4,402 research outputs found
Lepeophtheirosis (Lepeophtheirus salmonis)
No full textThis book chapter describes various aspects of lepeophtheirosis caused by Lepeophtheirus salmonis: epidemiology, geographical distribution, transmission, control and prevention, diagnosis, impacts on reservoir hosts, and chemical and non-chemical control methods
Differential expression of the pro-inflammatory cytokines IL-1β-1, TNFα-1 and IL-8 in vaccinated pink (Oncorhynchus gorbuscha) and chum (Oncorhynchus keta) salmon juveniles
No full textLaboratory-reared pink and chum salmon juveniles (∼2g) received an intraperitoneal injection with a commercial, unadjuvanted Aeromonas salmonicida bacterin or sterile saline. Relative to elongation factor-1A, expression levels of genes encoding the proinflammatory cytokines interleukin-1β-1 (IL-1β), tumour necrosis factor-α-1 (TNFα) and interleukin-8 (IL-8) in pools of kidney and liver were examined 6- and 24-h after injection. Expression of IL-1β was significantly elevated in pink and chum salmon by 6-h, and declined in pink salmon but not in chum salmon by 24-h. Similarly, expression of TNFα was significantly elevated in both species at 6h and only in chum salmon after 24-h. Expression of IL-8 was significantly elevated in both species at 6- and 24-h after injection. Expression of the three proinflammatory cytokine genes differed between salmon species both in the timing and magnitude of their expression. The significance of these differences with respect to immune function in these fish requires further research.Source type: Electronic(1
George McClellan [1849-1913]: A Memoir read before the College of Physicians of Philadelphia, by J. Chalmers Da Costa, M.D., LL.D., Samuel D. Gross Professor of Surgery in Jefferson Medical College
No full textA memoir of Dr. George McClellan (1849-1913). Dr. McClellan was the author of the book Regional Anatomy, and grandson of George McClellan, M.D.; the founder of Jefferson Medical College
2000 Commencement Address: G. Timothy Johnson, M.D.
No full textTimothy Johnson, M.D., medical editor for ABC News will deliver the principal address and receive an honorary degree at the 154th commencement exercises at the College of the Holy Cross on Friday, May 26, beginning at 10:30 a.m. at Fitton Field.
Johnson, one of the nation’s leading medical communicators of health care information, has provided commentary on medical problems and answers for viewers since 1975. In addition to commentary on Good Morning America, Johnson provides on-air analysis of medical news for World News Tonight, Nightline and 20/20. He consults with ABC News regardingcoverage of medical news. He is also medical editor for WCVB-TV, Channel 5 in Boston.
Johnson holds joint positions in medicine at Harvard University and Massachusetts General Hospital in Boston. He is the founding editor of the Harvard Medical School Health Letter and co-editor of the Harvard Medical School Health Letter Book. He is also coeditor of the book, “Your Good Health,” published by Harvard Press, as well as co-author with former US Surgeon General Dr. C. Everett Koop of the book, “Let’s Talk,” published by Zondervan in 1992.
He originally intended to join the ministry and graduated from the North Park Seminary in 1963. Two years later he decided to enter medicine. Johnson, who is a Phi Beta Kappa graduate of Augustana College, graduated summa cum laude from Albany Medical College and holds a master’s degree in public health from Harvard University. Johnson served as an assisting minister at the Community Covenant Church in West Peabody, Mass.https://crossworks.holycross.edu/commence_address/1012/thumbnail.jp
Novel gamma-ray and thermal-neutron scintillators: Search for high-light-yield and fast-response materials
No full textIn this dissertation, we present bromide and iodide scintillators which have been investigated for the past four years. Three major groups of compounds were studied; lanthanide trihalides LnX3, (pseudo)-elpasolites M2ALnX6 and ternary halides AmLnnXo where M and A are alkali cations, Ln is a rare earth cation and X is a halide anion. Some materials show interesting gamma-ray-scintillation properties. LuI3: Ce3+, one of lanthanide trihalides, has a record high light output of 98,000 photons/MeV and a fast response of 35 ns. Other two groups, (pseudo)-elpasolites and ternary halides, show relatively low light yields. For thermal neutron scintillator, we focused with (pseudo)-elpasolites M2LiLnX6 and ternary halides LimLnnXo groups. Rb2LiYBr6: Ce3+ shows an excellent neutron peak resolution of 3.6%. This is the best neutron peak resolution ever reported. Together with the large Alpha/Beta ratio of 0.74, Rb2LiYBr6: Ce3+ offers the possibility of excellent neutron/gamma-ray discrimination. The highest thermal neutron scintillation light yield of 83,000 photons/neutron is also reported for Rb2LiYBr6: Ce3+.Applied Science
