309 research outputs found
Getting the right balance in treatment of ductal carcinoma in situ (DCIS)
Get PDFAs a result of mammographic detection, ductal carcinoma in situ (DCIS) is an increasing problem in breast clinics. Both histopathology and molecular profiling can identify subtypes likely to progress to invasive disease, but there is no subgroup with a zero likelihood of subsequent invasion. In patients with low/intermediate grade DCIS, if breast irradiation is not being carried out after free margins have been achieved the patient should be aware of the risks of withholding and the benefits and morbidity of adjuvant radiotherapy. Either tamoxifen or an aromatase inhibitor may be of value in those with low/intermediate ER+ve disease if radiotherapy is being withheld. For those patients with extensive or multicentric DCIS, mastectomy is the appropriate treatment. This is best combined with sentinel node biopsy and all such cases should be offered immediate reconstruction.----------------------------Cite this article as:Fentiman IS. Getting the right balance in treatment of ductal carcinoma in situ (DCIS). Int J Cancer Ther Oncol 2013; 1(2):01029.DOI: http://dx.doi.org/10.14319/ijcto.0102.9
A necessary fiction: The ritualisation of stakeholder practices in New Zealand cinema
No full textThis thesis argues that stability of the concept ‘national cinema’ is located in the discursive positioning of individual films in such a way that they are connected to a national ‘common ground’, one which is ritually accessed via engagement with media such as cinema. This positioning, however, is not quantifiable and may not be identified as arising from any particular production practice, dimension of popularity, theme, style, characteristic of production personnel, and so on. By synthesising the work of several theorists and applying this synthesis to a selection of films, a framework of ideas (around the ritualised ‘flagging’ of the national via the expression of stakeholder interests) is applied to cinema in New Zealand. In particular, an ideoscape is ultimately mapped as a result of applying this framework of ideas. The normative assumptions of national cinema are examined in this way and found to be lacking despite the weight that the term ‘national cinema’ continues to have
192 - Ian Cook McLean
No full textCurrently, most in vitro experimental models of the intestine rely upon cell lines, and consequently, lack the diverse representation of cells present in vivo. Slices of intestine, removed from living organisms, offer a better representation of in vivo physiology. However, current techniques for maintaining intestinal tissue in vitro are not capable of recapitulating the in vivo environment.
This project utilizes 3D printing and microfluidic principles to design a device that delivers differential flows of media across the two surfaces of intestinal tissue. The device will enable the investigation of complex biological questions that previous models have been unable to address
Beauty for the Present: Mill, Arnold, Ruskin and Aesthetic Education
Get PDFThe present thesis examines the idea of aesthetic education of three eminent Victorians: John Stuart Mill, Matthew Arnold and John Ruskin. By focusing on the essence of what they meant with ‘the cultivation of the beautiful’ and, more importantly, the way their ideas of beauty informed their criticism of society, my study aims to contribute to our understanding of the idea of aesthetic education in the Victorian context and, further, to participate in a recent debate about the nature of beauty and aesthetic education.
Chapter One focuses on John Stuart Mill’s concept of ‘feeling’ in a series of essays. I will demonstrate how Mill’s idea of ‘aesthetic education’ was an ‘education of feelings,’ and moreover, how this idea was integrated into his literary criticism, his later critique of democratisation, his description of an ideal liberal society and even his own style of writing. Chapter Two contains a comparative study of Matthew Arnold and Friedrich Schiller. Through a rereading of Arnold, I will argue that his idea of aesthetic education is essentially Schillerian and that their resemblance consists primarily in their stress on the importance of aesthetic unity for modern life, which was becoming increasingly fragmentary and multitudinous. Chapter Three examines John Ruskin’s idea of aesthetic education and concentrates particularly on the cultivation of perception. Perception, as I shall show, was pivotal in Ruskin’s idea of aesthetic education. Just as what happened in Mill and Arnold, the emphasis on the education of seeing continued from his early writings well into his art and social criticisms. It not only differentiated him from his fellow art critics; the conviction that people should perceive with a pure heart also enabled him to link observation of artistic details with moral criticism of contemporary society and, thereby, to turn the cultivation of the beautiful into a moral-aesthetic experience
Selling fashion: realizing the research potential of the House of Fraser archive, University of Glasgow Archive Services
Get PDFThe House of Fraser archive is a rich resource for the study of the development of fashion retailing in Britain since the mid-nineteenth century. It is, however, underexploited by textile, fashion and retail historians. During the summer of 2009, the University of Glasgow archive services will complete an Arts and Humanities Research Council-funded project which seeks to improve the accessibility of the Archive. Adopting a progressive approach to archival description, the project is developing an innovative online catalogue, providing fuller access to information about the Archive and the resources contained within it
Too many copies: confusion between duplication and versioning
No full textPresentation at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014General Track, 24x7 PresentationsThe session was recorded and is available for watching (this presentation starts at 0:09:19)Duplication is a fundamental part of how the internet works. In a cloud environment, resources are expected to be available, always. Duplication provides the solution. Several copies scattered around the web ensure that at least one of them is accessible at any given time. Duplication is a good thing.
