1,720,991 research outputs found
Latissimus dorsi-rib pedicle flap for mandibular reconstruction as a salvage procedure for failed free fibula flap
No full textMandibular reconstruction is usually performed by using free vascular flaps. However, there are instances in which it must be carried out with pedicle flaps. Insofar, the main option recommended is the pectoralis major (PM) + rib pedicle flap
Evidence-Based Evaluation Technique to Assess Augmentation Mammaplasty Results: A Simple Method to Objectively Analyze Mammary Symmetry and Position.
No full textNodular cutaneous amyloidosis of the scalp reconstructed with a free anterolateral thigh flap: a case report
No full textN/
Response to letter: Adjustments to the round-the-clock technique for correction of gynecomastia
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Definizione e impiego dell’innesto di tessuto adiposo nella Sclerodermia
No full textLa Sclerodermia, è una malattia infiammatoria cronica del tessuto connettivo caratterizzata da alterazioni morfofunzionali dei piccoli vasi san- guigni (vasculopatia diffusa) e da modificazioni legate alla deposizione nei tessuti di collagene e di altri componenti della matrice connettivale (fibrosi), in particolare a livello della cute e di vari organi interni. Le opzioni terapeutiche per il miglioramento del trofismo tissutale nei pazienti sclerodermici includono l’applicazione di emulsioni e creme idratanti, l’utilizzo di filler e biostimolazione ed in particolare il lipofilling. Una metodica innovativa è l'impiego di cellule staminali mesenchimali derivate da tessuto adipose e coltivate in vitro., i principali vantaggi di quest'ultima metodica, sono stati la possibilità di trattare pazienti con scarso pannicolo adiposo (BMI<20), la scarsa invasività e una buona compliance da parte delle pazienti
Definizione e impiego dell’innesto di tessuto adiposo nella Sclerodermia
No full textLa Sclerodermia, è una malattia infiammatoria cronica del tessuto connettivo caratterizzata da alterazioni morfofunzionali dei piccoli vasi san- guigni (vasculopatia diffusa) e da modificazioni legate alla deposizione nei tessuti di collagene e di altri componenti della matrice connettivale (fibrosi), in particolare a livello della cute e di vari organi interni. Le opzioni terapeutiche per il miglioramento del trofismo tissutale nei pazienti sclerodermici includono l’applicazione di emulsioni e creme idratanti, l’utilizzo di filler e biostimolazione ed in particolare il lipofilling. Una metodica innovativa è l'impiego di cellule staminali mesenchimali derivate da tessuto adipose e coltivate in vitro., i principali vantaggi di quest'ultima metodica, sono stati la possibilità di trattare pazienti con scarso pannicolo adiposo (BMI<20), la scarsa invasività e una buona compliance da parte delle pazienti
Microsurgical Training with the Three-Step Approach
No full textBackground Microsurgery is very challenging, requiring a high degree of dexterity and manual skills that should be fully trained outside of the operating room. Common microsurgery courses usually follow a stepwise training approach beginning practice on nonliving models and proceeding with live rats. However, training on live rats raises certain issues, including ethical concerns as well as the associated costs. As such, there is an increasing drive toward alternative models. The current article describes a three-step training approach (latex glove-endovascular prosthesis-human placenta), which aims to prepare trainees for the clinical direct application. Also, to validate it, this approach was compared with microsurgical training on rats. Methods Overall, 20 residents were randomly assigned to two different microsurgical training courses, each based on one of the aforementioned approaches. Residents were evaluated in terms of correct handling of the instruments, correct use of the microscope, adventectomy, triangulation technique, posterior wall technique, success of the end-to-end anastomosis, and ability in assisting the tutor during the arterial anastomosis. Results The three-step and the live rats groups evidenced similar scores in term of acquired basic skill levels. Conclusions The three-step model allows to progressively gain skills on microsurgical techniques and to perform a good vascular anastomosis without the need of further steps on rats. The availability of both endovascular prosthesis and human placenta makes this training model definitely accessible from a practical and logistical point of view
Botulinum toxin for glabellar lines. A review of the efficacy and safety of currently available products
No full textFacial rhytides represent a widespread aesthetic concern. In particular, glabellar lines are perceived as a sign of aging and may give an erroneous impression of negative emotions. The onset of glabellar lines is closely related to the movements of the underlying muscles. Botulinum toxins inhibit the release of acetylcholine into the synaptic cleft and therefore result in temporary muscle paralysis. The observation that botulinum toxin (BTX) smoothed facial lines when used therapeutically led researchers to study the toxin effect on glabellar lines. Nowadays, the use of BTX to smooth glabellar frown lines represents the leading procedure in aesthetic facial treatments and an increasing number of BTX formulations are becoming available.This article provides a comparative evaluation of currently available BTX options for the treatment of glabellar lines. Toxins have been divided into three groups, based on whether they have obtained approval for cosmetic use (approved treatments) or not (off-label treatments), or whether they are still under investigation (experimental treatments). We examine the basic similarities and differences between available botulinum toxins, and summarize the pharmacokinetics and dosing.All approved treatments consist of BTX type A (BTX-A) and differ in their molecular weight, as some formulations are made of a BTX-A complex of 900kDa while the latest option on the market is a 150kDa BTX-A that is free from complexing proteins. As for the dosage, the important aspect that emerges from this comparison is that even within a given serotype, such as BTX-A, formulations are not interchangeable as each possesses distinctive characteristics that are attributed to the unique toxin purification and manufacturing processes. There is a substantial body of published evidence on the use of these approved treatments for facial enhancement, proving efficacy and safety. We investigate the methods of evaluation used for each toxin and review the safety and efficacy data reported in the literature. Minor adverse effects, such as headache, blepharoptosis, and injection-site reactions, are relatively frequent but transient, whilst major adverse effects are rare.Some botulinum toxins, i.e. BTX type B, that are approved for therapeutic applications are used off-label for cosmetic indications, thus without the approval of the health regulatory committees and without sufficient published evidence on safety and efficacy. As for experimental treatments, a number of BTX products are currently in development or have been recently launched for aesthetic applications. These products have been specifically designed to overcome some of the limitations present in the older generation of products. However, some of these toxins may be easily purchased via the Internet, without having any license or approval for cosmetic or therapeutic indications; these products must be considered unsafe and are potentially a severe health risk for patients. © 2011 Adis Data Information BV. All rights reserved
Extracorporeal Shock Wave Therapy for the treatment of venous ulcers in the lower limbs
No full textChronic venous ulcers are one of the most common medical problems today. The treatment has always been challenging and over the years many conservative and surgical alternatives have been proposed. During the past three decades, extracorporeal shock wave therapy (ESWT) has been introduced in several medical specialties. According to the clinical findings, the ESWT appears to significantly improve the healing process of chronic wounds, increasing the release of endogenous angiogenic factor from endothelial cells and fibroblasts, consequently fastening the healing process of chronic wounds. The present report describes the application of ESWT for the treatment of chronic venous ulcers in the lower limbs and compared the results with those obtained by conventional treatment on the contralateral leg
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