1,721,152 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
© 2010 Asian Network for Scientific Information An in Silico Development of Selective Inhibitor for Histamine Receptors
No full textAbstract: This study aimed to design a reliable homology model of human histamine H1 and H4 receptors (hH1R, hH4R), that would guide future biochemical and genetic efforts in its evaluation as a potential therapeutic target. Furthermore, these accurate models could aid in the structure-based inhibitor design for antagonists against the histamine H1 and H4 receptors. The homologous protein sequences of histamine receptors were retrieved from the NCBI REFSEQ which by using the sequence alignment program ClustalW alignment of the human histamine receptors sequence with Bovine Rhodopsin was conducted to locate the homology aligned regions. The present study found that Asp107 and Asn198 are in favorable positions for anchoring histamine. Identification of novel interaction sites for antagonist binding mutational data suggest a crucial role for Asp107, Trp158, Phe 432 and Phe 435 in antagonist binding. This study identified several novel amino acids at the binding site. Binding mode analysis of known H1 antagonists four known H1 antagonists (mepyramine, acrivastine, desloratadine, loratadine) were docked successfully to the binding site of the hH1R model by FlexiDock. The ligand used for optimizing the receptor model, the pharmacophore constraints and the different scoring functions applied in high throughput docking had all significant effect on the results. This research identified 16 compounds with 7 significant H4 activities representing an overall hit rate of 5.2%. To the best of our knowledge, this is one of the largest structure-based virtual screenings, where the virtual hits were confirmed by an in vitro assay. Moreover, this is the first structure-based drug design study reported on the hH4R. After the virtual screening, we identified several novel ligands with significant H4 affinity. These scaffolds can serve as starting points in the development of potent and selective H4 ligands in future
Commentary on a Cochrane Review of Hormone Therapy for Preventing Cardiovascular Disease in Postmenopausal Women
No full textkoamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Correlation of beta-thalassemia mutations with alpha-thalassemia: an experience of the southwestern region of Iran
No full text- …
