1,721,055 research outputs found
La determinazione del prezzo dei farmaci innovativi in Italia con procedura centralizzata europea
No full textEliciting preferences to inform patient-centred policies: The case of psoriasis
No full textObjective: To assess patient preferences for psoriasis treatment features and to investigate the heterogeneity of preferences among patients with different socio-demographic and disease-related characteristics. Methodology: Adiscrete choice experiment was conducted on adult patients with moderate to severe plaque-type psoriasis during a routine visit to their physician at 15 centres in Italy. We investigated the preferences of patients with respect to five treatment attributes: (1) mode and frequency of administration; (2) time to improvement; (3) time free of symptoms; (4) unintended life expectancy reduction resulting from treatment; and (5) monthly treatment cost. The heterogeneity of preferences was investigated in a mixed logit model with normally distributed random coefficients. Results: Overall, patients preferred the subcutaneous or intravenous route of administration (versus oral administration) and treatments that took less time to show improvement, ensured a longer time free of symptoms, involved a lesser reduction in life expectancy and had lower costs. There was significant preference heterogeneity for all attributes. The cost attribute was found to be significantly more important to females and to older patients (above 60 years of age). Older patients placed significantly greater emphasis on reduced life expectancy, whereas the time free of symptoms was significantly less important to them than to patients under 60 years of age. Patients with higher scores on the Dermatology Life Quality Index (DLQI) placed higher value on the time free of symptoms than those with lower DLQI scores. For the overall sample, the marginal willingness to pay (WTP) for a month's reduction in the time to improvement was €32.4, whereas the WTP for one additional month without symptoms was significantly higher (€68.2). Conclusion: Patient-centred policies should consider the heterogeneity of patients' expectations to identify individualized treatments that would aid in optimizing patient satisfaction and wellbeing, as well as overall treatment effectivenes
Excess hospitalizations and in-hospital mortality associated with seasonal influenza in Italy: a 11-year retrospective study
No full textThe Treatment experience, burden, and unmet needs (TRIBUNE) study - measuring the socioeconomic consequences of Multiple Sclerosis
No full textThe Treatment experience, burden, and unmet needs (TRIBUNE) study - measuring the socioeconomic consequences of Multiple Sclerosis.
No full textDecisioni e leve di service management
No full textIl capitolo illustra quali sono le leve di service management che un manager può utilizzare per rinnovare il sistema dei servizi dell'amministrazione pubblica. In particolare si sofferma sul ruolo dello street level bureaucrats nell'implementazione delle politiche pubblich
L'evoluzione del sistema di pubblico impiego
No full textIl capitolo approfondisce i caratteri distintivi del sistema di pubblico impiego inteso sia come insieme di persone sia come insieme delle regole e meccanismi operativi che qualificano le relazioni fra datore di lavoro e lavoratore all'interno delle amministrazioni pubblich
E-government e innovazione nei servizi pubblici
No full textIl capitolo illustra l'impatto dell'information and communication technology (ICT) sulle modalità di funzionamento ed erogazione dei servizi della pubblica amministrazion
- …
