143 research outputs found

    Patente del Comisario General de los Franciscanos en Nueva España estableciendo la Custodia de la Florida, 1607 mayo 11

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    Patente que el Padre Comisario General de la Nueva España, fray Juan de Cieza, envía a los Religiosos de la Custodia de la Florida. En el patente, Cieza confirma y da autoridad ordinaria al Padre fray Francisco Pareja como legítimo prelado y custodio electo de la Custodia de Florida y a los definidores, Padre fray Pedro Ruíz, Padre Fray Juan Capilla, Padre fray Bartolomé Romero, y Padre fray Alonso Serrano. Cieza también confirma el establecimiento de las siguientes guardianías y conventos: Nuestra Santa de la Concepción, San Juan del Puerto, Santa Catalina de Guale, San Pedro Atululteca, Nombre de Dios Amacarisi, San Buenaventura de Guadalquini, y San Francisco de Moloa. El Comisario General también delinea procesos administrativos de la nueva custodia. —— Patent that the General Commissioner of New Spain, Fray Juan de Cieza, sent the Franciscans of the Custody of Florida. In the patent, Cieza confirms and gives ordinary authority to Father Fray Francisco Pareja as legitimate prelate and elected custodian of the Custody of Florida and to the definers Father Fray Pedro Ruíz, Father Fray Juan Capilla, Father Fray Bartolomé Romero, and Father Fray Alonso Serrano. Cieza also confirms the establishment of the following guardianships and convents: Nuestra Santa de la Concepción, San Juan del Puerto, Santa Catalina de Guale, San Pedro Atululteca, Nombre de Dios Amacarisi, San Buenaventura de Guadalquini, and San Francisco de Moloa. The Commissioner General also outlines administrative processes of the new custody. 2 f. (4 p.

    The Role of Glia in Alzheimer's Disease

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    This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac

    La Rebelión de Los Esclavos: Tragedia y posibilidad en el teatro de Raúl Hernández Garrido

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    Thesis advisor: Irene MizrahiThis study is an analysis of the theatre of the Spanish contemporary playwright Raúl Hernández Garrido. It explores in depth his tragedy Los engranajes and it applies (in a more referential manner) the results of this investigation to the rest of his plays: Los malditos, Los restos: Agamenón vuelve a casa and Los restos Fedra, included in the cycle Los esclavos. The author utilizes myth and greek tragedy intentionally in order to make readers reflect upon the concepts of destiny and the fragility of human action as well as the fragmentation, hopelessness and dissatisfaction of contemporary societies. My study demonstrates that the formal innovation of these plays and the use of tragedy as their argumental framework present not only a criticism about these concepts but also an approach towards change and a social ethic of hope founded in creative freedom and the cooperation between the text and all people involved in the creative process. As a theoretical frame of reference for my study I use texts from Sigmund Freud, Jacques Lacan, Friedrich Nietzsche, René Girard and Emmanuel Levinas. Their reflections about the genre of tragedy and/or the concept of the tragic shed light upon my analysis of themes such as human suffering, trauma, the abuse of power, violence and the ethics of responsibility in the works of our author.Thesis (PhD) — Boston College, 2011.Submitted to: Boston College. Graduate School of Arts and Sciences.Discipline: Romance Languages and Literatures

    The fantastic in Spain during the late- nineteenth and early-twentieth centuries

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    This thesis has as its primary objective the drawing together and subsequent theorisation of diverse texts which can be understood to be examples of Spanish fantastic literature. It demonstrates that from nineteenth-century Realism and Naturalism (exemplified in narratives by Pérez Galdós, Alarcón and Pardo Bazán), through turn-of-the-century modernismo (Valle-Inclán and Zamacois) to twentieth- century proto-existentialism (Unamuno), a significant number of texts were produced which, in spite of the obvious differences between them, refute the widely held idea that 'the fantastic' and Spanish literature share little common ground. The thesis is therefore one more step along the journey of establishing that Spanish fantastic literature is as important and integral to the whole swathe of Spanish cultural production as it is in many other European countries. The critical analyses of the narratives push at the boundaries of previous interpretative strategies both in terms of the fantastic and of the texts themselves. The exception to this interrogation and reinvigoration of earlier interpretations is to be found in the approach to the narratives by Zamacois, which have hitherto received very little critical attention. These detailed readings draw out the complexities and intriguing perspectives which the fantastic in Spain presents to the attentive reader. By means of these textual analyses, the thesis also explores some of the various possibilities presented by the fantastic itself, putting flesh on the theoretical bones of several different critical discourses. Ultimately, this thesis charts a dynamic and coherent corpus of material which represents the process of the psychologisation of the supernatural from Romanticism onwards. Each successive text more starkly expresses the unreal horrors of the fractured human mind, as well as the mutations of the body. As such, the evolutionary history of the fantastic in Spain is shown to be more gripping and relevant than has hitherto been understood to be the case

