1,720,969 research outputs found

    Clinical efficacy of gamma-hydroxybutyric acid in treatment of opiate withdrawal

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    This paper describes the role of gamma-hydroxybutyric acid (GHB) in the treatment of opiate withdrawal syndrome. In the two patients described, after having abruptly withdrawn from long-term methadone treatment, GHB was orally administered (each dose given every 46 h) for 8-9 days. The GHB showed both a high efficacy (some mild and transient symptoms attributable to opiate withdrawal were observed, but only in the first days of therapy) and a good tolerability (no clinical phenomena interpreted as GHB side effects were found). These results could be of interest in improving the pharmacological treatment of drug addiction

    “Il vizio di respirare”: rilevazioneepidemiologica sull’abitudine al fumo tra igiovani

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    INTRODUZIONE: Dall’indagine ISS-Doxa sul fumo del 2010 emerge che nella fascia d’età dai 15-24 anni il 21.9% dei ragazzi è abituale fumatore. Per ridurre la diffusione del fumo nei soggetti adulti, è indispensabile ridurre il numero delle persone che iniziano a fumare in giovane età. Secondo i dati della letteratura infatti le persone che non iniziano a fumare durante l’adolescenza, hanno una bassa probabilità di diventare un fumatore regolare in età adulta. Obiettivo dello studio è quello di valutare l’abitudine al fumo di alunni delle classi medie e superiori ed i fattori che aumentano il rischio di incorrere in questo vizio.METODI: Nel corso dell’anno scolastico 2009-2010, hanno aderito al progetto “Il vizio di respirare”, per la prevenzione del fumo di sigaretta nei giovani, 9 scuole medie inferiori e 7 istituti superiori della Provincia di Padova ed ha coinvolto un numero complessivo di 1580 soggetti. E’stato somministrato un questionario QAT (questionario sugli adolescenti ed il fumo) che mirava ad indagare le condizioni demografiche, ambientali e sociali che inducono il giovane ad iniziare a fumare. RISULTATI: Dalla rilevazione emerge che il 31.1% del campione ha provato almeno una volta a fumare ed il 16.6% è attualmente fumatore. Se analizzato il dato per classe frequentata, si osserva che tra i soggetti di prima media il 5.6% ha provato a fumare ed il 51.7% tra gli studenti di prima superiore. Inoltre in prima media solo l’1% è attuale fumatore, ma in prima superiore il 28.9% si dichiara fumatore abituale, tra questi il 53,9% è maschio e il 46.1% è femmina. Gli studenti fumatori delle superiori dichiarano inoltre di aver iniziato a fumare in media 12.7 mesi prima. La probabilità di essere fumatore alle superiori è del 3.6% se il ragazzo non ha tra i migliori amici nessun fumatore, del 21.8% se ha un amico fumatore, il 32.9% se due amici fumatori, il 61.5% se tre amici fumatori, l’85.0% se tutti fumano. L’abitudine al fumo non è associata al ruolo che il ragazzo ritiene di avere nel gruppo di amici o alla forza legame del ragazzo con il gruppo è invece associato alle dimensioni e alle caratteristiche del gruppo: maggiore probabilità di essere fumatori si osserva nei soggetti che frequentano grandi gruppi e più contrari alle regole. Nei ragazzi fumatori inoltre emerge come sia maggiore la percezione delle quantità di sigarette fumate dall’insegnate che stimano di più e dai propri genitori. CONCLUSIONI: I dati confermano che già all’età di 13-14 anni il 28.9% dei ragazzi inizia ad essere fumatore abituale e che il contesto ambientale influenza il rischio della dipendenza

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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