1,362,596 research outputs found

    Declaración de Giuseppe Fanelli

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    2 ImágenesDeclaración de Giuseppe Fanelli ante al Gobierno Pontificio en la que se compromete a pagar, a más tardar en el año de 1860, el dinero que le debe a Nicola Mariotti. Fechada en Falconara

    Correction to: Curve of Spee modification in different vertical skeletal patterns after clear aligner therapy: a 3D set-up retrospective study (Progress in Orthodontics, (2024), 25, 1, (5), 10.1186/s40510-023-00503-1)

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    Correction to: Prog Orthod.25, 5 (2024) https://doi.org/10.1186/s40510-023-00503-1. Following publication of the original article [1], the authors identified an error in the author names of the author group as the given name and family name were erroneously transposed. The incorrect author names are: Ciavarella Domenico, Fanelli Carlotta, Suriano Carmela1, Campobasso Alessandra, Lorusso Mauro, Ferrara Donatella, Maci Marta, Esposito Rosa and Tepedino Michele The correct author names are: Domenico Ciavarella, Carlotta Fanelli, Carmela Suriano, Alessandra Campobasso, Mauro Lorusso, Donatella Ferrara, Marta Maci, Rosa Esposito and Michele Tepedino The author group has been updated above and the original article [1] has been corrected

    Le pietre di Franco Fanelli, incisore

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    In occasione della mostra allestita a Pisa (Museo della Grafica), il contributo è dedicato alle incisioni dell’artista torinese Franco Fanelli, una delle voci più autorevoli e originali della grafica contemporane

    Developments in managing severe chronic pain: role of oxycodone–naloxone extended release

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    Guido Fanelli,1 Andrea Fanelli2 1Anesthesia and Intensive Care Unit, University of Parma, Parma, 2Anesthesia and Intensive Care Unit, Policlinico S Orsola-Malpighi, Bologna, Italy Abstract: Chronic pain is a highly disabling condition, which can significantly reduce patients’ quality of life. Prevalence of moderate and severe chronic pain is high in the general population, and it increases significantly in patients with advanced cancer and older than 65 years. Guidelines for the management of chronic pain recommend opioids for the treatment of moderate-to-severe pain in patients whose pain is not responsive to initial therapies with paracetamol and/or nonsteroidal anti-inflammatory drugs. Despite their analgesic efficacy being well recognized, adverse events can affect daily functioning and patient quality of life. Opioid-induced constipation (OIC) occurs in 40% of opioid-treated patients. Laxatives are the most common drugs used to prevent and treat OIC. Laxatives do not address the underlying mechanisms of OIC; for this reason, they are not really effective in OIC treatment. Naloxone is an opioid receptor antagonist with low systemic bioavailability. When administered orally, naloxone antagonizes the opioid receptors in the gut wall, while its extensive first-pass hepatic metabolism ensures the lack of antagonist influence on the central-mediated analgesic effect of the opioids. A prolonged-release formulation consisting of oxycodone and naloxone in a 2:1 ratio was developed trying to reduce the incidence of OIC maintaining the analgesic effect compared with use of the sole oxycodone. This review includes evidence related to use of oxycodone and naloxone in the long-term management of chronic non-cancer pain and OIC. Keywords: chronic pain, opioid-induced constipation, opioids, oxycodone–naloxon

    On the molecular mechanisms driving pain perception and emergent collective behaviors

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    A stochastic model to investigate the microscopic processes which trigger the sensation of pain is considered. The model, presented in Di Patti and Fanelli [Di Patti F, Fanelli D. Can a microscopic stochastic model explain the emergence of pain cycles in patients? J Stat Mech 2009. doi:10.1088/1742-5468/2009/01/P01004], accounts for the action of analgesic drug and introduces an effect of competition with the inactive species populating the bloodstream. Regular oscillations in the amount of bound receptors are detected, following a resonant amplification of the stochastic component intrinsic to the system. The condition for such oscillations to occur are here studied, resorting to combined numerical and analytical techniques. Extended and connected patches of the admissible parameters space are detected which do correspond to the oscillatory behaviors. These findings are discussed with reference to the existing literature on patients' response to the analgesic treatment. © 2009 Elsevier B.V. All rights reserved

    Antropologia del PCI, a cura di Antonio Fanelli, Giovanni Pizza, Pino Schirripa

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    La sezione monografica dedicata all'Antropologia del Pci intende offrire ai lettori un quadro approfondito degli studi storici e antropologici legati al Partito comunista in una dimensione etnografica e antropologica che privilegia casi di studio empirici, quadri storici e una ampia ricostruzione del ruolo degli antropologi culturali italiani nelle fila del Pc

    Sara Roncaglia, Canti urbani: Trasformazioni del lavoro e degli spazi di vita a Mumbai, Milano, Raffaello Cortina, 2019, pp. 183

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    Book review of Sara Roncaglia, Canti urbani: Trasformazioni del lavoro e degli spazi di vita a Mumbai, Milano, Raffaello Cortina, 2019, pp. 183.Recensione di Sara Roncaglia, Canti urbani: Trasformazioni del lavoro e degli spazi di vita a Mumbai, Milano, Raffaello Cortina, 2019, pp. 183

    A Fuzzy Set Approach for Shape-Based Image Annotation

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    In this paper, we present a shape labeling approach for automatic image annotation. A fuzzy clustering process is applied to shapes represented by Fourier descriptors in order to derive a set of shape prototypes. Then, prototypes are manually annotated by textual labels corresponding to semantic categories. Based on the labeled prototypes, a new shape is automatically labeled by associating a fuzzy set that provides membership degrees of the shape to all semantic classes. Preliminary results show the suitability of the proposed approach to image annotation by encouraging its application in wider application contexts
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