    The developmental cell biology of Trypanosoma brucei

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    Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which it must adapt either to the mammalian bloodstream or to different compartments within the tsetse fly. These differentiation events require stage-specific changes to basic cell biological processes and reflect responses to environmental stimuli and programmed differentiation events that must occur within a single cell. The organization of cell structure is fundamental to the trypanosome throughout its life cycle. Modulations of the overall cell morphology and positioning of the specialized mitochondrial genome, flagellum and associated basal body provide the classical descriptions of the different life cycle stages of the parasite. The dependency relationships that govern these morphological changes are now beginning to be understood and their molecular basis identified. The overall picture emerging is of a highly organized cell in which the rules established for cell division and morphogenesis in organisms such as yeast and mammalian cells do not necessarily apply. Therefore, understanding the developmental cell biology of the African trypanosome is providing insight into both fundamentally conserved and fundamentally different aspects of the organization of the eukaryotic cell

    Assessment of avocado textural changes during ripening by using contactless air-coupled ultrasound

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    [EN] In the present study, the use of the air-coupled ultrasonic technique has been analysed as a new tool for the contactless assessment of the avocado post-harvest textural modifications during ripening. Thus, ultrasonic parameters, such as maximum wave amplitude and ultrasound velocity, and textural ones, such as hardness, elastic modulus and relaxation capacity, were measured on avocado slices. During ripening, avocado reduced its elastic modulus (from 2.29 +/- 0.75 to 0.16 +/- 0.08 MPa), became softer and became more viscoelastic, which was well described from zero and first-order kinetic models. These changes increased ultrasound attenuation, decreasing the maximum amplitude of the ultrasonic signal (from 336.6 to 55.4 V/m), while the ultrasonic velocity remained constant, between 320.1 +/- 6.9 and 316.4 +/- 82.6 m/s. Thereby, the maximum ultrasonic amplitude, which adequately correlated with textural parameters (r(avg) = 0.85), could be used to assess the post-harvest ripening on avocado slices.The authors acknowledge the financial support from the Ministerio de Economia y Competitividad (MINECO) and Agencia Estatal de InvestigaciOn in Spain (Project RTC-2017-6314-2) and the Generalitat Valenciana. M.D. Farifias is grateful to the European Social Fund (ESF 2014-2020) and Generalitat Valenciana for her post-doctoral fellowship (APOSTD/2018/203). The author E.A. Sanchez-Torres acknowledges the support of the undergraduate student Sara Serrano Garcia on the experimental work.Fernandez-Caballero-Fariñas, MD.; Sanchez-Torres, EA.; Sanchez-Jimenez, V.; Díaz, R.; Benedito Fort, JJ.; Garcia-Perez, J. (2021). Assessment of avocado textural changes during ripening by using contactless air-coupled ultrasound. Journal of Food Engineering. 289:1-9. https://doi.org/10.1016/j.jfoodeng.2020.110266S1928

    Currency Hedging Strategies Using Dynamic Multivariate GARCH

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    The authors are most grateful for the helpful comments and suggestions of Michael McAleer, Teodosio Perez Amaral, two referees, and participants at the international Conference on Risk Modelling and Management, Madrid, Spain, June 2011. The first author is most grateful for the financial support of the National Science Council, Taiwan, and the second author acknowledges the financial support of the Ministerio de Ciencia y Tecnología and Comunidad de Madrid, Spain.This paper examines the effectiveness of using futures contracts as hedging instruments of: (1) alternative models of volatility for estimating conditional variances and covariances; (2) alternative currencies; and (3) alternative maturities of futures contracts. For this purpose, daily data of futures and spot exchange rates of three major international currencies, Euro, British pound and Japanese yen, against the American dollar, are used to analyze hedge ratios and hedging effectiveness resulting from using two different maturity currency contracts, near-month and next-to-near-month contract. Following Chang et al. [17], we estimate four multivariate volatility models (namely CCC, VARMA-AGARCH, DCC and BEKK), and calculate optimal portfolio weights and optimal hedge ratios to identify appropriate currency hedging strategies. The hedging effectiveness index suggests that the best results in terms of reducing the variance of the portfolio are for the USD/GBP exchange rate. The empirical results show that futures hedging strategies are slightly more effective when the near-month future contract is used for the USD/GBP and USD/JPY currencies. Moreover, the CCC and AGARCH models provide similar hedging effectiveness, which suggests that dynamic asymmetry may not be crucial empirically, although some differences appear when the DCC and BEKK models are used.Fac. de Ciencias Económicas y EmpresarialesInstituto Complutense de Análisis Económico (ICAE)TRUEpu

