10,290 research outputs found

    Social trauma and the mu-opioid system in depression

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    The overarching thesis under investigation is that the endogenous opioid system plays a key role in depression subsequent to traumatic childhood social experiences. This is suggested by the fact that animal work indicates that mu-opioids robustly mediate separation-distress, and that early social stressors lead to long term dysregulation in key related circuitries and neuroanatomical structures

    Visiting author Dr. Arthur Schlesinger, Jr. at MU

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    Visiting author Dr. Arthur Schlesinger, Jr. at MU , b&w. Schlesinger wrote a book on disuniting America.https://mds.marshall.edu/parthenon_photo_morgue/1756/thumbnail.jp

    Visiting author Dr. Arthur Schlesinger, Jr. being interviewed at MU

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    Visiting author Dr. Arthur Schlesinger, Jr. being interviewed at MU , b&w. Schlesinger wrote a book on disuniting America.https://mds.marshall.edu/parthenon_photo_morgue/1757/thumbnail.jp

    The relationship between co-authorship, currency of references and author self-citations

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    This paper attempts to identify the relationship between co-authorship and the currency of the references and author self-citations in the key journals of environmental engineering. The results show that the self-citation rate of co-authored articles is higher than in single-authored articles. A statistically significant correlation is identified between the numbers of co-authors, the rate of author self-citing and the author self-cited; though it was a low correlation. The value of coefficient correlation between the number of co-authors and the author self-citing rate is slightly higher than that between the number of co-authors and the author self-cited rate, which indicates that the number of co-authors hold a stronger correlation with the self-citing rate than the self-cited rate. Meanwhile, self-citing references are found to be more up-to-date than references to others. The range of publication years of self-citing references is smaller than that of references to others, indicating that researchers tend to preferentially cite their own recent works. There is no significant difference in the latest references between self-citing references and the references to others. It might result from electronic journals that provide an easy access to the most current publications.補正完畢國外SSCIY紙本電子版HU

    Electron Crystallography Reveals Atomic Structures of Metal-Organic Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) Secondary Building Units

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    Nanoscale metal organic frameworks (nMOFs) have shown tremendous potential in cancer therapy and biomedical imaging. However, their small dimensions present a significant challenge in structure determination by single-crystal X-ray crystallography. We report here the structural determination of nMOFs by rotation electron diffraction (RED). Two isostructural Zr- and Hf-based nMOFs with linear biphenyldicarboxylate (BPDC) or bipyridinedicarboxylate (BPYDC) linkers are stable under intense electron beams to allow the collection of high-quality RED data, which reveal a MOF structure with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) secondary building units (SBUs). The nMOF structures differ significantly from their UiO bulk counterparts with M-6(mu(3)-O)(4)(mu(3)-OH)(4) SBUs and provide the foundation for clarifying the structures of a series of previously reported nMOFs with significant potential in cancer therapy and biological imaging. Our work clearly demonstrates the power of RED in determining nMOF structures and elucidating the formation mechanism of distinct nMOF morphologies.National Natural Science Foundation; Ministry of Science and Technology of the People's Republic of China [NSFC21671162, NSFC21471126, 2016YFA0200702]; National Thousand Talents Program of the People's Republic of China; 985 Program of Chemistry and Chemical Engineering Disciplines of Xiamen University; U.S. National Science Foundation [DMR-1308229]SCI(E)ARTICLE148128-81345

    Phase Diagram at Finite Chemical Potentials in the Nambu-Jona-Lasinio Model

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    We study the phase diagram of two flavor dense QCD at finite isospin and baryon chemical potentials in the framework of Nambu-Jona-Lasinio model. The system undergoes a crossover from a Bose-Einstein condensate of charged pions to a BCS superfluid with condensed quark-antiquark Cooper pairs when mu(I) increases at mu(B) = 0, and a nonzero baryon chemical potential serves as a mismatch between the pairing species. We observe a gapless pion condensation phase near the quadruple point (mu(I), mu(B)) = (m(pi), M-N-1.5m(pi)) where m(pi), M-N are the vacuum masses of pions and nucleons, respectively. At very large isospin chemical potential, mu(I) > 6.36m(pi), an inhomogeneous LOFF superfluid phase appears in a window of mu(B). Between the gapless and the LOFF phases, the pion superfluid phase and the normal quark matter phase are connected by a first order phase transition.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000302957500023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Physics, Atomic, Molecular & ChemicalCPCI-S(ISTP)

