112 research outputs found
An actor network approach to the study of modernization processes: the case of the health care scheme in Morocco
No full textModernization through ICTs: an actor-network analysis of administrative reforms in Morocco
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Effects of diffusion coefficients and struts apposition using numerical simulations for drug eluting coronary stents
No full textIn the context of drug eluting stent, we present two-dimensional numerical models of mass transport of the drug in the wall and in the lumen to study the effect of the drug diffusion coefficients in the three principal media (blood, vascular wall, and polymer coating treated as a three-compartment problem) and the impact of different strut apposition configurations (fully embedded, half embedded, and not embedded). The different conditions were analyzed in terms of their consequence on the drug concentration distribution in the arterial wall. We apply the concept of the therapeutic window to the targeted vascular wall region and derive simple metrics to assess the efficiency of the various stent configurations. Although most of the drug is dispersed in the lumen, variations in the blood flow rate within the physiological range of coronary blood flow and the diffusivity of the drug molecule in the blood were shown to have a negligible effect on the amount of drug in the wall. Our results reveal that the amount of drug cumulated in the wall depends essentially on the relative values of the diffusion coefficients in the polymer coating and in the wall. Concerning the strut apposition, it is shown that the fully embedded strut configuration would provide a better concentration distribution
The temporal dimension of copresence in medical practice: the case of Telestroke
No full textThis paper examines how co-presence is enacted in technology-mediated medical practices, particularly under time pressure. Extant literature highlights time (e.g. immediacy and duration of interactions) as a critical condition for copresence, but there has been little attention to the variation of copresence over time. In this paper, we investigate this variation through an ethnographic study in three emergency departments that are linked via a telemedicine system called Telestroke, which is used to diagnose and treat stroke patients at a distance. We draw on the sensemaking literature to uncover how copresence is enacted across different phases of technology-mediated medical practice. Our findings reveal four mechanisms that shape the variation of copresence across time, namely extracting cues, retrospection, perspective-taking, and selective attention
Editorial Technology Assessment for Addressing Grand Societal Challenges
No full textEmerging technologies are both a cause of many grand societal challenges (GSCs) facing twenty-first-century societies and an integral part of some of their most promising solutions. As an element of the GSCs, technology becomes intertwined with several interrelated issues that constitute the GSCs. This calls for approaches to Technology Assessment (TA) that account for the paradoxical role of technology in the GSCs, and the imperative and complexity of pointing technological innovation toward addressing the GSCs. In this introduction to the special issue, we identify three major streams in TA research and practice, namely TA as a policy instrument, a deliberation process, and an issue field. These streams highlight tensions between relying on experts and on the inclusion of various stakeholders in TA processes, and between a TA framing around the intersection of technology and critical issues around critical issues, such as those constituting the GSCs. We discuss the advantages and challenges of each stream. We also outline and discuss key principles for conducting TA in the context of GSCs. We end by introducing the four papers that constitute this special issue.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Engineering, Systems and Service
INSTITUTIONAL TRANSFORMATION THROUGH DIGITAL PLATFORMS: ENABLERS AND INHIBITORS OF GROWTH IN EMERGING ECOSYSTEMS
No full textPh.DDOCTOR OF PHILOSOPH
Eskiyi Muhafaza Yeniyi Tervig: Medresè Islahati Risàlelerinin Dünyasi]
No full textThis article concerns Sheikh Ali Efendizade Hodja Muhyiddin's Medreselerin Islahi (Madrasah Reform), which is significant as the first and only tractate written before the Proclamation of the Second Constitutional Period. The tractate, which was published in 1897 in Egypt, is compared with the other published tractates of the madrasah people/the ulema of the Second Constitution. These include the works of Mehmed Faik Efendi of Diyarbekir, Vildan Faik Efendi, Aydin's deputy Mehmed Ubeydullah Efendi, Halim Sabit Efendi of Kazan, and Mehmed §evketi Efendi. By emphasizing the similar and different proposals and criticisms included in the tractates, self-criticism that was done by these writers who had madrasah roots or madrasah connections in one way or another is shown to be a sign of their knowledge on the topic in the process leading to Islah-i Medàris Nizamnàmesi (October 1, 1914). Although none of the aforementioned tractates can be qualified as an ideal reform text, a good joint text can be produced by considering all these tractates together, and this is partially apparent in the 1914 Regulations. © 2021, Istanbul 29 Mayis University - ISAM, TDV Centre for Islamic Studies. All rights reserved
3D characterization of the hemodynamic parameters in a stented coronary artery
No full textStenting is becoming the major interventional cardiology procedure worldwide. However restenosis remains a major limitation to the effectiveness of stents. Alterations to the local hemodynamics in the stented segment of the artery is a potential factor in the development of in-stent restenosis. The characterization of wall shear stress and of blood flow patterns in a stented artery is therefore necessary for a good understanding of the phenomenon. We have used a time-dependent 3D numerical model of a stented coronary artery to study the characteristics of the blood flow and the shear stress distribution. Our results show that the presence of the stent results in significant secondary flow. Regions of low shear stress were localized around the struts while the struts exhibited high values of shear stress. These results support the hypothesis that local hemodynamics may affect the development of in-stent restenosis and can guide the choice of stent geometries for future stent designs
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