1,721,123 research outputs found
Transfer of only a single embryo in in-vitro fertilisation
In order to obtain high pregnancy rates per IVF cycle, ovarian stimulation is employed to produce multiple embryos. The best embryos are transferred into the uterus and the remainder are frozen for possible use in later cycles. Despite limiting the number of transferred embryos, more than half of all IVF babies are the result of multiple pregnancies. The associated morbidity and costs have led to calls for the adoption of single embryo transfer. New techniques such as pre-implantation genetic screening for aneuploidy have enabled better embryo selection with optimal chances of a healthy child. Milder ovarian stimulation protocols may further reduce the morbidity and costs of IVF cycles. Improved cryopreservation techniques should improve the chances of pregnancies in subsequent cycles using excess embryos. The definition of success in IVF should be changed from number of children per IVF cycle to number of children born after singleton pregnancies per IVF treatment started
A Hopf algebraic approach to the theory of group branchings
We describe a Hopf algebraic approach to the Grothendieck ring of representations of subgroups of the general linear group GL(n) which stabilize a tensor of Young symmetry . It turns out that the representation ring of the subgroup can be described as a Hopf algebra twist, with a 2-cocycle derived from the Cauchy kernel 2-cocycle using plethysms. Due to Schur-Weyl duality we also need to employ the coproduct of the inner multiplication. A detailed analysis including combinatorial proofs for our results can be found in math-ph/0505037. In this paper we focus on the Hopf algebraic treatment, and a more formal approach to representation rings and symmetric functions
Aspects of ovarian follicle development throughout life
The pool of primordial follicles present in the female ovary reaches its maximum number around 20 weeks of gestational age and then decreases in a logarithmic fashion throughout life until complete depletion occurs around the age of the menopause. Reproductive life is initiated when less than 10% (0.5 million) of primordial follicles are left. The entire growth trajectory of the follicle takes at least 3 months. Follicle growth up to the antral stage occurs during fetal life and infancy. While the role of gonadotropins in early follicular development remains controversial, the last 2 weeks of development are FSH dependent. The intercycle rise in FSH and decreasing levels thereafter are crucial for recruitment of a cohort of healthy, early antral follicles and subsequent single dominant selection. Following puberty, anovulation may persist for years and this may presage the development of adult anovulatory infertility. The menopause is preceded by a period of reduced fertility. The development of reliable and sensitive markers for ovarian ageing will be the challenge of the near future
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Ovarian reserve
The tendency to delay childbirth has increased the importance of ovarian reserve as a determinant of infertility treatment outcome. In the context of assisted reproduction technology, effective strategies to overcome the impact of ovarian aging and diminished ovarian reserve on pregnancy chances remain elusive. Markers of ovarian reserve are increasingly used to aid management and counseling of these patients. Proper interpretation of currently applied hormonal markers, ultrasound parameters, and hormone challenge tests requires an understanding of what constitutes and determines ovarian reserve. This article addresses these aspects and highlights recent developments in the field
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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