cells slide one over the others, proteins are dragged through the membrane. It confers to the movement a viscous characteristic that is dependent of the velocity between the RBCs and justifies why is so easy to slide them apart. Therefore, in a first step of this work, by measuring the force as a function of the relative velocity between two cells, we confirmed this assumption and used this viscous characteristic of the RBC rouleaux to determine the apparent membrane viscosity of the cell. As this behavior is related to the proteins interactions, we can use the apparent membrane viscosity to obtain a better understanding about cell agglutination. Methods related to cell agglutination induced by antigen-antibody interactions are the basis of most of tests used in transfusion centers. Then, in a second step of this work, we measured the apparent membrane viscosity using antibodies. We observed that this methodology is sensitive to different kinds of bindings between RBCs. Better comprehension of the forces and bindings between RBCs could improve the sensibility and specificity of the hemagglutination reactions and also guides the development of new potentiator substances.6644Fontes, A., Fernandes, H.P., Barjas-Castro, M.L., Thomaz, A.A., Pozzo, L., Barbosa, L.C., Cesar, C.L., Red blood cell membrane viscoelasticity, agglutination and zeta potential measurements with double optical tweezers (2006) Proceedings of SPIE, 6088, pp. 296-305Eylar, E.H., Madoff, M.A., Brody, O.V., Oncley, J.L., The contribution of sialic acid to the surface charge of the erythrocyte (1962) J. Biol. Chem, 237, pp. 1992-2000Pollack, W., Reckel, R.P., A reappraisal of the forces involved in Hemagglutination (1977) Int Archs Allergy Appl. Immun, 54, pp. 29-42Fontes, A., Giorgio, S., de Castro Jr., A.B., Neto, V.M., Pozzo, L.Y., Marques, G.P., Barbosa, L.C., Cesar, C.L., Determination of femto Newton forces and fluid viscosity using optical tweezers: Application to Leishmania amazonensis (2005) Proceedings of SPIE, 5699, pp. 419-425Saffman, P.G., Delbruck, M., Brownian motion in biological membranes (1975) Proc. Nat. Acad. Sci. USA, 72, pp. 3111-3113Dimova, R., Danov, K., Pouligny, B., Ivanov, I.B., Drag of a solid particle trapped in a thin film or at an interface: Influence of surface viscosity and elasticity (2000) J. Colloid and Interface Science, 226, pp. 35-4
[] to C.L. Thomas, 26 January 1850
No full texthttps://egrove.olemiss.edu/aldrichcorr_b/1214/thumbnail.jp
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