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    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Impact on touch DNA of an alcohol-based hand sanitizer used in COVID-19 prevention

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    In the last years, forensic research has been focused on touch DNA in order to improve its evidential value in criminal activity investigations as well as to understand the variables impacting touch DNA. One of the emerging variables is represented by the use of alcohol-based sanitizers, which was suggested for hand hygiene during the COVID-19 pandemic. The aims of the present study were to assess the effect of a hand sanitizer on touch DNA deposition, transfer, and recovery and also to evaluate STR typing success, quality of DNA profiles, and personal identification. Before and after the use of an alcohol-based hand sanitizer, 20 volunteers deposited on glass surfaces 120 fingerprints, containing skin-derived or salivary DNA. Samples were quantified by real-time quantitative PCR (q-PCR), and 76 samples yielding > 15 pg/mu l were typed for 21 autosomal STRs by GlobalFiler (R) PCR Amplification Kit. DNA profiles were classified into single source, mixed, and inconclusive profiles, and a LR assessment was performed by comparison to the reference samples using LRmix Studio software. After the use of hand sanitizer, samples yielded lower quantities of recovered transferred DNA, especially considering samples containing salivary DNA (p < 0.05 by Friedman test). All the 76 amplified samples (63.3% of the total) showed at least 10 typed loci, and 83-100% of profiles were consistent with the reference ones on the basis of a LR value >= 10(6). Results showed that, although the hand sanitizer reduces the DNA recovering, touch DNA samples might still be useful for forensic personal identification even when hand sanitizers are used

    Unleash the potential of Fourier-Transform Infrared (FT-IR) spectroscopy to study extracellular vesicles cancer

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    Breast cancer remains a primary health concern among women worldwide, and insight into its initiation, progression, and metastasis are of the utmost importance. The role of Extracellular Vesicles (EVs), cell-derived membrane- surrounded vesicles, in cell-to-cell communication has long been recognized as a crucial component in these processes. A wide range of studies based on EVs are carried out on in vitro models, based on bi-dimensional (2D) cultures; these studies led to a greater understanding not only of the different mechanisms by which EVs contribute to tumor progression but also of their potential clinical use in diagnostics as biomarkers. Thus, investigating the molecular composition of EVs is of considerable importance, since it reflects the molecular composition of the parental cells [1]. Among all the techniques already set up, Fourier Transform Infrared spectroscopy (FTIR) has recently been introduced to the study of EVs. This innovative approach, commonly used in the material sciences field, enables fast label-free profiling, obtaining a distinctive molecular ‘fingerprint’ of EVs from minimal sample quantities, allowing the discovery of potential differences in molecular composition [2]. For this reason, for our study, EVs were isolated from two breast cancer cell lines, with different aggressiveness levels, cultured in 2D; EVs were isolated by ultracentrifugation technique and, once resuspended in a saline solution, they were analyzed for their FTIR spectra, to evaluate whether there could be differences that could reflect the different tumor grades. The results showed that there are some differences in several spectral regions of the two EVs samples, suggesting that the FTIR could allow the recognition of EVs, based on cell origin. However, the 2D models aren’t able to truthfully mimic the true complexity of the in vivo tumor microenvironment and the interactions mediated by EVs in it. Thus, more recent studies concerning EVs were focused on in vitro three-dimensional (3D) cell cultures, using tumor spheroids models [3]. To evaluate if there could be a difference in the molecular fingerprint of EVs derived from cells cultured in 2D or 3D, we isolated the EVs from breast tumor cells cultured by these two models and FTIR was performed on them. The results showed that the EVs isolated from 3D culture have different content in some molecular components compared to the EVs isolated from the respective cell lines cultured on 2D, suggesting that the composition of EVs is profoundly influenced by the cell culture methods and leading us to reflect on a careful evaluation of the most suitable cellular models in the in vitro studies. In conclusion, our preliminary data suggest that the FTIR offers new directions for EVs molecular fingerprints, making this tool potentially useful for biomarker discovery in liquid biopsy based on EVs
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