But how do repositories deal with duplication? Should a repository hold more than one copy of a deposit? Open Access mandates encourage this duplication. Institutions request the author to deposit his copy with the institutional repository. Funders require a copy to be deposited in subject repositories. Obviously, publishers advertise their copy. CRIS receive deposits from aggregations and subject repositories. Aggregations collect deposits from institutional and subject repositories. An institutional repository may receive multiple copies of a research publication from different sources. Are these copies identical? How to differentiate them? Which copy should be kept? Should more than one version of a deposit be kept?
Support for versioning is required in order to tag deposits and enable repository managers to select the appropriate copy. Quality of the metadata and annotation, provenance information and trust are important. A global approach that engages all systems and partners of the Repository Ecosystems is needed.Mewissen, Muriel (EDINA, The University of Edinburgh, United Kingdom)Stuart, Ian (EDINA, The University of Edinburgh, United Kingdom)Rees, Christine (EDINA, The University of Edinburgh, United Kingdom)Burnhill, Peter (EDINA, The University of Edinburgh, United Kingdom
From Stoke Mandeville to Stratford: A History of the Summer Paralympic Games
Get PDFAs Aristotle once said, “If you would understand anything, observe its beginning and its development.” When Dr Ian Brittain started researching the history of the Paralympic Games after beginning his PhD studies in 1999, it quickly became clear that there was no clear or comprehensive source of information about the Paralympic Games or Great Britain’s participation in the Games. This book is an attempt to document the history of the summer Paralympic Games and present it in one accessible and easy-to-read volume. From the outset, it should be made very clear that this book is not meant to be an academic text. It has always been the author’s intention that it should be a resource for anyone with an interest in the Paralympic Games, their history, or Great Britain’s participation in the Games. Through twelve years of research, the author has brought together all of the facts, figures, and interesting stories that have occurred in the development of the summer Games—from their roots at Stoke Mandeville Hospital in the United Kingdom to the global mega-event they have become today. This is the first publication to include images of posters, winner’s medals, and other artefacts connected with the Games—some of which have never been seen in print. Every endeavour has been made to include all relevant information, and this text serves as an ideal starting point from which future researchers and historians may begin. As we have noticed recently with the increased documentation of Olympic history, it is the author’s hope that this text will inspire others to contribute to a more complete history of the Paralympic Games. A more complete history may lead to a better understanding of the importance of the Paralympic Games and their impact upon the lives of people with disabilities
Tax Deducations, Consumption Distortions, and the Marginal Excess Burden of Taxation
Get PDFCertain types of expenditure�e.g. mortgage interest and medical insurance�receive favorable tax treatment and are effectively subsidized relative to other (non-tax-favored) expenditures. Labor taxes (e.g. income taxes) can therefore produce efficiency losses by distorting the allocation of consumption, in addition to distorting the labor market. Using evidence on the responsiveness of taxable income to changes in tax rates, a seminal study by Feldstein (1999) estimates that the marginal excess burden of taxation (MEB) could exceed unity, when the effects of tax deductions are taken into account. This is several times larger than in previous studies of the MEB that focus exclusively on labor market effects. This paper develops a "disaggregated" approach to estimating the MEB that decomposes welfare impacts in the market for labor and tax-favored consumption goods, and uses micro evidence on labor supply elasticities, the demand elasticity for mortgage interest, medical insurance, and so on. Based on Monte Carlo simulations, the author finds a 68 percent probability that the MEB lies between .31 and .48 for government transfer spending and between .21 and .35 for public goods. These estimates are below Feldstein's, but are still considerably higher (70 percent or more) than when we ignore tax deductions.
Treasures of the University : an examination of the identification, presentation and responses to artefacts of significance at the University of St Andrews, from 1410 to the mid-19th century; with an additional consideration of the development of the portrait collection to the early 21st century
No full textSince its foundation between 1410 and 1414 the University of St Andrews has acquired what can be considered to be ‘artefacts of significance’. This somewhat nebulous phrase is used to denote items that have, for a variety of reasons, been deemed to have some special import by the University, and have been displayed or otherwise presented in a context in which this status has been made apparent.
