1,765,770 research outputs found
Fabienne Chouraqui
No full textChouraqui Fabienne. Fabienne Chouraqui. In: Diplômées, n°238, 2011. Femmes diplômées de l’enseignement supérieur et temps partiel. pp. 159-160
Fabienne Wateau, Antagonismes et irrigation. Organisation d'une communauté paysanne du nord-ouest du Portugal
No full textWateau Fabienne. Fabienne Wateau, Antagonismes et irrigation. Organisation d'une communauté paysanne du nord-ouest du Portugal. In: Recherches en anthropologie au Portugal, n°1, 1998. pp. 129-132
The role of Sprouty4 in development and cancer and functional consequences of Sprouty interacting with Caveolin-1
Get PDFintracellular signaling pathways that ultimately determine cell fate. The coordinated action of both positive and negative modulators is essential for spatial and temporal control of these pathways to avoid developmental defects and malignant transformation. Sprouty (Spry) proteins are a family of ligand-induced regulators of RTK-mediated intracellular cascades. In mammals, there are four isoforms. Their activity targets signal transduction induced by various growth factors, suggesting that their activities have broad biological consequences. Spry proteins have the capacity to attenuate or potentiate different pathways depending on the Spry isoform, the growth factor and the cellular context. In this study I investigate the functional consequences of Spry interacting with Caveolin-1. I demonstrate that in the context of FGF2 and EGF signaling, Caveolin-1 differentially modulates the function of the four isoforms. This suggests that Caveolin-1 might contribute to the divergence among the four isoforms and, depending on its own expression pattern, could contribute to the cell context-dependency of Spry proteins. In a second part of my studies I assess the role of mSpry4 in murine pancreas development. Analyzing this organ for the presence of Spry proteins, I detect very specific expression of mSpry4 in one population of endocrine cells, namely in the α cells. In the pancreas, different endocrine cell types are organized within islets of Langerhans. The insulin-secreting β cells occupy the core of the islets and are surrounded by α, δ and PP cells, secreting glucagon, somatostatin and pancreatic polypeptide, respectively. Using a doxycycline-inducible transgenic system I conditionally express mSpry4 in the insulinproducing β cells and demonstrate that ectopic mSpry4 interferes with proper segregation of the endocrine cells. Employing the endocrine precursor cell line PANC-1 as an in vitro model for islet formation I find that mSpry4 inhibits migration and adhesion of these cells, probably by interfering with the localization PTP1B, a mediator of integrin signaling. Furthermore, the role of mSpry4 in tumorigenesis was assessed using the well established Rip1Tag2 mouse model. In these mice, transgenic expression of large T antigen results in β cell carcinogenesis. We find that expression of mSpry4 in β cells has a moderate effect on tumor formation. Experiments with isolated tumor cells imply that transformation of β cells by means of large T antigen results in constitutive activation of p42/44 ERK signaling by a mechanism that renders mSpry4 ineffective as an inhibitor of this pathway
Quand l’invisible s’affiche Entretien avec Fabienne Kanor: Inscrire et réitérer des identités ouvertes, mouvantes et complexes
Get PDFCet article enclot un entretien entre la cinéaste martiniquaise Fabienne Kanor et Gladys M. Francis, chercheure en études francophones et culturelles. Il examine le septième art aux Antilles dans notre ère contemporaine, la politique artistique féministe de Kanor, ainsi que les enjeux qui prennent forme dans l’acte de filmer et genre et minorité sexuelle aux Antilles. Cette entrevue met également en lumière la manière dont ses productions visuelles dérogent (aux sociétés traditionnelles/phallocentriques/impérialistes) afin de provoquer une esthétique et des représentations du corps noir novatrices.
Martinican film-maker Fabienne Kanor speaks with francophone and cultural studies scholar Dr Gladys M. Francis about her feminist politics of art, the meaning of filming gender and sexual minorities in the French Caribbean, and the position of art in the French Antilles today. The interview sheds light on the ways in which her visual productions disrupt (traditional/phallocentric/imperialist) society and offer challenging aesthetics and representations of the Black body.Originally published in
Francis, Gladys M. 2019. “Quand l’invisible s’affiche Entretien Avec Fabienne Kanor.” Francosphères 8 (1): 85–100. https://doi.org/10.3828/franc.2019.6
Abschied von Fabienne
No full textFabienne Kneifel, verh. Wassermann ist am 19. Juni 2014, kurz vor ihrem 33. Geburtstag, gestorben. Ihren Namen verbindet man in der Bibliothekswelt sofort mit den Begriffen der Bibliothek 2.0 und dem Katalog der nächsten Generation. Ihre Masterarbeit „Mit Web 2.0 zum Online-Katalog der nächsten Generation“ an der HU Berlin 2008 wurde 2009 b.i.t. Innovationspreis ausgezeichnet. Für das „Handbuch Bibliothek 2.0“ steuerte sie das Kapitel „Katalog 2.0“ bei. Fabienne kam ganz traditionell über die..
A cross-country study on female leadership: women in executive positions
No full textAuthor Carolin Fabienne BeaaMasterarbeit Johannes Kepler Universität Linz 2024Arbeit auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Abschied von der Idylle. Fabienne Ruppen im Interview mit Christof Nüssli, Christoph Oeschger und Miklós Klaus Rózsa
Get PDFDie Publikation «Miklós Klaus Rózsa» basiert auf dem Archiv des
gleichnamigen Fotografen und politischen Aktivisten (*1954).
Christof Nüssli und Christoph Oeschger kombinieren die in den 1970er-
und 1980er-Jahren über Rózsa verfassten Staatsschutzakten mit
dessen Fotografien und zeigen so, wie die beiden Seiten ein
und dasselbe Ereignis jeweils anders schildern. Mit Fabienne Ruppen
sprachen sie über das verklärte Bild von der Schweiz im Ausland,
über die NSA und Beweismittel fälschende Polizisten
Fabienne Auzolle
No full textErnould-Gandouet Marielle. Fabienne Auzolle. In: Sèvres. Revue de la Société des Amis du musée national de Céramique, n°24, 2015. pp. 142-146
BERTON Fabienne
No full textSavoie Philippe. BERTON Fabienne. In: , . Un nouveau champ pour l'histoire: économie et finances de l'éducation. Annuaire des chercheurs. Paris : Institut national de recherche pédagogique, 1993. pp. 19-20. (Bibliothèque de l'Histoire de l'Education, 27
BERTON Fabienne
No full textSavoie Philippe. BERTON Fabienne. In: Un nouveau champ pour l'histoire: économie et finances de l'éducation. Annuaire des chercheurs. Paris : Institut national de recherche pédagogique, 1993. pp. 19-20. (Bibliothèque de l'Histoire de l'Education, 27
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