430 research outputs found
Lo studio della coscienza in età pediatrica e dei suoi correlati neurofisiologici: implementazione degli strumenti clinici con nuove tecniche di neurofisiologia sperimentale.
No full textBelow is the abstract for the final work package (WP4) only. Indeed, the thesis outlines the entire step-by-step process carried out. The machine learning algorithm proposed here is based on the combination of the Spectral Exponent and the Higuchi Fractal Dimension: the first stems from empirical and qualitative observations of the EEG signal, while the second is grounded in theoretical principles. The first three WP have shown that, although they measure different characteristics of brain electrical activity, both measures can discriminate between wakefulness (a state where consciousness is present) and deep sleep (a state without conscious content) in healthy subjects, regardless of age. Moreover, the spectral exponent was successfully applied in a specific physio-pathological model for DoC: hemispherotomy.
Abstract
Disorders of consciousness (DoC), such as coma, vegetative state and minimally conscious state, pre-sent significant challenges in clinical practice. These conditions, often resulting from severe traumatic brain injuries, anoxic insults or encephalopathies due to toxic-metabolic or immune-mediated causes, are associated with substantial diagnostic and prognostic difficulties. Standardized behavioral scales may fail to detect signs of "covert consciousness" in patients with severe sensory or motor pathway impairments, who are unable to demonstrate self-awareness or awareness of their surroundings.
This study aims to develop an advanced neurophysiological tool based on quantitative EEG features to provide prognostic insights in pediatric DoC. Conducted as a single-center prospective observational study between September 2021 and August 2024 at the Department of Women's and Children's Health, University Hospital of Padova, the study also seeks to standardize the multimodal assessment of pedi-atric DoC patients. This includes the integration of standardized clinical scales, neurophysiological techniques and neuroimaging to identify unique features within this population.
A comprehensive evaluation of pediatric DoC patients was performed using a multimodal assessment approach adapted from adult guidelines. The study included patients aged 9 months to 18 years admit-ted to the Department during the study period. The assessment encompassed clinical diagnosis using the Coma Recovery Scale for Pediatrics (CRS-P) for children over 1 year of age, structural cerebral MRI and a series of neurophysiological assessments, including standard EEG, SEP, BAEPs, VEPs, and nerve conduction studies. A machine learning algorithm was then developed using two key quantitative EEG features—spectral exponent and Higuchi Fractal Dimension (HFD)—which have demonstrated strong capabilities in discriminating wakefulness from sleep in healthy pediatric subjects. The algo-rithm was initially developed using EEG data from 89 healthy children, trained on 16 additional normal EEG recordings, and subsequently tested on 10 pediatric DoC patients.
Among the 10 DoC patients studied, 4 had an unfavorable outcome, while 6 showed improvement to at least a minimally conscious state. Predictive modeling indicated that none of the conventional clinical and instrumental variables could reliably predict outcomes, though the small sample size is a notable limitation. However, the algorithm successfully predicted favorable outcomes in 4 of the 6 cases, cor-rectly identifying wakefulness in EEGs of patients clinically diagnosed as being in a vegetative state. These findings highlight the algorithm's potential to aid in predicting the progression of pediatric DoC.
This study successfully developed a machine learning algorithm based on quantitative EEG features, showing promising prognostic capabilities in pediatric disorders of consciousness. Implementing this tool in clinical practice could enhance the accuracy of patient evaluations and significantly contribute to the understanding and management of pediatric DoC
Giovan Domenico Scevolini e una misteriosa accademia udinese fra astrologia, letteratura e sospetti di eresia
No full textNegli anni attorno al 1560, alcuni dei più bei nomi dell’élite udinese si riunirono presso il salotto del nobile Mario Savorgnan, dando vita ad un’“accademia” che resta tuttora piuttosto misteriosa. La maggior parte delle informazioni su di essa è ricavabile dai documenti legati ad un’interessante figura di intellettuale animato da inquietudini religiose, il romagnolo Domenico Scevolini da Bertinoro. Costui tenne presso l’“accademia” una serie di lezioni sui fondamenti dell’astronomia e su alcuni sonetti di Petrarca, oltre a discutere liberamente di temi religiosi assai delicati in occasioni più informali (già frate domenicano, lo Scevolini aveva deposto l’abito prima del soggiorno udinese). L’Inquisizione si insospettì, tanto da sottoporre l’ex-frate ad un processo per eresia. Dagli atti del processo, in cui furono chiamati a testimoniare vari “academici udinesi”, otteniamo preziose informazioni sull’“accademia” stessa.
