1,720,965 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Purification and Analysis of HCV NS3h Helicase
No full textThe Hepatitis C Virus (HCV) is a small enveloped positive-sense single-stranded RNA virus that infects millions of individuals worldwide. It is a prominent cause of liver cirrhosis, hepatocellular carcinoma, and chronic hepatitis. The blood bourn pathogen encodes a single polyprotein that is cleaved by both host and viral proteases into 10 nonstructural and structural proteins. The third HCV nonstructural protein (NS3) is a complex molecule that has been presumed as essential for viral replication, and has therefore been the target of antiviral therapy for HCV. NS3 contains a helicase whose activity is associated with 450 residues of the NS3 COOH-terminal. To understand the binding and association of NS3h with DNA when the DNA is unwound, the NS3h protein was purified as cyan fluorescent fusion protein (CFP-NS3h). After the purification of the fusion protein, a ATPase assay was used to assess the protein function. The results of the assay showed that the fluorescently marked CFP-NS3h had the same ATPase activity in the presence of PolyU RNA as a unmarked NS3h protein. Finally, FRET assays were performed to determine the binding capacity of the protein to DNA
Identification of Borrelia burgdorferi in the Brains of Regulatory T Cell Depleted Mice
No full textLyme disease, caused by the spirochete bacterium Borrelia burgdorferi, is a significant health concern. According to CDC data, an estimated 300,000 people are diagnosed with the disease every year. It is spread through the bite of a black legged tick infected by the bacterium, and may cause symptoms in the neurological, musculoskeletal, and cardiac systems. However, not all individuals infected by B. burgdorferi develop the symptoms of Lyme disease, suggesting that there are immune factors regulating the severity of symptoms following infection. We hypothesize that CD4+CD25+Foxp3+ regulatory T (Treg) cells prevent B. burgdorferi from entering the central nervous system (CNS). To investigate this phenomenon, our lab aims to determine how infection with B. burgdorferi will compromise the blood brain barrier of mice, allowing the spread of the bacteria into the CNS. We hypothesize that without Treg functionality, B. burgdorferi will disseminate to the brain. We intend to determine the efficiency of applying this model to measure neurological symptoms of Lyme disease, as there is currently no known model in practice at this time. Therefore, the implications of this research are essential to understanding the role of Treg cells in preventing neural symptoms of Lyme disease, a step towards preventing the disease progression, while also formulating a model of study to do further investigative research on a prominent health concern
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