Robust energy transfer mechanism via precession resonance in nonlinear turbulent wave systems
No full textA robust energy transfer mechanism is found in nonlinear wave systems, which favours transfers towards modes interacting via triads with nonzero frequency mismatch, applicable in meteorology, nonlinear optics and plasma wave turbulence. We emphasise the concepts of truly dynamical degrees of freedom and triad precession. Transfer efficiency is maximal when the triads' precession frequencies resonate with the system's nonlinear frequencies, leading to a collective state of synchronised triads with strong turbulent cascades at intermediate nonlinearity. Numerical simulations confirm analytical predictions
Ontogeny of the immune system in Acipenserid juveniles
No full textSturgeon aquaculture has increased considerably worldwide but little is known about their immunological development and competence in early life stages. Culture of larvae is one of the most critical stages in intensive sturgeon farming, often associated with high mortality rates. The objective of this study was to characterize the developmental morphology (light and transmission electron microscopy, LM and TEM) of the meningeal myeloid tissue, spleen and thymus in Atlantic sturgeon (Acipenser oxyrinchus oxyrinchus) from hatching until 5months old (2895°C day (dd)). The spleen was first visible on 541dd larvae LM sections and the other two immune organs in 768dd samples (approximately 400 and 600dd after onset of feeding). Generally, younger fish had significantly higher percentages of undifferentiated cells (meningeal myeloid tissue and spleen) and effective adaptive immune competence would not be expected in these fish on the onset of feeding, but further functional immune assessment is needed
SOME SOCIAL AND POLITICAL VIEWS M.D. SKOBELEVS
No full textThe article analyzes social and political views of M.D. Skobelev, an outstanding military commander, a hero of the Russian-Turkish and Balkan wars¸ who contributed greatly to the entry of Central Asia (Turkestan) and other regions into the Russian Empire. The author concludes that M.D. Skobelev’s views were close to those of the Slavophiles, though they differed greatly on a number of key issues. They both considered that it was necessary to restore national identity, to consolidate Orthodoxy, to give up European values to the detriment of national ones, to search for the own development way instead of the western one, which was deadlock and destructive
Combinatorial effects of administration of immunostimulatory compounds in feed and follow-up administration of triple-dose SLICE® (emamectin benzoate) on Atlantic salmon, Salmo salar L., infection with Lepeophtheirus salmonis
No full textSeveral immunostimulatory feed additives have shown the ability to induce protective responses in Atlantic salmon to infection with Lepeophtheirus salmonis. However, even the most encouraging results rarely surpass a 50% protective index in the host. That fact coupled with the well-documented limitations of single-therapy strategies in the effective management of parasitic infections generally make it imperative to identify therapies that can be combined in an integrated pest management approach for sea lice. With this in mind, we hypothesized that immunostimulatory feeds could enhance the protection provided by SLICE® emamectin benzoate (EMB). To test this hypothesis, Atlantic salmon were fed one of two different immunostimulatory feeds (CpG ODN or Aquate®) for c. 7 weeks, challenged with L. salmonis copepodids early within that immunostimulatory feed period and then placed on a triple-dose (150 μg kg(-1) ) feed of SLICE® for 1 week following the completion of the immunostimulatory feeding period. CpG ODN (2 mg kg(-1) ) and the commercial yeast extract (Aquate® 0.2%) inclusion in feeds were able to successfully induce inflammatory gene expression (interleukin-1β) in the head kidneys of infected fish at 13 and 26 days post-exposure (DPE), and 13 DPE, respectively. Lice burdens were lower on fish fed CpG ODN (18%) or Aquate® (19%) diets; however, due to variability, these were not statistically significant over time. Despite no statistically significant reductions in lice numbers, by 33 DPE fish on immunostimulatory feeds had significantly reduced cortisol levels when compared to infected fish on control diet. Cortisol levels in fish receiving an immunostimulatory diet were no different from initial baseline levels prior to infection, whereas the levels in control diet fish were significantly elevated from all other time points. Despite the positive effects on infection of fish fed immunostimulatory feeds, no synergism was observed with follow-up treatment with SLICE® . In fact, highest survival of lice was observed in fish with prior immunostimulation
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