    User involvement in a Cochrane systematic review: using structured methods to enhance the clinical relevance, usefulness and usability of a systematic review update

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    Background: This paper describes the structured methods used to involve patients, carers and health professionals in an update of a Cochrane systematic review relating to physiotherapy after stroke and explores the perceived impact of involvement.Methods: We sought funding and ethical approval for our user involvement. We recruited a stakeholder group comprising stroke survivors, carers, physiotherapists and educators and held three pre-planned meetings during the course of updating a Cochrane systematic review. Within these meetings, we used formal group consensus methods, based on nominal group techniques, to reach consensus decisions on key issues relating to the structure and methods of the review.Results: The stakeholder group comprised 13 people, including stroke survivors, carers and physiotherapists with a range of different experience, and either 12 or 13 participated in each meeting. At meeting 1, there was consensus that methods of categorising interventions that were used in the original Cochrane review were no longer appropriate or clinically relevant (11/13 participants disagreed or strongly disagreed with previous categories) and that international trials (which had not fitted into the original method of categorisation) ought to be included within the review (12/12 participants agreed or strongly agreed these should be included). At meeting 2, the group members reached consensus over 27 clearly defined treatment components, which were to be used to categorise interventions within the review (12/12 agreed or strongly agreed), and at meeting 3, they agreed on the key messages emerging from the completed review. All participants strongly agreed that the views of the group impacted on the review update, that the review benefited from the involvement of the stakeholder group, and that they believed other Cochrane reviews would benefit from the involvement of similar stakeholder groups.Conclusions: We involved a stakeholder group in the update of a Cochrane systematic review, using clearly described structured methods to reach consensus decisions. The involvement of stakeholders impacted substantially on the review, with the inclusion of international studies, and changes to classification of treatments, comparisons and subgroup comparisons explored within the meta-analysis. We argue that the structured approach which we adopted has implications for other systematic reviews.</p