Con la presente lettura, si vuole offrire una ricostruzione dell’attività dello Scevolini e dell’accademia sulla base dei documenti a disposizione. Particolare attenzione è dedicata ad un testo inedito e poco noto dello Scevolini, la Lettera sopra la bellezza del sito d’Udine e di tutto ’l Friuli (1561), indirizzata al vicario patriarcale Jacopo Maracco. Nella Lettera, lo Scevolini dimostra l’eccellenza del sito di Udine e del Friuli esaminando i vantaggi della conformazione naturale e della posizione della regione, le bellezze del territorio e il pregio dei suoi prodotti, l’avvenenza e il vigore della gente che vi abita e «il gran numero de’ bellissimi ingegni in tutte le professioni», soffermandosi su alcune personalità in particolare
Jacopo Sadoleto: De Laocoontis statua (1506) (FONTES 5)
No full textWhen the statue of Laocoon and his two sons in the clutch of the serpents was discovered near the Colosseum at the beginning of 1506 the excitement was great, and young Jacopo Sadoleto, later a cardinal, then a devoted humanist, composed a poem on this masterpiece based on classical verse. Sadoleto’s text is not without echoes of Vergil’s famous lines about Laocoon and his fate, and with an astonishingly independent judgment on the quality of the subject. This text has been printed in various modern publications on Sadoleto, respect to the Laocoon, but only the edition by the present author, produced in 1992, offered a critical text based on a comparison of all extant printed versions from the 16th and 17th centuries, along with a brief linguistic commentary. Since no other attempt to recover the original text and no more recent commentary have hitherto appeared, the text and commentary of the 1992 publication are here reprinted in a partly abridged, partly enlarged form in order to provide the interested scholar with a reliable text and some linguistic basics as materials for further interpretation
Una lettura vichiana, pedagogica e risorgimentale: il discorso «Omero e Dante proposti alla gioventù come modelli di morale e di lingua» di G. F. Banchieri presso il Ginnasio Liceale di Udine (1854)
No full textL’intervento mira ad analizzare il poco noto discorso Omero e Dante proposti alla gioventù come modelli di morale e di lingua (1854), pronunciato presso l’odierno Liceo Classico “Jacopo Stellini” di Udine dal sacerdote Gian Francesco Banchieri, professore di greco presso il medesimo liceo e ispettore scolastico distrettuale. Il Banchieri legge Omero e Dante da una prospettiva romantica, avvalendosi per le sue osservazioni degli scritti del Cesarotti, del Vico e dello Stellini, filosofo friulano di impostazione vichiana. Il testo è interessante anche per altri motivi: per il contenuto intrinseco delle considerazioni linguistiche e allegorico-morali; per l’approccio in chiave risorgimentale alla Commedia, che viene letta come appello all’unità degli Italiani (considerando che si tratta di un discorso pubblico tenuto all’altezza del 1854, il Banchieri si dimostra audace a tal riguardo: del resto, egli fu uno dei più autorevoli e ferventi sostenitori della causa dell’unificazione italiana all’interno del clero udinese, e per questo ebbe problemi con le gerarchie ecclesiastiche); per il legame con la realtà scolastica dell’epoca, tenendo presente che il Banchieri stesso evidenzia l’utilità dell’insegnamento di Omero e di Dante in relazione agli obiettivi ispiratori di un’importante riforma della scuola varata nel Lombardo-Veneto pochi anni prima
Maiko Favaro, Ambiguità del petrarchismo. Un percorso fra trattati d’amore, lettere e templi di rime (Milano, FrancoAngeli, 2021)
No full textPlausibility or truth. Archival notes and reflections on the canvas of the ‘Militant and triumphant Church’ ascribed to Jacopo Zucchi
No full textWhile retracing the traditional history of the painting, which was fi rst ascribed to Federico Zuccari and later to
Jacopo Zucchi, the author hereby presents the long and painstaking research that has gradually confi rmed this
second hypothesis. The reader will, therefore, fi nd a synthesis of the history of this painting, which was surely
enough fi rst hosted in St Peter's Basilica, then moved to the Church of St Catherine of Alexandria and fi nally to
the Vatican Sacristy. Based on a number of inconsistencies which emerged during archival research, doubts still persist with regard to
the historicity of this historical-artistic tradition. Despite the fact that scholars are fi rmly inclined to ascribe the
painting to Zucchi, some unpublished documents tend to undermine this assumption, while still implying that the
painting might be by an artist of the Zuccari famil
Monumenti veneziani di varia letteratura : per la prima volta pubblicati nell'ingresso di Sua Eccellenza messer Alvise Pisani, cavaliere, alla dignità di procuratore di San Marco.
