105 research outputs found
New Mediterranean Biodiversity Records (December 2011)
No full textThe present work reports on recent biodiversity records of Mediterranean native species such as Olindias phosphorica in the Turkish Aegean Sea and extended distribution of eleven alien species in the Mediterranean. These are: Bursatella leachi (Mollusca, Gastropoda: Algeria); Callinectes sapidus (Crustacea, Decapoda: Greek Ionian Sea); Caprella scaura (Crustacea, Amphipoda: Mar Piccolo of Taranto); Fistularia commersonii (Fish: Saronikos Gulf, Aegean Sea); Sphoeroides pachygaster (Fish: South Turkey); Musculista perfragilis (Mollusca, Bivalvia: South Turkey); Sepioteuthis lessoniana (Mollusca, Cephalopoda: central eastern coast of Tunisia); Flabellina rubrolineata (Mollusca, opisthobranchia: central Aegean, Greece); Hesionura serrata (Polychaeta: Apulian coast); Stephanolepis diaspros (Fish: Saronikos Gulf, Aegean Sea); and Parvocalanus crassirostris (Crustacea, Copepoda: Lesvos Island, Greek Aegean Sea).Scientific and Technical Research Council of Turkey (TUBITAK) [109Y284]The authors (Cem Cevik, Levent Cavas, Osman Bans Derici and Fatma Cevik) are grateful to the Scientific and Technical Research Council of Turkey (TUBITAK) for financial support of the study (Grant number 109Y284). Abdallah Hattour would like to thank the fishermen of Salakta who provided the examined specimen of Sepioteuthis. Souad Lamouti would like to thank Mr Adlane Ferchouli for his help in the field
First record of phyllorhiza punctata von lendenfeld, 1884 (Scyphozoa: Rhizostomeae: Mastigiidae) from Turkey
No full textThe Australian spotted jellyfish Phyllorhiza punctata has been reported from several locations in the Mediterranean, but the present report is the first record from Turkish waters. Juveniles of the Erythrean alien shrimp scad, Alepes djedaba, were observed nestling among its tentacles. Possible vectors are mentioned. © 2011 The Author(s)
DIABETES-INDUCED ADHESIVE CAPSULITIS: THE ROLE OF RADIAL EXTRACORPOREAL SHOCK WAVE THERAPY ON THE SHOULDER MUSCLES MECHANICAL PROPERTIES
No full textMutluay, Fatma/0000-0003-1432-0913[No Abstract Available]Science Citation Index Expande
New formulae for Zagreb indices
No full textInternational Conference on Numerical Analysis and Applied Mathematics (ICNAAM) -- SEP 19-25, 2016 -- Rhodes, GREECEIn this paper, we study with some graph descriptors also called topological indices. These descriptors are useful in determination of some properties of chemical structures and preferred to some earlier descriptors as they are more practical. Especially the first and second Zagreb indices together with the first and second multiplicative Zagreb indices are considered and they are calculated in terms of the smallest and largest vertex degrees and vertex number for some well-known classes of graphs.Uludag UniversityUludag University [F-2015/17, F-2015/23]; Selcuk UniversitySelcuk UniversityThe first author was supported by the Research Fund of Uludag University project no: F-2015/17, F-2015/23. The last author is supported by Selcuk University Research Fund
Impact of aerobic training with and without whole-body vibration training on metabolic features and quality of life in non-alcoholic fatty liver disease patients
No full textThe present study examined the effectiveness of adding exercises with whole-body vibration (WBV) to aerobic training in terms of metabolic features and quality of life. Patients with non-alcoholic fatty liver disease (NAFLD), confirmed on imaging, underwent an 8-week individualized exercise program randomized between aerobic training with and without WBV. Training was performed at 60-80% heart rate workload for 165 min/week. The WBV amplitude was 2-4 mm and the training frequency was 30 Hz, for 15 min. Assessments were carried out on surrogate scores of steatosis and fibrosis including transient elastography (FibroScan), metabolic features (biochemical analysis) and quality of life (SF-36). Insulin resistance was markedly reduced ( -2.36; 95% CI: -4.96 to -0.24; P: 0.049) in aerobic training with WBV. The decrease in serum aspartate transaminase was significantly greater in aerobic training without WBV ( -14.81; 95% CI: -23.36 to -6.25; P: 0.029). There were no significant differences between groups for the other metabolic features (P< 0.05). All quality of life well-being domains improved in both groups (P< 0.05). Given this reduction in insulin resistance, WBV can usefully be added to aerobic training. However, WBV did not provide further benefits in improving metabolic properties or quality of life. (C) 2020 Elsevier Masson SAS. All rights reserved
Cyclosporine-A induces apoptosis in human prostate cancer cells PC3 and DU145 via downregulation of COX-2 and upregulation of TGF beta
