177,128 research outputs found
Il danno al malato terminale
No full textSommario: 1. Premessa. - 2. Il c.d. danno biologico terminale. - 3. Il c.d. danno morale terminale. - 4. La liquidazione del danno biologico, in caso di premorienza del dannaeggiato. - 5. Il risarcimento del danno patrimoniale ai figli per la perdita del genitore. - 6. Segue. Il risarcimento del danno patrimoniale alla vedova
Ethnomusicology and Musical Education. Global or Local Perspective?
No full textThe paper presents and discusses some experiences in two Italian schools, where music coming from folk music around the world were proposed to pupils for playing or reinventing
Musica tradizionale della Lombardia a scuola: percorsi didattici
No full textTraditional music from the sound archive of Regione Lombardia (AESS) can be used in Italian school with many didactical purposes with historical, ethnographical o musicological approaches. In the article some songs and instrumental music ( work songs, narrative songs, dances)are analysed in order to propose didactic activitivies
Responsabilità per danno da prodotti difettosi, commento agli art. 114- 127, D.L.vo 6 settembre 2005, n. 206.
No full textIl lavoro consiste in un commento, articolo per articolo, alla disciplina della responsabilità del produttore, di cui al d.P.R. n. 224 del 1988, confluita nel Codice del Consumo, di cui al D.L.vo 6 settembre 2005, n. 206
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Tuning molecular orientation in protein films
No full textThe rational design of azurin metalloprotein assemblies suitable for biomolecular electronics application has been achieved by exploiting different surface chemical approaches for growing active protein layers on both metal and insulating surfaces. The formed layers, which have been tested extensively by scanning force microscopy (SFM), spectroscopic ellipsometry, X-ray photoelectron spectroscopy (XPS), and electrochemical measurements (cyclic and linear voltammetry (CV and LV)), consist of redox active molecules endowed with tuneable orientation according to the particular functional group exploited for surface immobilization. The peculiar molecular arrangement has turned out to be responsible for different transport properties in solid state hybrid electronic planar devices
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Intracellular Ion Channel CLIC1: Involvement In Microglia-Mediated ß-Amyloid Peptide(1-42) Neurotoxicity
No full textMicroglia can exacerbate central nervous system disorders, including stroke and chronic progressive neurodegenerative diseases such as Alzheimer disease. Mounting evidence points to ion channels expressed by microglia as contributing to these neuropathologies. The Chloride Intracellular Channel (CLIC) family represents a class of chloride intracellular channel proteins, most of which are localized to intracellular membranes. CLICs are unusual in that they possess both soluble and integral membrane forms. Amyloid beta-peptide (A beta) accumulation in plaques is a hallmark of familial Alzheimer disease. The truncated A beta(25-35) species was shown previously to increase the expression of CLIC1 chloride conductance in cortical microglia and to provoke microglial neurotoxicity. However, the highly pathogenic and fibrillogenic full-length A beta(1-42) species was not examined, nor was the potential role of CLIC1 in mediating microglial activation and neurotoxicity by other stimuli (e.g. ligands for the Toll-like receptors). In the present study, we utilized a two chamber Transwell (TM) cell culture system to allow separate treatment of microglia and neurons while examining the effect of pharmacological blockade of CLIC1 in protecting cortical neurons from toxicity caused by A beta(1-42)- and lipopolysaccaride-stimulated microglia. Presentation of A beta(1-42) to the upper, microglia-containing chamber resulted in a progressive loss of neurons over 3 days. Neuronal cell injury was prevented by the CLIC1 ion channel blockers IAA-94 [(R(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5yl)-oxy] acetic acid)] and niflumic acid (2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid) when presented to the upper chamber only. Incubation of microglia with lipopolysaccharide plus interferon-gamma led to neuronal cell injury which, however, was insensitive to inhibition by the CLIC1 channel blockers, suggesting a degree of selectivity in agents leading to CLIC1 activation
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
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