No full textIllustrations: engraved allegorical frontispiece, title-page vignette with Pisani arms, and 3 headpieces: one depicting the siege of Zadar and two medallions with portraits of Bembo and Galileo, both have legend: Ex museo Pisanorum. All unsigned.Signatures: pi³ A-H⁴.Name of editor, Jacopo Morelli, at head of dedicatory letter addressed to Francesco Pisani.The last page is blank.Includes bibliographical references.Cinti, D. Bib. galileiana,Carli & Favaro. Bib. galileiana,Morazzoni, G. Libro illustrato veneziano del Settecento,Mode of access: Internet.Binding: publisher's pink paper boards, with woodcut ill. on front and back covers (Pisani arms and monogram)
Il generale si candida. Élite militare e competizione elettorale nell'Italia liberale
No full textConsidering the military as an élite among the others that ruled the Italian liberal state, the author proposes an analysis of some election campaigns in which high-ranking army officers were involved as candidates. The social networks and the personal strategies implemented by the officers are shown through their private and family archives, in particular the one related to count Luigi Majnoni d’Intignano, a Lombard aristocrat who ran for a seat twice, and under very different conditions. In the end, the research allows a deep rethinking about the role and the representation of the relationship between Italian military élite and politics before the Great War
Francisco de Assis na Legenda Áurea de Jacopo de Varazze
No full textO objetivo deste artigo é propor uma análise da presença de São Francisco de Assis na Legenda Áurea e os recursos intelectuais de seu autor, Jacopo de Varazze, quase sempre utilizados com o fim de evangelizar e responder às novas necessidades espirituais dos séculos XII e XIII, nos sermões dos dominicanos. Para tanto será discutido o contexto histórico desse período como grande responsável, não apenas pela formação do clérigo Jacopo de Varazze e sua obra, mas também pelo surgimento das ordens mendicantes e seus idealizadores. The purpose of this article is to propose an analysis about the presence of Saint Francis of Assisi in the Golden Legend and the intelectual prowess of its author, Jacopo de Varazze, often used in order to evangelize and meet the spiritual needs of the Twelfth and Thirteenth Centuries, in the sermons of the domicians. To do so will discuss the historical context of this period as largely responsible, not only for the formation of Jacopo de Varazze and his work, but also by the emergence of the mendicant orders and their creators
Jacopo Sansovino a ca’ Tiepolo
No full textUsing unpublished documents of the Venetian State Archive, the author tries to reconstruct the history of the
former Tiepolo palace in the ward of San Felice as well as a precise chronology of the restoration works conducted
by Jacopo Sansovino in 1560 for Alvise Tiepolo, Procurator of Saint Mark’s. It appears that the architect
not only consolidated the foundations, but also divided the palace in two independent houses using a doubleramp
interior staircase according to a typical 16th century and remade the windows of the lower piano nobile
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