No full textBackground: Potential targets for prostate cancer therapy are urgently needed for curative of patients. Cyclosporine-A (CsA), an immunosuppressive and a selective cyclooxygenase-2 (COX-2) inhibitor, exerts antitumor activity. However, the molecular effects of CsA is not fully understood in prostate cancer. In this research, we sought to determine role and mechanism of CsA in prostate cancer. Materials and methods: PC3 and DU145 cells were treated with CsA time (12, 24, 48 h) and dose dependent (2.5, 10, 25 mu M) and cell survival, migration, colony formation, expression of apoptosis related proteins/genes using MTT assay, scratch assay, Western blotting/qPCR. At the same time, cells treated with CsA to test on the effects of COX-2 promoter activity using luciferase reporter plasmid. Lastly, functional role in the CsA treatment prostate cancer cells were interrogated for relationship of TGF beta, Akt, caspases and COX-2. Results: These study findings provided direct evidences that the CsA induced apoptosis and downregulated migration. Conclusions: CsA downregulated Akt as well as COX-2 and upregulated TGF beta, resulting in the suppression of cell migration which was augmented a potential therapeutic of CsA in prostate cancer cells.Cumhuriyet University Research Grant [ECZ-003/ECZ-008]; Scientific and Technological Research Council of Turkey (TUBITAK) [214Z057]; Science Academy's Young Scientist Award (BAGEP)-2016The authors are grateful to Dr. Neerja Kaushik Basu for the kind gift of p-COX-2-Luc reporter plasmids. Authors would like to thank Mustafa Ergul and H. Eren Bostanci from Faculty of Pharmacy in Cumhuriyet University. This work was supported by the Cumhuriyet University Research Grant (Projects ECZ-003/ECZ-008) and by a grant (214Z057) from the Scientific and Technological Research Council of Turkey (TUBITAK) and Science Academy's Young Scientist Award (BAGEP)-2016 to Dr. Ozge Cevik
Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy
No full textNeurofibrillary tangles (NFTs) are associated with neuronal loss and correlate with cognitive impairment in Alzheimer disease, but how NFTs relate to neuronal death is not clear. We studied cell death in Tg4510 mice that reversibly express P301L mutant human tau and accumulate NFTs using in vivo multiphoton imaging of neurofibrillary pathology, propidium iodide (PI) incorporation into cells, caspase activation, and DNA labeling. We first observed that in live mice, a minority of neurons were labeled with the caspase probe or with PI fluorescence. These markers of cell stress were localized in the same cells and appeared specifically within NFT-bearing neurons. Contrary to expectations, the PI-stained neurons did not die during a day of observation; the presence of Hoechst-positive nuclei in them on the subsequent day indicated that the NFT-associated membrane disruption, as suggested by PI staining, and caspase activation do not lead to immediate death of neurons in this tauopathy model. This unique combination of in vivo multiphoton imaging with markers of cell death and pathological alteration is a powerful tool for investigating neuronal damage associated with neurofibrillary pathology
Replication data for: Source apportionment of fine particulate matter in Houston, Texas: Insights to secondary organic aerosols
No full textThis dataset contains the data published in figures and tables of the journal article entitled: "Source apportionment of fine particulate matter in Houston, Texas: Insights to secondary organic aerosols". Published in the Journal of Atmospheric Chemistry and Physics, 2018. Author list: Ibrahim M. Al-Naiema, Anusha P. S. Hettiyadura, Henry W. Wallace, Nancy P. Sanchez, Carter J. Madler, Basak Karacurt Cevik, Alexander A. T. Bui, Josh Kettler, Robert J. Griffin, and Elizabeth A. Stone
Replication data for: Source apportionment of fine particulate matter in Houston, Texas: Insights to secondary organic aerosols
No full textThis dataset contains the data published in figures and tables of the journal article entitled: "Source apportionment of fine particulate matter in Houston, Texas: Insights to secondary organic aerosols". Published in the Journal of Atmospheric Chemistry and Physics, 2018. Author list: Ibrahim M. Al-Naiema, Anusha P. S. Hettiyadura, Henry W. Wallace, Nancy P. Sanchez, Carter J. Madler, Basak Karacurt Cevik, Alexander A. T. Bui, Josh Kettler, Robert J. Griffin, and Elizabeth A. Stone
Bitter melon (Momordica charantia) fruit extract ameliorates methotrexate-induced reproductive toxicity in male rats
No full textObjective: Methotrexate (MTX) is a drug commonly used for the treatment of malign neoplastic and inflammatory diseases. Anti-oxidant and anti-inflammatory effects of bitter melon (BM) were reported. The aim of this study was to examine the effects of BM fruit extract on MTX-induced testicular and epididymal damage. Materials and Methods: Sprague Dawley male rats were divided into three groups (n=8) as control, MTX and MTX+BM. A single dose of MTX (20 mg/kg) was injected intraperitoneally to the MTX and MTX+BM groups. BM fruit extract (600 mg/kg) was applied to the MTX+BM group orally for 5 days. Testes were examined for general histopathology, proliferating and apoptotic cells. The epididymis samples were used for the evaluation of sperm morphology. Oxidative and inflammatory markers were analysed biochemically. Results: Increased abnormal spermatozoa, degenerated seminiferous tubules with increased apoptotic cells and decreased proliferative cells were observed in the MTX group. TNF-alpha, IL-1 beta, 8-hydroxy-2-deoxyguanosine and caspase-3 levels increased, superoxide dismutase and catalase levels decreased in both testis and epididymis samples. All these histological and biochemical parameters were ameliorated in the MTX+BM group. Conclusion: Methotrexate causes testis damage by decreasing spermatogenic cells and increasing apoptosis through oxidative stress and inflammation. BM extract improves testis and epididymis damage with its possible anti-oxidant and anti-inflammatory effects
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