    Overview of the Instrumentation for the Dark Energy Spectroscopic Instrument

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    Full list of authors: Abareshi, B.; Aguilar, J.; Ahlen, S.; Alam, Shadab; Alexander, David M.; Alfarsy, R.; Allen, L.; Allende Prieto, C.; Alves, O.; Ameel, J.; Armengaud, E.; Asorey, J.; Aviles, Alejandro; Bailey, S.; Balaguera-Antolinez, A.; Ballester, O.; Baltay, C.; Bault, A.; Beltran, S. F.; Benavides, B.; BenZvi, S.; Berti, A.; Besuner, R.; Beutler, Florian; Bianchi, D.; Blake, C.; Blanc, P.; Blum, R.; Bolton, A.; Bose, S.; Bramall, D.; Brieden, S.; Brodzeller, A.; Brooks, D.; Brownewell, C.; Buckley-Geer, E.; Cahn, R. N.; Cai, Z.; Canning, R.; Capasso, R.; Carnero Rosell, A.; Carton, P.; Casas, R.; Castander, F. J.; Cervantes-Cota, J. L.; Chabanier, S.; Chaussidon, E.; Chuang, C.; Circosta, C.; Cole, S.; Cooper, A. P.; da Costa, L.; Cousinou, M-C; Cuceu, A.; Davis, T. M.; Dawson, K.; De la Cruz-Noriega, R.; de la Macorra, A.; de Mattia, A.; Della Costa, J.; Demmer, P.; Derwent, M.; Dey, A.; Dey, B.; Dhungana, G.; Ding, Z.; Dobson, C.; Doel, P.; Donald-McCann, J.; Donaldson, J.; Douglass, K.; Duan, Y.; Dunlop, P.; Edelstein, J.; Eftekharzadeh, S.; Eisenstein, D. J.; Enriquez-Vargas, M.; Escoffier, S.; Evatt, M.; Fagrelius, P.; Fan, X.; Fanning, K.; Fawcett, V. A.; Ferraro, S.; Ereza, J.; Flaugher, B.; Font-Ribera, A.; Forero-Romero, J. E.; Frenk, C. S.; Fromenteau, S.; Gansicke, B. T.; Garcia-Quintero, C.; Garrison, L.; Gaztanaga, E.; Gerardi, F.; Gil-Marin, H.; Gontcho, S. Gontcho A.; Gonzalez-Morales, Alma X.; Gonzalez-de-Rivera, G.; Gonzalez-Perez, V; Gordon, C.; Graur, O.; Green, D.; Grove, C.; Gruen, D.; Gutierrez, G.; Guy, J.; Hahn, C.; Harris, S.; Herrera, D.; Herrera-Alcantar, Hiram K.; Honscheid, K.; Howlett, C.; Huterer, D.; Irsic, V; Ishak, M.; Jelinsky, P.; Jiang, L.; Jimenez, J.; Jing, Y. P.; Joyce, R.; Jullo, E.; Juneau, S.; Karacayli, N. G.; Karamanis, M.; Karcher, A.; Karim, T.; Kehoe, R.; Kent, S.; Kirkby, D.; Kisner, T.; Kitaura, F.; Koposov, S. E.; Kovacs, A.; Kremin, A.; Krolewski, Alex; L'Huillier, B.; Lahav, O.; Lambert, A.; Lamman, C.; Lan, Ting-Wen; Landriau, M.; Lane, S.; Lang, D.; Lange, J. U.; Lasker, J.; Le Guillou, L.; Leauthaud, A.; Suu, A. Le Van; Levi, Michael E.; Li, T. S.; Magneville, C.; Manera, M.; Manser, Christopher J.; Marshall, B.; Martini, Paul; McCollam, W.; McDonald, P.; Meisner, Aaron M.; Mena-Fernandez, J.; Meneses-Rizo, J.; Mezcua, M.; Miller, T.; Miquel, R.; Montero-Camacho, P.; Moon, J.; Moustakas, J.; Mueller, E.; Munoz-Gutierrez, Andrea; Myers, Adam D.; Nadathur, S.; Najita, J.; Napolitano, L.; Neilsen, E.; Newman, Jeffrey A.; Nie, J. D.; Ning, Y.; Niz, G.; Norberg, P.; Noriega, Hernan E.; O'Brien, T.; Obuljen, A.; Palanque-Delabrouille, N.; Palmese, A.; Zhiwei, P.; Pappalardo, D.; Peng, X.; Percival, W. J.; Perruchot, S.; Pogge, R.; Poppett, C.; Porredon, A.; Prada, F.; Prochaska, J.; Pucha, R.; Perez-Fernandez, A.; Perez-Rafols, I; Rabinowitz, D.; Raichoor, A.; Ramirez-Solano, S.; Ramirez-Perez, Cesar; Ravoux, C.; Reil, K.; Rezaie, M.; Rocher, A.; Rockosi, C.; Roe, N. A.; Roodman, A.; Ross, A. J.; Rossi, G.; Ruggeri, R.; Ruhlmann-Kleider, V; Sabiu, C. G.; Safonova, S.; Said, K.; Saintonge, A.; Catonga, Javier Salas; Samushia, L.; Sanchez, E.; Saulder, C.; Schaan, E.; Schlafly, E.; Schlegel, D.; Schmoll, J.; Scholte, D.; Schubnell, M.; Secroun, A.; Seo, H.; Serrano, S.; Sharples, Ray M.; Sholl, Michael J.; Silber, Joseph Harry; Silva, D. R.; Sirk, M.; Siudek, M.; Smith, A.; Sprayberry, D.; Staten, R.; Stupak, B.; Tan, T.; Tarle, Gregory; Tie, Suk Sien; Tojeiro, R.; Urena-Lopez, L. A.; Valdes, F.; Valenzuela, O.; Valluri, M.; Vargas-Magana, M.; Verde, L.; Walther, M.; Wang, B.; Wang, M. S.; Weaver, B. A.; Weaverdyck, C.; Wechsler, R.; Wilson, Michael J.; Yang, J.; Yu, Y.; Yuan, S.; Yeche, Christophe; Zhang, H.; Zhang, K.; Zhao, Cheng; Zhou, Rongpu; Zhou, Zhimin; Zou, H.; Zou, J.; Zou, S.; Zu, Y.; DESI Collaboration.