    Two Returns

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    Autorka analizuje Wiosnę w małym miasteczku (2002) Tiana Zhuangzhuanga jako reinterpretację wersji zrealizowanej przez Fei Mu w 1948 r. Ten ostatni film, odrzucony przez władze, pozostawał przez kilka dekad w zapomnieniu. W 2002 r. został ogłoszony najwybitniejszym chińskim filmem stulecia. Autorka upatruje różnic między filmami w fakcie, że Fei Mu realizował film naonczas współczesny, podczas gdy Tian zrobił film historyczny, dążąc do zachowania efektu dystansu. Obaj twórcy posługiwali się strategią „okrężnej drogi” oraz nawiązywali do podobnych założeń formalnych, integrując estetykę starego malarstwa chińskiego z pracą kamery.The author analyses the Springtime in a Small Town (2002) by Tian Zhuangzhuang as a reinterpretation of a version made by Fei Mu (Spring in a Small Town) in 1948. This latter film which was rejected by the authorities, remained hidden and forgotten for decades. In 2002 it was declared to be the best Chinese film of the century. The author explains the differences between the films by the fact that Fei Mu made a film that was contemporary to himself, while Tian made a historical film, aiming to maintain the effect of distance. Both artists used the “detour” strategy and relied on similar formal solutions, integrating the aesthetics of old Chinese painting with camera work

    Personality and attention bias in adults with a history of childhood trauma, and attenuating effects of mu-opioid agonist buprenorphine on attention bias

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    The current study compared personality characteristics and cognitive functioning (specifically, attentional bias) in a sample of adults who had experienced childhood trauma (the Trauma group) and a matched healthy control group. The study also examined the possible effects of the mu-opioid agonist buprenorphine on attentional bias in the Trauma group

    Mu-Beta event-related (de)synchronization and EEG classification of left-right foot dorsiflexion kinaesthetic motor imagery for BCI

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    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The left and right foot representation area is located within the interhemispheric fissure of the sensorimotor cortex and share spatial proximity. This makes it difficult to visualize the cortical lateralization of event-related (de)synchronization (ERD/ERS) during left and right foot motor imageries. The aim of this study is to investigate the possibility of using ERD/ERS in the mu, low beta, and high beta bandwidth, during left and right foot dorsiflexion kinaesthetic motor imageries (KMI), as unilateral control commands for a brain-computer interface (BCI). EEG was recorded from nine healthy participants during cue-based left-right foot dorsiflexion KMI tasks. The features were analysed for common average and bipolar references. With each reference, mu and beta band-power features were analysed using time-frequency (TF) maps, scalp topographies, and average time course for ERD/ERS. The cortical lateralization of ERD/ERS, during left and right foot KMI, was confirmed. Statistically significant features were classified using LDA, SVM, and KNN model, and evaluated using the area under ROC curves. An increase in high beta power following the end of KMI for both tasks was recorded, from right and left hemispheres, respectively, at the vertex. The single trial analysis and classification models resulted in high discrimination accuracies, i.e. maximum 83.4% for beta ERS, 79.1% for beta ERD, and 74.0% for mu ERD. With each model the features performed above the statistical chance level of 2-class discrimination for a BCI. Our findings indicate these features can evoke left-right differences in single EEG trials. This suggests that any BCI employing unilateral foot KMI can attain classification accuracy suitable for pra

    sj-pdf-1-imr-10.1177_03000605221133988 - Supplemental material for Lamotrigine induced priapism in children: case analysis and literature review

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    Supplemental material, sj-pdf-1-imr-10.1177_03000605221133988 for Lamotrigine induced priapism in children: case analysis and literature review by Jie Ge, Shan-Shan Cao, Xiao-Yu Cao, Meng Tang, Fei Mu, Yi Qiao, Yue Guan and Jing-Wen Wang in Journal of International Medical Research</p
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