The types of artefacts in which particular meaning has been vested during the centuries under consideration include items of silver and gold (including the maces, sacramental vessels of the Collegiate Church of St Salvator, collegiate plate and relics of the Silver Arrow archery competition); church and college furnishings; artworks (particularly portraits); sculpture; and ethnographic specimens and other items described in University records as ‘curiosities’ held in the University Library from c. 1700-1838.
The identification of particular artefacts as significant for certain reasons in certain periods, and their presentation and display, may to some extent reflect the University's values, preoccupations and aspirations in these periods, and, to some degree, its identity. Consciously or subconsciously, the objects can be employed or operate as signifiers of meaning, representing or reflecting matters such as the status, authority and history of the University, its breadth of learning and its interest and influence in spheres from science, art and world cultures to national affairs.
This thesis provides a comprehensive examination of the growth and development of the University's holdings of 'artefacts of significance' from its foundation to the mid-19th century, and in some cases (especially portraits) beyond this date. It also offers insights into how the University viewed and presented these items and what this reveals about the University of St Andrews, its identity, which changed and developed as the living institution evolved, and the impressions that it wished to project
Public sector accounting reforms in the Indonesian post-Suharto era
No full textThe aim of the study is to understand the institutionalization process of an accrual accounting system in the Indonesian public sector. The data were drawn from three sources: (1) official documents (i.e. laws and government regulations) about the adoption and implementation of accrual accounting in the Indonesian public sector; (2) publicly available information about the social, economic and political developments leading to the process of the adoption; (3) interviews with 36 participants who have been involved in or have an understanding of the internalization of accrual accounting in the Indonesian public sector. Drawn from an integrated model of institutionalization (IMI) adapted from Dillard, Rigsby, and Goodman (2004), and Dambrin, Sponem, and Lambert (2007) inspired by New Institutional Sociology (NIS) this study was able to identify and discuss the features of the institutionalization process, at the national level and within one municipality used as a case study.
This study found that at the economic and political level and in the organizational field the new ideals which require the adoption of accrual accounting in the Indonesian public sector have been mobilized by the technocrats (economists and accountants) at the Ministry of Finance since the 1980s. This mobilization occurred when the country encountered a fiscal crisis. The study also identified that the desire to adopt accrual accounting may have been driven by the wish to follow a similar practice adopted in other countries. Nonetheless, a formal adoption of the accrual accounting system was only realized following the collapse of Suharto’s regime in 1998 through the issuance of Law 17 (2003) as new discourses and government accounting standards in 2005 as new techniques. In this municipal case, beyond the economic reasons, the move to formally adopt the accrual accounting system at the economic and political level after Suharto appeared to be part of the government’s response to the demand from the public and international financial authorities (the IMF and the World Bank).
At the organizational level, drawing from the experience of one municipal government, the internalization processes of the accounting system were primarily motivated by the presence of legal enforcement. This occurs because the political and economic affairs of local governments in Indonesia are regulated by the central government. Therefore, local governments effectively contribute to the domination of the central government in the mobilization process. Beyond this, the process and outcomes of the institutionalization of the accrual accounting system contradict the intended benefits, as expected in the Law 17 (2003), and the government accounting standards issued in 2005. In this case, the lack of skills and experience in using accrual accounting has increased accounting costs of the municipality and the officials within the municipality have yet to use the accrual-based accounting information for real decision making.
In addition, power and old habits of local actors (i.e. senior officials in a municipal government observed) relating to a corruption practice (bribery) surrounding the adoption have also produced an unintended outcome. In this vein, technical capacity, power, and old habits of local actors affect the extent to which a new accounting system could be internalized. An important insight that we can draw from this study is that the process and outcomes of this institutionalization are not only shaped by the pressures from external factors, but also by activities, processes and routines of actors within organizations.
One of the implications of the these findings for policy making is that Indonesian Central Goverment needs to be aware of the capacity of local governments in implementing policies and programs anfd provides approptriate incentives to achieve full uptake. A lack of competencies besides making successful implementation difficult, may exacerbate frustration fuelling active resistance. Further research could address the relationship between capability building and the proximity of educational institutions. The thesis indicates that successful implementation is limited. This encourages further research into the factors that impact implementation. The influence of culture such as a common practice of bribery should also be considered.
The public and academics are also reminded that the adoption of a business-style accounting system in the public sector can be costly and may act against its promoted purposes. The thesis also contributes to the public sector accounting literature by reducing the gap between what is known and unknown about governmental accounting practices in one of emerging economies in Asia, that has been rarely investigated
- …