--This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.The Dark Energy Spectroscopic Instrument (DESI) embarked on an ambitious 5 yr survey in 2021 May to explore the nature of dark energy with spectroscopic measurements of 40 million galaxies and quasars. DESI will determine precise redshifts and employ the baryon acoustic oscillation method to measure distances from the nearby universe to beyond redshift z > 3.5, and employ redshift space distortions to measure the growth of structure and probe potential modifications to general relativity. We describe the significant instrumentation we developed to conduct the DESI survey. This includes: a wide-field, 3fdg2 diameter prime-focus corrector; a focal plane system with 5020 fiber positioners on the 0.812 m diameter, aspheric focal surface; 10 continuous, high-efficiency fiber cable bundles that connect the focal plane to the spectrographs; and 10 identical spectrographs. Each spectrograph employs a pair of dichroics to split the light into three channels that together record the light from 360–980 nm with a spectral resolution that ranges from 2000–5000. We describe the science requirements, their connection to the technical requirements, the management of the project, and interfaces between subsystems. DESI was installed at the 4 m Mayall Telescope at Kitt Peak National Observatory and has achieved all of its performance goals. Some performance highlights include an rms positioner accuracy of better than 0farcs1 and a median signal-to-noise ratio of 7 of the [O ii] doublet at 8 × 10−17 erg s−1 cm−2 in 1000 s for galaxies at z = 1.4–1.6. We conclude with additional highlights from the on-sky validation and commissioning, key successes, and lessons learned. © 2022. The Author(s). Published by the American Astronomical Society.This research is supported by the Director, Office of Science, Office of High Energy Physics of the U.S. Department of Energy under contract No. DE-AC02-05CH11231, and by the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility under the same contract. Additional support for DESI is provided by the U.S. National Science Foundation, Division of Astronomical Sciences under contract No. AST-0950945 to the NSF's National Optical-Infrared Astronomy Research Laboratory; the Science and Technologies Facilities Council of the United Kingdom; the Gordon and Betty Moore Foundation; the Heising–Simons Foundation; the French Alternative Energies and Atomic Energy Commission (CEA); the National Council of Science and Technology of Mexico (CONACYT); the Ministry of Science and Innovation of Spain, and by the DESI Member Institutions: Aix-Marseille University; Argonne National Laboratory; Barcelona-Madrid Regional Participation Group; Brookhaven National Laboratory; Boston University; Brazil Regional Participation Group; Carnegie Mellon University; CEA-IRFU, Saclay; China Participation Group; Cornell University; Durham University; École Polytechnique Fédérale de Lausanne; Eidgenössische Technische Hochschule, Zürich; Fermi National Accelerator Laboratory; Granada-Madrid-Tenerife Regional Participation Group; Harvard University; Kansas State University; Korea Astronomy and Space Science Institute; Korea Institute for Advanced Study; Lawrence Berkeley National Laboratory; Laboratoire de Physique Nucléaire et de Hautes Energies; Ludwig Maximilians University; Max Planck Institute; Mexico Regional Participation Group; New York University; NSF's National Optical-Infrared Astronomy Research Laboratory; Ohio University; Perimeter Institute; Shanghai Jiao Tong University; Siena College; SLAC National Accelerator Laboratory; Southern Methodist University; Swinburne University; The Ohio State University; Universidad de los Andes; University of Arizona; University of Barcelona; University of California, Berkeley; University of California, Irvine; University of California, Santa Cruz; University College London; University of Florida; University of Michigan at Ann Arbor; University of Pennsylvania; University of Pittsburgh; University of Portsmouth; University of Queensland; University of Rochester; University of Toronto; University of Utah; University of Waterloo; University of Wyoming; University of Zurich; UK Regional Participation Group; and Yale University. This work has made use of data from the European Space Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by the Gaia Data Processing and Analysis Consortium (DPAC; https://www.cosmos.esa.int/web/gaia/dpac/consortium). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement.With funding from the Spanish government through the Severo Ochoa Centre of Excellence accreditation SEV-2017-0709.Peer reviewe
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